N'zochititsa chidwi kuti anthu pafupifupi 27 miliyoni omwe ali ndi hypothyroidism amatha kupezedwa ndi matenda a fibromyalgia. Zonsezi zimakhala ndi zizindikiro zambiri zofanana, kuphatikizapo kutopa, kutopa, kuvutika maganizo, ubongo wa ubongo , ndi kupweteka kwa minofu ndi kuphatikiza .
Akatswiri ena amanena kuti mofanana ndi matenda ambiri a hypothyroidism ku United States, fibromyalgia ndi nthendayi yokha.
Ena amati gulu la zizindikiro za fibromyalgia kwenikweni ndi zizindikiro za hypothyroidism yokha. Koma palibe kukayikira kuti pali zambiri zomwe zimachitika pakati pa zikhalidwe ziwirizi.
Kumvetsa Fibromyalgia
Fibromyalgia imatchedwanso matenda a fibromyalgia (FMS), fibromyositis, fibrositis, ndi myofibrositis. Fibromyalgia imadziwika ndi kupweteka komanso kupweteka kwa thupi, kutopa, ndi kutopa mukatha kugona komanso mutachita khama.
Fibromyalgia imakhudza pafupifupi anthu mamiliyoni asanu ndi atatu ku US, makamaka makamaka kwa amayi otha msinkhu. Kawirikawiri, fibromyalgia imabweretsa akazi kasanu ndi kawiri kuposa amuna.Amadzimadzi amatuluka pakati pa zaka zapakati pa 20 ndi 55, komabe vutoli likhoza kupezedwa muunyamata. Pakati pa anthu onse, akuti anthu 3 mpaka 6 peresenti ya anthu ambiri, kuphatikizapo ana, amakumana ndi zifukwa zomveka zogwiritsira ntchito matenda a fibromyalgia.
Izi zikhoza kupanga fibromyalgia moŵirikiza kaŵirikaŵiri monga nyamakazi ya nyamakazi .
Zizindikiro za Fibromyalgia
Zizindikiro zina za fibromyalgia ndizo:
- Kumva ululu , kuyaka, kupweteka, ndi kupweteka m'thupi
- Mutu, tsitsi la scalp, ululu kumbuyo kwa chigaza
- Ululu pa khosi, paphewa, mapewa ndi mapewa
- Ululu m'chiuno, pamwamba pa matako, kunja kwa mchiuno chapansi, pansi pamako, ndi pelvis
- Ululu pamadzulo ndi malo otupa
- Kutopa, kusagona mopanda mpumulo , kudzuka kutopa, kuuma kwa m'mawa
- Kusagona, kugwedezeka, kuvutika kugona, kapena kugona tulo mwamsanga
- Zochitika za Raynaud (kumene manja anu akumverera ozizira, otopa, kapena kutembenuzira buluu, pamene kusintha kwa kutentha kumasintha)
- Matenda owopsa a m'mimba, kutsekula m'mimba, kudzimbidwa, kupweteka, kupweteka
Kuzindikira kwa Fibromyalgia
Kufufuza kovomerezeka kumatsimikiziridwa pogwiritsa ntchito American College ya Rheumatology yoyenera ya fibromyalgia:
____________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________ Ululu uyenera kukhala kumbali ya kumanzere kwa thupi ndi kumanja, ndi ululu pamwamba ndi pansi pa m'chiuno. Mphepete mwachiberekero, chifuwa chamkati, thoracic msana kapena kupweteka kwapweteka kumakhalaponso.
