Kodi Udindo Wake Ndi Chiyani?
Kutupa ndi chimodzi mwa zomwe zimayambitsa zowawa, koma kodi zimagwirizana ndi ululu wa fibromyalgia ?
Udindo wa kutupa mu chikhalidwe ichi wakhala mutu wa kufufuza ndi kukangana kwazaka zambiri. Ndipotu, matendawa ankatchedwa "fibrositis," kutanthauza "kutupa kwa minofu." Komabe, patapita nthawi, kusowa kwa kutupa kunachititsa madokotala kuti aone fibromyalgia ("ulusi wa minofu ndi kupweteka kwa minofu") monga nthawi yolondola.
Zaka makumi angapo pambuyo pake, tikuyang'ana kachiwiri kutentha kwa chikhalidwe ichi, chifukwa cha ntchito yowonjezera yomwe ingagwire ntchitoyi. Mndandanda wa mafunsowa ukhoza kumvetsetsa bwino matendawa komanso njira zowonjezereka za chithandizo.
N'chifukwa Chiyani Kusokonezeka?
Madokotala anakhulupirira kuti fibromyalgia sinali matenda opweteka chifukwa sichimaoneka ngati matenda opweteka kwambiri. Zida siziwoneka zotupa kapena zotentha. Kuyesedwa kwapadera kwa zizindikiro zotupa, zomwe zimawonekera m'mwamba mwa matenda monga lupus ndi nyamakazi , nthawi zambiri zimasonyeza bwino kapena zochepa zokhazokha mu fibromyalgia. Mu 2012, ofufuza akufufuza myopathies yotupa (zowawa) zomwe zimatchedwa fibromyalgia ndi "zabodza zotchedwa myopathy."
Kuwonjezera apo, mankhwala odana ndi yotupa-onse a corticosteroids ndi a non-steroidal anti-inflammatories (NSAIDs) -makhala kawirikawiri yopanda mphamvu pa kuchepetsa kupweteka kwa fibromyalgia .
Ndiye kodi vuto la kutupa limalowa pati?
Mlandu wa Kutupa
M'zaka zaposachedwa, ofufuza aphunzira zambiri za kutupa komwe kuli kotheka pa chikhalidwe ichi.
Kumayambiriro kwa chaka cha 2017, Journal of Pain Research inafalitsa kafukufuku amene amayang'ana pa mapuloteni osiyana 92 omwe amadziwika kuti ali ndi kutupa.
Ochita kafukufuku amanena kuti ndizo "zochuluka kwambiri ... kufufuza kufotokoza kwa odwala a FM mpaka lero." Iwo anafotokoza umboni wochuluka wa kutupa. Osati kokha, koma umboni umasonyeza kutupa mkatikatikati mwa mitsempha ya ubongo (ubongo ndi mitsempha ya msana wamtsempha) komanso dongosolo.
Ntchitoyi inatsimikizira kafukufuku wakale omwe akusonyeza kuti ma molekyulu a chitetezo cha m'thupi, otchedwa cytokines , ali ndi anthu omwe ali ndi fibromyalgia. Izi zimagwirizana ndi lingaliro lakuti chikhalidwe ichi chimaphatikizapo kuchepetsa thupi.
Mchitidwe wamanjenje wamkati uli ndi chitetezo chake cha thupi, chosiyana ndi thupi lonse, ndipo phunzirolo linasonyeza kwambiri maselo aumunthu otchedwa chemokines, komanso.
Kafukufuku wa 2010 wa Genevra Liptan, MD, akusonyeza kuti zikhoza kukhala fascia-chochepetsacho chazing'ono kwambiri chomwe chimakhala ndi mkatikatikati-chomwe chimayambira mu fibromyalgia. Wofusayo amatha kunena kuti chisokonezo chachisokonezo ndi kutukumula kungakhale chomwe chimapangitsa kuti pakati pakhale mphamvu , zomwe amakhulupirira kuti ndizofunika kwambiri pa matendawa.
Kutsegula pakati kumachitika pamene dongosolo loyamba la mitsempha limakhudzidwa kwambiri ndipo limagwira mobwerezabwereza kuwonjezera, kuphatikizapo kupweteka ndi zinthu zina zomwe zimapezeka ndi mphamvu zanu, monga kuwala, phokoso , ndi fungo .
Zimakhulupirira kuti zimakhala zochepa chifukwa chazizindikiro zopweteka nthawi zonse zomwe zimabweretsa ubongo ndi msana.
Kafukufuku wa 2012 mu Neuroimmunomodulation adafufuzira mbali yothetsera kutukusira komanso kusokoneza maganizo mu fibromyalgia. Ofufuza anapeza kuti kunali kutentha kwa dziko komwe kunkawoneka kuti kumamangirizana ndi yankho lachilendo kupsinjika. Iwo sankatha kudziwa ngati kutupa kunayambitsa vuto losokonezeka maganizo kapena mosiyana.
