Antiinflammatories: Zowopsya ndi Kuganizira
Pamene muli ndi fibromyalgia (FMS) ndi matenda otopa ( ME / CFS ), mukhoza kutha kumwa mankhwala osiyanasiyana, kuphatikizapo mankhwala omwe mumakhala nawo. Ngakhale kuti izi zingakuthandizeni kumva ndikumagwira bwino, zingakhalenso zoopsa. Zimapindulitsa kumvetsa mankhwala omwe alipo.
Mitundu yambiri ya mankhwala ozunguza bongo amapezeka pamtengowo (OTC), ndipo ambiri mwa ife timapatsidwa mankhwala osokoneza bongo nthawi zina pa matenda athu.
Mankhwalawa ali ndi zoopsa zawo ndipo zotsatira zake zimakhala zovuta, ndipo ena akhoza kuthandizana kwambiri ndi mankhwala ena.
Imodzi mwa mitundu yowonjezereka ya painkillers ndi anti-inflammatory drugs. Mtundu wotsutsa kwambiri wotchedwa anti-inflammatories umatchedwa NSAID, umene umaimira mankhwala osagwiritsa ntchito mankhwala oletsa kutupa. OTC NSAID zowonjezereka zikuphatikizapo:
- Advil, Motrin (ibuprofen)
- Aleve, Naprosyn (naproxen)
- Bayer, Bufferin, Excedrin (aspirin)
Mankhwala awa amapezekanso ndi mphamvu zamagetsi. NSAID zokhudzana ndi mankhwalawa ndizo:
- Relafen (nabumetone)
- Feldene (piroxicam)
- Orudis (ketoprofen)
- Voltaren (diclofenac)
- Lodine (etodolac)
- Celebrex (celecoxib)
Ambiri aife timadziwa bwino ntchito za NSAID kuti tipewe kupweteka kumeneku chifukwa cha kutupa. Komabe, ma NSAID ena angachepetse ululu mwa kutseka mavitamini ena omwe ali mbali ya momwe thupi lanu limayankhira ndi zowawa zopweteka. Sizodziwikiratu ngati njirayi ili yogwirizana ndi mitundu yosautsa yachilendo yogwirizana ndi FMS .
Pachifukwa ichi, chizoloŵezi ndi madokotala ndikupereka NSAID zocheperapo ndipo m'malo mwake zimapereka mankhwala omwe amagwira ntchito pakatikati pa zamanjenje, komwe ndikumvetsa kuti zimachokera. Izi zikugwirizana ndi kafukufuku wofalitsidwa mu 2013 ya European Journal of Medicine.
Kafukufuku wina amasonyeza kuti kuvuta kumathandiza kwambiri pa ME / CFS .
Kodi FMS ndi yotupa ? Zikuwoneka kuti sizingakhale, koma phunziro lolembedwa ndi Ginevra Liptan, MD, likusonyeza kuti limaphatikizapo kutentha kwa fascia.
Mosasamala kanthu za maudindo ena omwe ali ndi kutupa, tikudziwa kuti anthu ambiri amatenga NSAID pa ululu wa FMS ndi ME / CFS, ndipo ena omwe ali ndi matendawa amatenga NSAID ku mavuto ena azachipatala omwe akuphatikizapo kutupa.
Ngozi za NSAID
Pamene mungapeze ma NSAID m'nyumba zambiri ndikugula pafupifupi kulikonse, iwo adakali ndi ngozi zazikulu.
Malingana ndi American Journal of Medicine, anthu opitirira 100,000 amamangidwa m'chipatala chifukwa cha NSAID chaka chilichonse ku US Kuwonjezera apo, 15-20,000 amafa chaka chilichonse kuchokera ku mavuto a NSAID monga zilonda zam'mimba ndi m'mimba, komanso 60 peresenti ya NSAID ogwiritsa ntchito akhoza kukhala ndi zotsatira zoyipa za kugaya.
NSAID imathandizidwanso ndi chiopsezo chowonjezeka cha kufa chifukwa cha matenda a mtima kapena kupwetekedwa mtima. Mankhwalawa angayambitse matenda a chiwindi kapena impso.
Kupeza NSAID ziwiri pamodzi kuli koopsa-kafukufuku wa 2004 wofalitsidwa mu European Journal ya Clinical Pharmacology inasonyeza kuti chinawonjezera chiopsezo cha kuvulala kwa chiwindi kapena kuperewera kwa impso ndi 500 mpaka 100 peresenti pogwiritsa ntchito NSAID imodzi.
Kugwiritsa ntchito nthawi yaitali, monga momwe mungayembekezere ndi matenda aakulu, kungapangitse ngozizi.
Zina mwa mavuto omwe amachokera ku ntchito ya NSAID angakhale chifukwa cha maganizo a anthu pa mankhwala osokoneza bongo. Angaganize kuti sali ofunika kapena owopsa choncho musanene kuti akugwiritsa ntchito kwa dokotala kapena mankhwala. Ndikofunika kwambiri kuti akatswiri azaumoyowa adziwe zonse zomwe mukuzitenga, kuphatikizapo mankhwala osokoneza bongo komanso owonjezera zakudya, kuti athe kukuthandizani kupewa mavuto aakulu.