Kuwonjezera apo, ululu pa malo khumi ndi asanu ndi anayi ndi asanu ndi atatu (18) ofotokozera , omwe akuphatikizapo:
____ Kumalo komwe minofu ya khosi imamangirira kumunsi kwa chigaza, mbali za kumanzere ndi kumanja (Occiput)
____ Midway pakati pa khosi ndi mapewa, mbali zamanzere ndi zamanja (Trapezius)
____ Minofu kumanzere kumanzere ndi mbali yamkati, mkati kumanzere ndi kumanja (Supraspinatus)
____ 2 masentimita pansipa fupa lamphongo kumbali ya kumanzere ndi mikono yolondola (Otsatira epicondyle)
____ Masankhulidwe akumwamba otsika ndi kumanja (Gluteal)
__________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
____ Pamwamba pamadzulo akumanzere ndi kumanja mkati
____ Pakhosi lakuya kutsogolo, mbali ya kumanzere ndi kumanja (Chitseko chochepa)
____ Kutsetsereka kumtunda kwa fupa, kumanzere ndi kumanja (nthiti yachiwiri)
Fibromyalgia ndi kutopa katswiri wotchedwa Jacob Teitelbaum , MD, wolemba wa From Fatigued to Fantastic , amatanthauzira momveka bwino. Amakhulupirira kuti ngati wina nthawi zambiri amatha kufotokoza za fibromyalgia, ndi zizindikiro kuphatikizapo kutopa kopanda kufotokoza, kuphatikizapo zizindikilo ziwiri kuchokera mu ubongo wa ubongo, kusokonezeka kwa tulo, kukhumudwa kwambiri, kutaya thupi, ndi / kapena matenda opatsirana kapena achizolowezi, kapena kumva ngati chimfine, ndiye ziyenera kuganiziridwa bwino.
The Hypothalamic Connection
Dr. Teitelbaum amakhulupirira kuti pachimake cha kutsekemera kwa chithokomiro ndi fibromyalgia ndi vuto ndi kusokonekera kapena kuponderezedwa kwa mbuye wa ubongo mu ubongo wotchedwa hypothalamus.
Dr. Teitelbaum ...
Matendawa amachititsa tulo, mahomoni anu, malamulo a kutentha, komanso njira yodzikweza yaumadzi (mwachitsanzo - kuthamanga kwa magazi, kuthamanga kwa magazi, ndi kuyenda kwa chakudya kudzera m'mimba yanu). Ichi ndi chifukwa chake simungathe kugona, muli ndi kutentha kwakukulu, mumakhala wolemera, ndipo (chifukwa kugona kovuta kumayambitsa matenda osokoneza thupi) mumakhala ndi matenda osiyanasiyana. Chifukwa chokhalira osagwiritsidwa ntchito, chokhacho chimatha chifukwa cha zizindikiro zambiri. Ndikuganiza kuti mavuto ndi "zitsulo zamagetsi" m'maselo anu (otchedwa mitochondria) nthawi zambiri amachititsa kuti hypothalamic chisokonezeko.
Chiyanjano cha Chithokomiro ndi T3
Ngati muli ndi matenda a chithokomiro omwe ali ndi zizindikiro za fibromyalgia, muyenera kuganiziridwa ndi dokotala ali ndi luso lachidziwitso, kaya ali wokwanira kapena MD wothandizira, internist kapena rheumatologist.
Ndipo, ngati muli odwala fibromyalgia, ndiyeneranso kukumba mwakuya kuti mudziwe ngati muli ndi vuto la chithokomiro lomwe likhoza kukuthandizani-kapena ngakhale kuyambitsa-zizindikiro zanu za fibromyalgia.
Anthu ambiri amakhala ndi vuto la chithokomiro la TSH kuti aone ngati ali ndi vuto la chithokomiro, koma Dr. John Lowe, yemwe ankapita ku Fibromyalgia Research Foundation ndipo analemba buku lakuti The Metabolic Treatment of Fibromyalgia , anafunsa zomwe amachitcha kuti " . "
- Chokhacho chokhacho cha vuto la kutentha kwa mahomoni ndi hypothyroidism
- odwala okha omwe ali ndi hypothyroidism "malinga ndi zotsatira za labu" ayenera kuloledwa kugwiritsa ntchito hormone ya chithokomiro
- wodwala wa hypothyroid ayenera kuloledwa kugwiritsa ntchito T4 (levothyroxine) ndi
- mlingo wa wodwalayo sayenera kupewera chithokomiro chothandizira kutentha kwa hormone (TSH).