Mu 2013, ofufuza a ku Spain omwe amatsogoleredwa ndi MD Cordero adatulutsa lingaliro lakuti kutupa mu fibromyalgia kungakhale chifukwa cholephera kugwira ntchito mu mitochondria (mbali za maselo omwe amathyola zakudya zopangira mphamvu.) Phunziro lina la 2010 la ku Spain, lofalitsidwa mu Clinical Rheumatology , anawonetsa maselo akuluakulu-omwe amamasula mankhwala opweteka poyambitsa zovuta zosiyanasiyana-pakhungu la anthu omwe ali ndi fibromyalgia.
Kuchiza Kutupa mu Fibromyalgia
Popeza kuti mankhwala opatsirana ndi kutupa-steroids ndi NSAIDs-awonetsedwa kale kuti sagwira ntchito motsutsana ndi ululu wa fibromyalgia, ndi njira ziti zomwe tingakhale nazo zowononga kutupa kwathu, ndipo mwachiyembekezo, chifukwa cha ululu wathu?
Phunziro la 2017 linapereka kuti mankhwala omwe amatchedwa dose naltrexone (LDN) angathandize kuchepetsa zizindikiro zina zotupa, zomwe zikuwoneka kuti zithandize kuchepetsa ululu ndi zizindikiro zina.
Maphunziro a Liptan a 2010 pa kutupa kwa mafuko amasonyeza kuti mankhwala othandizira pa fascia akhoza kukhala othandiza. Izi zimaphatikizapo kumasulidwa kwa myofascial ( mtundu wa minofu ) ndi kugwiritsidwa ntchito kovuta kwambiri komwe kumatchedwa Rolfing. Komabe, pakadali pano, kafufuzidwe pa mankhwalawa ndi ochepa. Ndiponso, malingana ndi zizindikiro, anthu ena omwe ali ndi vutoli sangathe kulekerera mitundu ina ya misala.
Phunziro la 2012 lomwe linafalitsidwa ku Scandinavia limasonyeza kuti masewera olimbitsa thupi a m'madzi angapangitse kuchuluka kwa cytokine mu fibromyalgia, motero kuchepa kwakukulu ndi kupweteka. (Musanayambe mtundu uliwonse wa masewera olimbitsa thupi, nkofunika kuphunzira njira yoyenera yogwiritsira ntchito fibromyalgia .)
Anthu ena omwe ali ndi fibromyalgia amanena kuti ali ndi mwayi wokhala ndi mankhwala owonjezera omwe amakhulupirira kuti kuchepa. Zida zowonjezera kutentha ndizo:
Ife sitinayambe kufufuza pa zakudya zotsutsa-kutupa kwa fibromyalgia, koma madokotala ambiri amalimbikitsa izo kuti zikhale zotupa. Chifukwa chakuti sikuti aliyense ali ndi zotupa zokhazokha, anthu amayamba kudya zakudya zochepa, kenaka kuwonjezera pa chakudya chimodzi panthawi kuti mudziwe zakudya zomwe ziri zovuta.
Mawu ochokera
Pamene tiphunzira zambiri zokhudza ntchito yotupa mu fibromyalgia, tikhoza kupeza zatsopano za mankhwala ndi mankhwala ena, ndipo izi zingayambitse njira zabwino zothandizira pa msewu.
Sitikudziwa kuti kukula kwa kutupa kuli kotani, kapena kuti ndi chifukwa kapena chikhalidwe chake. Awa ndi mafunso omwe angayankhidwe ngati mndandanda wa kufufuza ukupitiriza kufufuzidwa.
Zotsatira :,
Backryd E, Tanum L, Lind AL, Larsson A, Gordh T. Magazini ofufuzira kafukufuku. > 2017 Mar 3; 10: 515-525. lembani: 10.2147 / JPR.S128508. Umboni wa kutukusira kwachidziwitso ndi matenda opatsirana m'magulu a odwala fibromyalgia, monga momwe amayendera ndi mapuloteni ambiri a mapuloteni amagwiritsidwa ntchito ku cerebrospinal fluid ndi plasma.
Blanco I, et al. Kachipatala. 2010 Dec; 29 (12): 1403-12. Kusalongosola mopitirira malire kwa mastocytes mu zikopa za khungu za odwala fibromyalgia.
Bote ME, et al. Kusokoneza maganizo. 2012; 19 (6): 343-51. Kupsinjika maganizo / kupsinjika maganizo kwowonongeka kwa amayi omwe ali ndi fibromyalgia.
> Cordero MD, ndi al. Antioxidants & redox chizindikiro. 2013 Mar 1; 18 (7): 800-7. Kodi kutupa ndikochitika chifukwa cha mitochondrial yolimbana ndi vutoli?
> Liptan, GL. Journal of bodywork ndi kayendetsedwe ka mankhwala. 2010 Jan; 14 (1): 3-12. Fascia: Palibe chomwe chimasowa kumvetsetsa kwathu kwa matenda a fibromyalgia.