Asayansi akuyesetsabe kumvetsetsa chomwe chimayambitsa matenda a Alzheimer's . Padakali pano, zimathandiza kumvetsetsa zizindikiro za Alzheimer's - mapangidwe ndi makoswe - ndizifukwa zomwe zimakhudza mwayi wa munthu kuti adziwe matendawa.
Mipata ndi Zingwe
Matenda a Alzheimers amadziwika ndi mapangidwe a mapuloteni mu ubongo.
Ngakhale izi sizingakhoze kuwerengedwa mwa munthu wamoyo, kufufuza kwakukulu kwa autopsy kwavumbula chodabwitsa ichi. Zomangamanga zikuwonetsera m'njira ziwiri:
- Miphika - mapuloteni a puloteni beta-amyloid omwe amasonkhanitsa pakati pa maselo a mitsempha
- Makoswe - ma depositi a tau omwe amasonkhanitsa mkati mwa maselo a mitsempha
Asayansi akuphunziranso mmene mapulaneti ndi mabala amathandizira matenda a Alzheimer's. Mfundo imodzi ndi yakuti amachititsa kuti maselo a mitsempha ayambe kulankhulana, zomwe zimapangitsa kuti maselo akhale ovuta.
Kuthamangitsidwa kwawonetsa kuti anthu ambiri amapanga zipika ndi zovuta pamene akukalamba, koma anthu omwe ali ndi Alzheimer amakula kwambiri kuposa omwe sakhala ndi matendawa. Asayansi samadziwa chifukwa chake anthu ena amakula kwambiri poyerekeza ndi ena. Komabe, zifukwa zingapo zomwe zimayambitsa matenda a Alzheimer's disease zakhala zikuwululidwa.
Zoopsa za Alzheimer's
- Zaka : Kukalamba ndi nambala imodzi yomwe imayambitsa matenda a Alzheimer's . Mmodzi mwa anthu asanu ndi atatu (8) opitirira zaka 65 ali ndi matenda a Alzheimers, ndipo pafupifupi mmodzi mwa anthu awiri aliwonse oposa zaka 85 ali ndi Alzheimer's. Mpata wa kupezeka ndi Alzheimer pafupifupi zaka ziwiri zitatha zaka 65.
- Mbiri ya Banja : Anthu omwe ali ndi kholo kapena mchimwene amene adayambitsa matenda a Alzheimer amakhala odwala kaŵirikaŵiri katatu kuti akhale ndi matenda kusiyana ndi omwe alibe mbiri ya Alzheimer's. Ngati oposa mmodzi wapafupi adakhudzidwa, chiopsezo chikuwonjezereka kwambiri.
Asayansi apeza mitundu iwiri ya majini yomwe imakhudzidwa ndi vutoli la banja. Yoyamba imaganiziridwa kuti ndi "jini yachangu ," ApoE 4 , yomwe imapangitsa mwayi wopanga Alzheimer's, koma sizikutsimikizira izo. Kuphatikiza pa ApoE 4, asayansi amaganiza kuti pangakhale zamoyo khumi ndi ziwiri zoopsa zomwe zingapezeke.
Mtundu wachiwiri wa jini ndi "jini yotengera" ndipo ndi wochuluka kwambiri kusiyana ndi majeremusi owopsa. Zamoyo zamtunduwu zimapezeka m'mabanja ochepa chabe padziko lonse lapansi. Ngati jini ya deterministic inalengedwa, munthuyo mosakayika amakhala ndi Alzheimer's, mwinamwake ali wamng'ono kwambiri.
- Zochitika Zamoyo : Ngakhale kuti mbiri yakale ndi banja sizingatheke, asayansi azindikiranso zinthu zambiri zomwe zimakhala ndi moyo zomwe zingakhudze chiopsezo cha munthu kuti adwale matenda a Alzheimer. Kulumikizana kwapezeka pakati pa kuvulaza mutu wamkuntho ndi kupititsa patsogolo kwa Alzheimer's , kotero iwo omwe amachititsa chitetezo monga kuvala mikanda yapamwamba ndi kusagwira nawo ntchito omwe ali ndi chiopsezo chachikulu chogwera ali opindulitsa.
Umboni umakonzedwa kuti apititse patsogolo masewero olimbitsa thupi komanso zakudya zabwino kuti athetse vuto la Alzheimer. Kupewa fodya , kuchepetsa kumwa mowa mopitirira muyeso , kugwira ntchito mwakhama, komanso kuchita zinthu zowonongetsa zaumunthu zakhala zikuwonetsedwanso kukhala ndi chitetezo choteteza matenda a Alzheimer's.
Pomaliza, pali mgwirizano wamphamvu pakati pa thanzi labwino ndi ubongo wa ubongo . Anthu omwe ali ndi matenda a mtima kapena zochitika zofanana ali pangozi yochepetsetsa matenda a Alzheimer's or other dementia ngati omwe ali ndi mavuto a mtima.
Zotsatira:
"Matenda a Alzheimer: Kutsegula chinsinsi." National Institute on Aging. August 29, 2006.
"Kafukufuku wa Alzheimer's Causes and Factors." Gulu la Nsomba za Alzheimer's Research Foundation. May 1, 2003. http://www.alzinfo.org/research/alzheimers-research-on-causes-and-risk-factors
"Chibadwa, zamoyo, ndi crossword puzzles: Kodi matenda a Alzheimer angalephereke?" National Institutes of Health. 2005.
-Imasinthidwa ndi Esther Heerema, MSW, Expert's Alfheimer's Disease Expert