Dr. Lowe anayenera kutsutsana ndi malingaliro awa monga gawo lake la khama lake kuti aphunzire zambiri za mankhwala osagwiritsidwa ntchito ndi fibromyalgia. Chotsatira chake chinali chithandizo cha mankhwala chotsatira pa zomwe anapeza kuti zizindikiro zosagwirizana ndi mankhwala a hypothyroidism ndi fibromyalgia kwenikweni ndi umboni wosagwidwa kapena kutsekedwa pogwiritsa ntchito hypothyroidism , kapena kutetezedwa kwapadera kwa mahomoni a chithokomiro.
Mbali yapadera ya Dr. Lowe's theories inali kuvomereza kuti wodwala amene ali ndi maselo amatha kusokoneza mahomoni a chithokomiro koma ali ndi zizindikiro ndi zizindikiro za hypothyroidism. Komabe, adapeza kuchokera ku zokambirana zake ndi akatswiri ena ofufuza za fibromyalgia / CFS, omwe ambiri samadziwa njira zoterozo. Iye wanena kuti:
Kwa iwo, ngati wodwala ali ndi mlingo wachibadwa wa TSH , makamaka ngati zizindikiro za wodwalayo sizikuyenda bwino ndi mankhwala ena a T4 (levothyroxine), matenda ake sangathe kugwirizana ndi njira iliyonse yowonongeka. Kafukufuku waposachedwapa wamasayansi, wasonyeza kuti chikhulupiriro chimenechi ndi chonyenga.
Ngati muli ndi hypothyroidism , ndizofala kuti mukhale ndi zizindikiro zakuda za fibromyalgia monga kupweteka kwa minofu / mapiritsi, mabala, ndi kusokonezeka kugona. Malinga ndi Dr. Lowe, madokotala ochiritsira amakumana ndi zizindikiro zatsopano kapena zowonongeka monga umboni wakuti palinso vuto lina lofanana ndi fibromyalgia kuphatikizapo vuto la chithokomiro . Komabe, Dr. Lowe anatanthauzira kuti monga umboni wakuti wodwalayo anali kusonyeza umboni wa hypothyroidism ochepetsedwa :
Pamene vuto la mahomoni la chithokomiro limacheperachepera, chiwerengero cha ziphuphu zimakhudzidwa ndi kukula kwa zizindikirozi zimakula. Wodwala amakhala ndi vuto losowa kwambiri monga chiwerengero chowonjezereka cha zizindikiro za kuuma kwakukulu. Kawirikawiri, odwalawa amafunikira mlingo woyenera kapena mahomoni a chithokomiro kuti awuluke ku zizindikiro zawo zonse.
Dr. Lowe amakhulupirira kuti kugwirana mwamphamvu kwa zomwe zimatchedwa "zachibadwa" sizisonyeza ngati wodwalayo ali ndi T3 ( circulation hormone) pamasom'manja, omwe amapangidwa ndi mbali ya chithokomiro, wa T4 hormone kupita ku T3) kuti akhale ndi kagayidwe kake ka maselo m'maselo. Kafukufuku wake adawonetsa kuti mankhwala oyenera komanso oponderezedwa nthawi zambiri amathandiza kuthetsa mavuto omwe akukhudzidwa kwambiri. T4 kutembenuka kwa T3 kungakhale kovuta, kotero kuti wodwala ali ndi msinkhu wachibadwa wa TSH sichikutanthauza kuti thupi lake limakhala lokhalitsa.
Malingana ndi Dr. Lowe, kafukufuku wina anasonyeza kuti mankhwala omwe amachititsa kuti TSH ikhale yovuta kwambiri, amachepetsa mosavuta odwala ambiri a cholesterol, koma miyezo ya TSH-suppressive inachepetsa kwambiri.
