Popeza buku lakuti "The Arthritis Cure" linagulitsidwa m'mabitolo osindikiza mabuku m'dziko lonselo mu 1997, madokotala, madokotala, ndi odwala matenda a nyamakazi kawirikawiri akhala akufunsidwa maganizo awo a glucosamine ngati mankhwala a nyamakazi . Mawu akuti "machiritso" omwe ali mutu wa bukuli adakweza chiyembekezo cha ambiri omwe akudwala matendawa.
Momwe Glucosamine Amagwirira Ntchito
Glucosamine amapezeka pamwamba kwambiri m'magulu.
Zakhala zikudziwika kuti glucosamine imalimbikitsa mapangidwe a cartilage omwe ndi ofunikira kukonza limodzi. Zanyama zamtundu, oral glucosamine sulphate imathandizira kutupa, makina a nyamakazi, ndi matenda a immunological-othetsera matenda a nyamakazi, ngakhale kuti ndi ochepa kwambiri kuposa indomethacin ndi mankhwala ena oterowo.
Nthaŵi zina glucosamine amagwiritsidwa ntchito kuphatikizapo chondroitin sulphate monga mankhwala a nyamakazi. Chondroitin sulphate imapezedwanso mu kanyumba. Chondroitin sulphate imati imapangitsa kuti mamasukidwe a viscosity ayambe kugwiritsidwa ntchito, imachititsa kuti kanyumba konzekeretse kayendedwe kake, ndipo chimachepetsa michere yomwe imaphwanya khungu.
Zakudya Zakudya
Glucosamine imagulitsidwa ku United States monga chakudya chowonjezera. Dietary Supplement Health and Education Act yomwe inaperekedwa mu 1994 ndi Congress ikulola kugulitsidwa kwa mankhwala omwe amati akukhudza kapangidwe ka ntchito kapena thupi la thupi monga "chakudya chowonjezera" popanda chivomerezo cha bungwe lirilonse la boma.
Kulembapo ziyenera kuphatikizapo chotsutsa kuti chipangizocho sichiyankhidwa ndi FDA ndipo mankhwalawo sali oyenerera kuti adziwe, asamalidwe, kapena ateteze matenda aliwonse. Glucosamine imapezeka m'ma pharmacies komanso m'masitolo ogulitsa zakudya monga sulfate, hydrochloride, n-acetyl, kapena salt yamchere.
Maphunziro a Zipatala
Kafukufuku wochepa wa nthawi yayitali wanena kuti glucosamine ndi yothandiza kuthetsa ululu kwa odwala osteoarthritis ndi kuwonjezera kuyendayenda kwawo .
Kuyesedwa kwapakati pa milungu iwiri ya odwala 252 osteoarthritis of knee anapeza oral glucosamine sulfate 500 mg. katatu patsiku kumapindulitsa kwambiri kuposa maloboti ochotsera zizindikiro.
Chiyeso china cha milungu iwiri yokhala wakhungu cha odwala 200 omwe ali ndi matenda a mitsempha ya bondo anawulula 500 mg. ya glucosamine sulphate yomwe imathandiza kuthetsa zizindikiro monga ibuprofen 400 mg. katatu pa tsiku, pambuyo pa sabata yachiwiri.
Mu phunziro la masabata asanu ndi atatu osapenya la odwala 40 odwala matenda a osteoarthritis, glucosamine sulphate 500 mg. katatu patsiku pamlomo kunali kothandiza monga ibuprofen 400 mg. katatu patsiku kuti athetse ululu musabata milungu iwiri yoyamba. Mu mauthenga onse glucosamine amalekerera bwino ndi chiwerengero cha ziwalo za m'mimba chosapitirira kuposa placebo.
Maphunzirowa, ngakhale kupereka zotsatira zabwino sanawoneke ngati maphunziro opangidwa bwino. Maphunziro okonzedweratu ayenera kuchitidwa pogwiritsa ntchito owerengeka okwanira pa nthawi yokwanira, chaka chimodzi, ndi ofufuza odziwa bwino ntchito, pogwiritsa ntchito njira zowonetsera komanso zowerengera zomwe zingawononge ngati zotsatira zake ndizowongolera. Maphunzirowa anakumana ndi ziwerengero zochepa zomwe adazichita ndipo anachitidwa odwala ochepa kwambiri.
Malingana ndi kafukufuku wa 2004 ku Canada, odwala okwana 137, palibe kusiyana kwakukulu komwe kunapezeka pakati pa chiwerengero cha anthu omwe adalowa mu malo a placebo ndi gulu la glucosamine.
Pamsonkhano wa ACR wa 2005, zotsatira za mayesero awiri a glucosamine zinaperekedwa. GAIT (Glucosamine / Chondroitin Arthritis Testing Intervention Trial) inadalitsidwa ndi NIH ndipo yapangidwa kuti ipange chitetezo ndi kuthandizira ndi glucosamine, chondroitin, kutengedwa padera kapena palimodzi, ndi KUTENGEDWA (Glucosamine Unum In Die Efficacy) chinali chiyeso cha ku Ulaya. Zotsatira zowonjezera zinkasonyeza kuti glucosamine inapereka chithandizo chambiri kuposa acetaminophen.
GAIT zotsatira zimasonyeza kusakaniza kwa glucosamine ndi chondroitin kuli bwino kuposa placebo koma mapindu amaoneka kuti amadalira kuuma kwa ululu. Odwala omwe ali ndi ululu wamagazi ofooka, mafupa a glucosamine chondroitin sanali ogwira ntchito kwambiri kuposa placebo.
- Zotsatira za Glucosamine Zotsatira Zowonekera pa 2005 ACR Meeting
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Kutsiliza
Chigwirizano ndi chakuti glucosamine ndi chondroitin zowonjezereka zimatha kuchepetsa ululu kwa odwala ena a osteoarthritis. Madokotala ambiri tsopano akukhulupirira kuti kuli koyenera kuyesa mankhwala owonjezera a osteoarthritis. Iwo amawoneka kuti ali otetezeka, koma madokotala akuchenjeza odwala kuti ubwino ndi mphamvu ya glucosamine ndi chondroitin zimasiyana chifukwa cha kusagwirizana. Ngati mukufuna kuwayesa, gulani zinthu zamtengo wapatali kuchokera ku gwero lolemekezeka.
Zotsatira:
Buku Limene Limalonjeza Chithandizo, Matenda a Nyamakazi Masiku Ano, May-June 1997
Yesani Glucosamine kwa OA, Arthritis Today, July-August 1998
Glucosamine for Arthritis, 1997 Mlembi Wamankhwala, Home Page Quackwatch