Glutathione, wotchedwanso GSH, ndi molekyu yomwe imapezeka mwachibadwa m'thupi lanu. Wopangidwa ndi chiwindi, glutathione imapangidwa ndi atatu amino acid: L-cysteine, glycine, ndi L-glutamate. Glutathione imaganiza kuti imapereka antioxidant zotsatira, komanso zimathandiza kuti chitetezo cha mthupi chitengeke. Otsutsa akuti glutathione zowonjezereka zingathandize kuthandizira ndi kupewa matenda ambiri.
Komanso mumapezeka zakudya zina (monga zipatso ndi ndiwo zamasamba), glutathione imagulitsidwa pa fomu yowonjezera zakudya. Ngakhale kuti glutathione ndi ofunika kwambiri m'thupi, pakamwa pamatenda a glutathione amagawidwa ku ma antioxidants atatu, ndipo amapindula chifukwa cha L-cysteine.
Ntchito
Glutathione amatetezedwa motsutsana ndi matenda osiyanasiyana, kuphatikizapo: uchidakwa , matenda a Alzheimer's , asthma , atherosclerosis , autism, cataracts , matenda odwala matenda a shuga , colitis , matenda a shuga , glaucoma , matenda a mtima , matenda a shuga , cholesterol , matenda a chiwindi, osteoarthritis , Matenda a Lyme, ndi matenda a Parkinson .
Kuonjezerapo, glutathione imatsimikiziridwa kusinthira ukalamba, kupewa khansa, ndi kusunga kukumbukira.
Ubwino wa Zaumoyo
Kusunga glutathione ndibwino kuti mukhale ndi thanzi labwino, malinga ndi lipoti la 2004 lomwe linalembedwa mu Journal of Nutrition . Olembawo amalemba kuti glutathione imathandiza kwambiri kuti chitetezo cha antioxidant chitetezedwe, kuwonongeka kwa zakudya, komanso kuwonetsa njira zambiri zamoyo (kuphatikizapo kuteteza mthupi).
Olembawo amanenanso kuti kusowa kwa glutathione kumayambitsa matenda oopsa , omwe amachititsa kukula kwa matenda ambiri (kuphatikizapo matenda a Alzheimer's, matenda a Parkinson, matenda a chiwindi, cystic fibrosis, matenda a chiwindi, khansa, matenda a mtima, sitiroko ndi shuga).
Ngakhale kuti kafukufuku wokhudzana ndi kugwiritsiridwa ntchito kwa glutathione alibe malire, pali umboni wina wosonyeza kuti glutathione ikhoza kupereka phindu linalake lopatsirana (koma kachiwiri, lingakhale chifukwa cha kuwonjezeka kwa L-cysteine monga glutathione yomwe imadulidwa mu amino acid) .
Pano pali kuyang'ana pa zifukwa zingapo zofunika kuchokera ku maphunziro omwe alipo:
Ulcerative Colitis
Matenda opweteka a m'magazi monga ulcerative colitis amadziwika ndi matenda oopsya, ndipo glutathione ndi mankhwala ofunika kwambiri m'magulu a m'mimba. Kafukufuku wa zinyama akusonyeza kuti glutathione supplementation ingathandize kuchiza ulcerative colitis. Mu kafukufuku wa 2003 wofalitsidwa mu Digestive and Liver Illness , Mwachitsanzo, asayansi adapeza kuti glutathione supplementation imakula kwambiri kuwonongeka kwa colon mu makoswe ndi colitis.
Thanzi Labwino
Poyesa makoswe, olemba a kafukufuku wa 2001 kuchokera ku American Journal of Physiology adapeza kuti kuphatikizapo kugwiritsira ntchito glutathione ndi kuphunzitsa masewera olimbitsa thupi kungathandize kulimbikitsa antioxidant mphamvu ndi kuteteza motsutsana ndi kuwonongeka kwa okosijeni ndi kuchepa kwa mtima wogwira ntchito chifukwa cha ischemia reperfusion (kubwezeretsedwa wa magazi kupita kumalo omwe kale analibe kusowa magazi).
Autism
Glutathione imasonyeza lonjezo lochiza matenda a autism spectrum, limapereka kafukufuku wochepa wofalitsidwa mu Medical Science Monitor mu 2011. Phunziroli, ana 26 (a zaka zitatu mpaka 13) ali ndi matenda a autism spectrum anapatsidwa milungu eyiti ya mankhwala ndi glutathione kupatsirana kapena kutayika (glutathione) (mtundu wa chithandizo umene umaphatikizapo kutulutsa zowonjezera zogwiritsa ntchito khungu).