Malipoti ambiri ofalitsidwa ndi maphunziro athu amasonyeza kuti chiwerengero cha TSH sichigwirizana ndi mayesero osiyanasiyana a minofu ya metabolism. Dr. Lowe akuwona izi ndi zofunika chifukwa kupanga minofu yowonongeka bwino ayenera kukhala cholinga cha mankhwala onse ndi odwala hypothyroid. Pamene wodwala wa hypothyroid amangokhala mlingo wa T4 womwe umasunga TSH mkati mwake , kuyesa kudzapereka umboni wa kusagwirizana kwa thupi m'matumbo ambiri.
Akatswiri ena amafufuza kuti mahomoni a chithokomiro asatengedwe ngati mankhwala othetsera matenda a fibromyalgia kapena CFS. Malingana ndi Dr. Lowe, "m'malo" monga momwe ochita kafukufuku amavomerezera sagwira ntchito chifukwa kumangotanthawuza kumagwiritsa ntchito T4 yokha kuti TSH ikhale yoyenera . Ankaona kuti sikunali kokwanira kuti athetsere ambiri odwala hypothyroid ku zizindikiro zawo.
Anakhulupiriranso kuti kuganiza kuti mankhwala omwe amachititsa kuti T4 athetsere mankhwalawa ndi okhawo amene amavomereza kuti mankhwalawa amathandiza kuti asayansi ena asamvetsetse chifukwa cha odwala fibromyalgia ambiri. Dr. Lowed amakhulupirira kuti kuphatikiza kwa T4 ndi T3 kumagwira ntchito bwino kuposa T4 yekha ndi odwala hypothyroid , ndipo nthawi zina T3 yekha amagwira ntchito bwino. Dr. Lowe adapeza kuti pamene odwala matenda a hypothyroid ankachiritsidwa ndi T4 choyamba, pang'onopang'ono akuwonjezera mlingo, ngati iwo sanagwire ntchito zambiri kapena ayi, odwala anasinthidwa ku T3.
T4 okha ndizosauka kwa odwala ambiri hypothyroid fibromyalgia, ndipo n'kopanda phindu kwa odwala fibromyalgia omwe amatha kuteteza mahomoni a chithokomiro. Ambiri mwa odwalawa, omwe amapanga pafupifupi 44 peresenti ya odwala fibromyalgia malinga ndi maphunziro athu, amapindula ndi mayesero akuluakulu a T3. Ochepa chabe a hypothyroid fibromyalgia odwala amakhala osangalatsa kwambiri pogwiritsa ntchito T4 okha.
Mawu ochokera
Ngati muli ndi hypothyroidism ndi zizindikiro zomwe zimatanthauza fibromyalgia, kapena muli ndi fibromyalgia, mungafune kulingalira kuwona dokotala ali ndi luso muzochitika zonsezi, omwe amawawona ngati akugwirizana. Chiyambi chabwino chopeza dokotala woyenera ndi pa webusaiti ya bungwe la National Fibromyalgia Association ndi National Fibromyalgia & Chronic Pain Association
Zotsatira:
> Haliloglu S et al. "Fibromyalgia kwa odwala omwe ali ndi kachilombo koyambitsa matenda a chithokomiro: kufalikira komanso kugwirizana ndi matenda." Clin Rheumatol. 2017 Jul; 36 (7): 1617-1621. lembani: 10.1007 / s10067-017-3556-2. Epub 2017 Feb 7.
> Lowe, John. "Mankhwala Opatsirana a Fibromyalgia." McDowell Publishing Company; 2000.
> Nishioka K, et al. "Kukula kwakukulu kwa anti-TSH receptor antibody mu matenda a fibromyalgia." Int J Rheum Dis. 2017 Jun; 20 (6): 685-690. lembani: 10.1111 / 1756-185X.12964. Epub 2016 Nov 30.
> Selmi C et al. "Msonkhano wa pachaka wa ACR wa 2014: diso la mbalame likuwona kuti munthu akudziimira yekha mu 2015." Odzidzimutsa Rev. 2015 Jul; 14 (7): 622-32. lembani: 10.1016 / j.autrev.2015.03.003. Epub 2015