Hyperalgesia ndikumva kupweteka kwambiri komwe kumafala ku fibromyalgia (FMS) ndi matenda otupa aakulu ( ME / CFS ). Mu fibromyalgia, ndi chinthu chofunika kwambiri chomwe chimatanthauzira chikhalidwecho.
Mwachidule, pamene muli ndi hyperalgesia, thupi lanu limapweteka kwambiri kuposa momwe liyenera kukhalira. Izi nthawi zambiri amatchedwa "kutembenuza voliyumu" pa ululu.
Icho ndi chenichenicho, chochitika cha thupi osati chifukwa cha matenda a maganizo monga hypochondria. Sikuti ndi zotsatira za munthu "kupanga zinthu zambiri popanda kanthu," monga momwe anthu ena angakhulupirire.
Mapulogalamu apamwamba a ubongo amasonyeza kuti izi zimapweteka kwambiri, komanso malo opweteka a ubongo akuwonekera kwambiri kwa anthu omwe ali ndi matenda omwe ali ndi hyperalgesia kuposa omwe alibe. Izi zikusonyeza kusiyana kwa thupi - osati maganizo - zowawa za ululu.
Mwachitsanzo, ngati munthu wamba angawonetsere kumverera kwapadera pa zisanu pa msinkhu wopweteketsa, wina yemwe ali ndi hyperalgesia akhoza kuyesa izo pa zisanu ndi ziwiri kapena zisanu ndi zitatu.
Kuwonjezeka kwa ululu chifukwa cha hyperalgesia kungatheke ku mbali zina za thupi kapena zingathe kufalikira.
Mbali yosamvetsetseka ya hyperalgesia ndi yakuti sichimayambitsa kupweteka, koma chimangowonjezera. Munthu ayenera kukhala ndi ululu kuchokera ku gwero lina musanakhale hyperalgesia.
Kupweteka kochuluka chifukwa cha chizindikiro ichi nthawi zina chimapangitsa kusiyana pakati pa munthu kukhala wogwira ntchito komanso kukhala wofooka ndi matenda awo.
Ngakhale zikuwoneka kuti zikutsutsana, kupweteka kwa opioid (narcotic) kumachepetsa monga Vicodin (hydrocodone-acetaminophen) ndi OxyContin (oxycodone) nthawi zina, pogwiritsa ntchito nthawi yaitali, zimayambitsa hyperalgesia.
Izi zimatchedwa hyperalgesia. Pazochitikazi, mankhwala amene anthu amadalira kuti azikhala bwino akuwakhumudwitsa kwambiri. Njira yothetsera vutoli ndiyo kusiya kumwa mankhwalawa.
Hyperalgesia ndi Syndromes Pakati pa Chisomo
Matenda a hyperalgesia ndiwo amodzi omwe amachititsa matenda omwe amatchedwa syndromes , omwe amachititsa kuti FMS, ME / CFS, matenda opwetekedwa mtima , ziwalo zosapumitsa miyendo , ndi zina zambiri. Amagwirizananso ndi zinthu zina zotupa ndi kuwonongeka kwa mitundu ina ya mitsempha.
Kuonjezerapo, hyperalgesia ikhoza kuyankhidwa ndi maselo a chitetezo cha mthupi otchedwa pro-inflammatory cytokines , omwe thupi lanu limatulutsidwa poyankha matenda. Mapuloteni otchedwa inftomatory cytokines amaphunzitsidwa kukhalapo nthawi zina za ME / CFS. (Sindikudziwikanso ngati ndi chifukwa cha matenda opitilirapo kapena chifukwa cha chitetezo cha chitetezo chokhazikika.)
Ambiri mwa mankhwalawa kwa FMS ndi ME / CFS amayenera, makamaka mbali, kuchepetsa hyperalgesia. Izi zimaphatikizapo mankhwala oletsa anti-depressant (monga Cymbalta , Savella , ndi amitriptyline ) komanso mankhwala osokoneza bongo (kuphatikizapo Lyrica ndi gabapentin .)
Mtundu uwu umapweteka ndi wosiyana siyana, womwe umapezeka mu FMS ndikupezeka nthawi zina za ME / CFS.
Allodynia ndikumva kupweteka kwa chinthu chomwe sichimakhala chopweteka, monga kukhudza kuwala. Nthaŵi zambiri Allodynia amatchedwa "ululu wa pakhungu," chifukwa nthawi zambiri amasonyeza kuti amachititsa kuti thupi liziyenda kwambiri.