Zotsatira zinasonyeza kuti glutathione zowonjezera zowonjezera zinawathandiza kuwonjezera makani a glutathione pamlingo winawake. Olemba a phunziroli amafuna kufufuza kwina ponena za kugwiritsiridwa ntchito kwa zowonjezereka za glutathione ndi zomwe zingathe kusintha zizindikiro za matenda a autism spectrum.
Khungu
Zambiri zamagetsi zomwe zili ndi glutathione zimagulitsidwa chifukwa chodzidzidzidwa khungu. Zidazi zikuphatikizapo sopo ndi ma creams. Komabe, anthu ena amatenga zowonjezereka zowonjezera khungu. Ngakhale kuti glutathione kawirikawiri imakhala njira yowonetsera kuti khungu liyeretsedwe, palibe chithandizo cha sayansi pazinthu izi.
Kugwiritsa Ntchito Zovuta ndi Zovulaza
Nthaŵi zina, akatswiri azachipatala amachititsa glutathione pogwiritsa ntchito IV . Mukapatsidwa mwachangu, glutathione amagwiritsidwa ntchito pochiza matenda monga Parkinson, matenda a atherosclerosis, ndi shuga. Kuonjezerapo, kupereka gudatione kudzera mu IV nthawi zina kumagwiritsidwa ntchito pofuna kuthana ndi zotsatira za chemotherapy , hemodialysis mankhwala, komanso opaleshoni.
Nthawi zina akatswiri a zaumoyo amajambulira glutathione pofuna kuteteza mankhwala osokoneza bongo kapena mankhwala.
Zotsatira Zotsatira
Chifukwa chosowa kafukufuku, sadziwa pang'ono za zotsatira za kugwiritsira ntchito glutathione. Komabe, pali vuto linalake kuti kugwiritsa ntchito glutathione zowonjezereka kungayambitse kupweteka ndi kupweteka. Kuonjezera apo, anthu ena akhoza kuthandizidwa ndi mavitamini (glutathione supplements) monga kuphulika.
Kumene Mungapeze
Zowonjezeka kuti zithe kugula pa intaneti, zowonjezereka za glutathione ndi mankhwala a glutathione amatha kugulitsidwa m'masitolo ambiri achilengedwe, mankhwala osungiramo mankhwala, ndi malo ogulitsa zakudya zowonjezera zakudya.
Kugwiritsa Ntchito Icho Kukhala ndi Thanzi Labwino
Zopindulitsa za mulomo wodwala glutathione supplementation zingakhale chifukwa cha kuwonjezeka kwa L-cysteine. Mavitamini ena, monga N-acetylcysteine , angapereke L-cysteine kuti ikhale yowonjezera maonekedwe a glutathione mu thupi mwa njira yotsika mtengo.
Chifukwa cha kusowa thandizo lofufuza, ndiposachedwa kwambiri kuti mulangize glutathione pa matenda alionse. Ngati mukuganiza kuti kugwiritsira ntchito glutathione kungakhale kovuta, onetsetsani kuti mufunsane ndi dokotala wanu musanayambe kulembetsa chakudya chanu. Kudziletsa nokha ndi kupewa kapena kuchepetsa kusamalidwa kosatha kungakhale ndi zotsatira zoopsa.
Zotsatira
Kern JK, Geier DA, Adams JB, Garver CR, Audhya T, Geier MR. "Kuyesedwa kwachipatala cha glutathione supplementation mu vuto la autism spectrum." Med Sci Pitirizani. 2011 Dec; 17 (12): CR677-82.
Loguercio C, D'Argenio G, Delle Delle M, Cosenza V, Della Valle N, Mazzacca G, Del Vecchio Blanco C. "Glutathione supplementation imathandiza kuwonongeka kwa okosijeni mu kupweteka koyesa." Kokani Dis Dis. 2003 Sep; 35 (9): 635-41.
Ramires PR, Ji LL. "Glutathione supplementation ndi kuphunzitsa kumapangitsa kuti munthu asamangidwe ndi ischemia-reperfusion mu vivo." Am J Physiol Mtima Circ Physiol. 2001 Aug; 281 (2): H679-88.
Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. "Glutathione metabolism ndi zomwe zimakhudza thanzi." J Nutriti. 2004 Mar; 134 (3): 489-92.
Chodziwikiratu: Zomwe zili pa tsambali zimapangidwa pazinthu zophunzitsira zokha ndipo sizilowetsamo malangizo, matenda kapena chithandizo ndi dokotala wololedwa. Sichikutanthauza kubisa zonse zomwe zingatheke, kuyanjana kwa mankhwala, zochitika kapena zotsatirapo zoipa. Muyenera kupeza chithandizo chamankhwala mwamsanga pa nkhani iliyonse yathanzi ndikufunsani dokotala musanagwiritse ntchito mankhwala osakaniza kapena kusintha kwa regimen yanu.