NSAID Zotsatira Zotsatira & Kuyanjana
Kuphatikiza pa zoopsa zapamwambazi, NSAIDs zingayambitse zotsatira zambiri. Zowonjezeka kwambiri ndi izi:
- Nausea
- Kuthamanga
- Kutsekula m'mimba
- Kutsekedwa
- Amachepetsa njala
- Rash
- Chizungulire
- Mutu
- Kugona
Zina mwa zotsatira zake (mavuto osokonekera, umutu, umutu, kugona) zimakhalanso zizindikiro za FMS ndi ME / CFS. Mukayamba kutenga NSAID yatsopano, ndikofunika kuti muzindikire kusintha kulikonse komwe kungakhale chifukwa cha mankhwala.
NSAID zingagwirane ntchito molakwika ndi mankhwala ena ambiri, choncho onetsetsani kuti mukuyankhula ndi dokotala wanu ndi wamankhwala za mankhwala anu onse.
Chifukwa chakuti NSAID zimachepetsa mphamvu ya magazi kuti ikhale yophimba, zingakhale zoopsa kuziphatikiza ndi anticoagulants (ochepa magazi) monga Coumadin (warfarin).
Ngati mukuchiritsidwa (kuthamanga kwa magazi), muyenera kudziwa kuti NSAID zingapangitse mankhwala anu kukhala opanda mphamvu.
Kuchepetsa Vuto Lanu
Malingana ndi FDA, kuteteza thanzi lanu muyenera kugwiritsa ntchito NSAID monga momwe mwafunira, pa mlingo wotsika kwambiri, komanso kwa nthawi yochepa momwe mungathere.
Pamene kupweteka kwanu kuli kosatha, malangizo otsirizawa ndi ovuta kutsatira. Onetsetsani kuti munenepo kuwonjezeka kulikonse kwa zotsatirapo kwa dokotala wanu. Dokotala wanu angafune kuyang'anira zizindikiro za thanzi la chiwindi ngati mutenga NSAID nthawi yayitali.
Kusuta ndudu ndi kumwa mowa kungapangitse ngozi yanu ya zilonda zamtundu wa NSAID kapena mavuto ochotsa magazi, zomwe zonsezi zingayambitse popanda kuchenjeza ndipo zingakhoze kukupha. Onetsetsani kuti dokotala akudziwa za kusuta kwanu ndi kumwa mowa.
Mawu ochokera
Inu ndi dokotala wanu muyenera kusankha pamodzi ngati NSAID zili zoyenera kwa inu, malingana ndi zomwe mumapeza, zizindikiro, moyo wanu wonse ndi moyo wanu. Ndikofunika kuzindikira kuti NSAID imodzi ikhoza kukuyenderani bwino kuposa ena, kotero zingatenge kuyesera ndi mankhwala osiyanasiyana kuti zikwaniritse zotsatira zabwino.
Ngati simukumva kuti NSAID zathandiza kuchepetsa kupweteka kwanu, lankhulani ndi dokotala wanu za njira zina zomwe zingatheke ndipo yesetsani kuopseza phindu.
Zotsatira:
Carruthers BM, ndi. al. Journal za mankhwala amkati. 2011 Oct; 270 (4): 327-38. lembani: 10.1111 / j.1365-2796.2011.02428.x. Myalgic encephalomyelitis: Zolinga za mgwirizano padziko lonse.
Lowani F, ndi. al. Magazini ya ku Ulaya ya mankhwala opatsirana mankhwala. 2004 Jun; 60 (4): 279-83. Mgwirizanowo pakati pa kugwiritsidwa ntchito kwa mitundu yosiyanasiyana ya NSAID komanso njira zambiri zomwe zingawononge mankhwala osokoneza bongo. Chidziwitso / chosakhala chiwerengero kuchokera ku French Pharmacovigilance system database.
Kovac SH, et. al. Arthritis ndi rheumatism. 2008 Feb 15; 59 (2): 227-33. Mgwirizanowo wa umoyo wokhudzana ndi thanzi labwino ndi kugwiritsa ntchito mankhwala awiri ndi mankhwala osagwiritsa ntchito mankhwala.
Liptan GL. Journal of bodywork ndi kayendetsedwe ka mankhwala. 2010 Jan; 14 (1): 3-12. Fascia: chosoweka chikugwirizanitsa kumvetsa kwathu za matenda a fibromyalgia.
Wolfe F, et al. Magazini ya ku Europe ya ululu. 2013 Apr; 17 (4): 581-6. Mapuloteni ambiri a mankhwala ozunguza bongo amagwiritsa ntchito komanso amagwiritsidwa ntchito moyenera mu fibromyalgia.