Mukadzuka Mutatopa
Chinthu chofunika kwambiri cha matenda aakulu ( ME / CFS) ndi kugona kwabwino komwe sikulepheretsa kutopa. Zimatchedwa kugona kosabwerera kapena kosabwereza. Ziribe kanthu kuchuluka kwa anthu omwe ali ndi ME / CFS akugona, iwo samadzuka kukhala omasuka ndi okonzekera tsikulo.
Ochita kafukufuku akudziŵa zambiri za kugona kosabwerera kwa ME / CFS, kuphatikizapo matupi ake, zotsatira zake, ndi momwe angachiritsidwe.
Kodi Kusagona Kosangalatsa N'kutani?
Kugona kosasangalatsa si chinthu chofanana ndi kusowa tulo (komwe kungakhaleko kwa anthu omwe ali ndi vutoli.) Sikuti mumakhala nthawi yaitali bwanji pamene mukugona kapena zovuta kufika kumeneko.
M'malo mwake, mawu ogona osasangalatsa amagwiritsidwa ntchito pofotokoza kugona tulo komwe ngakhale ngakhale usiku wonse usakupumulitseni. Anthu omwe ali ndi ME / CFS nthawi zambiri amafotokoza kuti akudzuka atatopa ndikumverera ngati kuti sanagone konse-ziribe kanthu kuti atagona nthawi yayitali bwanji. Zotsatira za kugona kosasangalatsa sizongotopa chabe.
Kugona kosasangalatsa kumayesedwa chifukwa cha vuto limene thupi lanu limayendetsa kugona, lomwe limatchedwa sleepostostasis. Ngakhale kuti anthu omwe ali ndi ME / CFS angakhale ndi mavuto okhudza kugona, maphunziro ambiri amapereka chiphunzitso chakuti nthawi zonse, kutopa kwawo kwakukulu kumachokera ku vuto losagona sleepostostisis osati ku matenda ena ogona. Ndipotu, phunziro la 2013 lomwe lafalitsidwa mu Sleep Medicine Reviews silinapangitse umboni kuti kuthana ndi matenda okhutira okhutira amathetsa kutopa kwa chikhalidwe ichi.
Zotsatira
Zizindikiro zambiri za ME / CFS zimapangidwira kuti mwina zimachokera m'tulo losabwerera. Zikuphatikizapo:
- kutopa kosalekeza
- kugona kwa masana
- kusamalidwa bwino ndi vuto lina lalingaliro ( ubongo wa ubongo )
- kuwonjezeka kwa kumva ululu ( hyperalgesia )
- kulemala kwakukulu
Nchifukwa chiyani kugona sikukuthandizani mu ME / CFS?
Kafukufuku wambiri wanena kusiyana kwakukulu kwa momwe anthu okhala ndi ME / CFS agona, kuphatikizapo:
- ubongo wa ubongo wambiri m'magulu angapo ogona
- kuchepa kwa nthawi yaitali
- nthawi yambiri akugona pa kama
- kugona kwa REM pang'ono ndi zina zosiyana-siyana za REM
- Kutsika kwapakati pamtima pamasinthasintha, kumatanthawuza kuti zovuta zimakhala zosavomerezeka
Kafukufuku wochulukirapo akugwirizanitsa chidziwitso cha kuwonongeka kwazidziwikiratu mu ME / CFS, yomwe ili vuto ndi dongosolo lokhazikika la mantha (ANS). ANS imapangidwa ndi machitidwe amanjenje aumphawi ndi aumphawi, omwe amagwira ntchito mofanana.
Pamene mchitidwe wamanjenje wachifundo umatsegulidwa, zimakupangitsani kumenyana-kapena-kuthawa. Mosiyana ndi zimenezi, kutsegula mwachisawawa kumatchulidwa ngati kupumula ndi kupopera.
Ngati wachifundo ndi wokhumudwa ali osayenerera chifukwa cholephera kugwira ntchito, zingakulowetseni kuti mukhale ndi chidziwitso pamene mukuyesera kugona. Zimakhala ngati momwe kholo latsopano limayang'anitsitsa mwana wodandaula, sakhala ndikugona bwino, tulo tofa nato.
Chithandizo
Ochita kafukufuku sanapange njira yowonjezera kuti athe kupeza njira zowonetsera kuti athetse tulo, choncho kuchepetsa kutopa ndi zizindikiro zina, mu ME / CFS. Pakadali pano, palibe mankhwala omwe ali a FDA omwe amavomereza matendawa.
Kafukufuku wa 2010 mu Zowawa Zochita zinasonyeza zotsatira zabwino ndi mankhwala osokoneza bongo Xyrem (sodium oxbate) .
Komabe, mankhwalawa amawongolera mwamphamvu ndipo nthawi zambiri zimakhala zovuta kupeza mankhwala.
Zofukufuku zowonjezera zowonjezera kugona za melatonin zasakanizidwa, ndipo kafukufuku wa 2010 mu Current Medicinal Chemistry akuti ntchito yambiri ikufunika kuti adziwe ngati ili yothandiza.
Anthu ena omwe ali ndi vutoli amafotokoza kuti amapambana ndi mankhwala omwe amawathandiza kuti agone, kuphatikizapo odwala matenda opatsirana pogonana komanso mankhwala othandiza anthu ogona. Ena amati mankhwala owonjezera amatithandiza kuti agone bwino. Mwamwayi, tili ndi kafukufuku wamtengo wapatali wosonyeza kuti mankhwalawa amachititsa kuti atha kugona mofulumira mu ME / CFS.
Mayi / CFS amakhulupirira kuti ndi ofanana ndi fibromyalgia , yomwe imakhalanso ndi tulo losasangalatsa. Mankhwala atatu ovomerezedwa ndi FDA a fibromyalgia onse asonyezedwa kuti apangitse tulo tomwe tili nawo. Iwo ndi Lyrica (pregabalin) , Cymbalta (duloxetine) ndi Savella (milnacipran) . Pakadali pano, palibe mankhwala awa omwe adawerengedwa kwa ME / CFS.
Madokotala nthawi zambiri amalimbikitsa njira monga kuphunzira njira zotsitsimutsira, kuwongolera makhalidwe ogona ndi kupeza chithandizo cha mavuto alionse ogona omwe mungakhale nawo.
Ngati ME / CFS yanu imapweteka, kupweteka koyenera kumathandizanso kuti mukhale ndi ubwino wogona.
Pogwira ntchito mwakhama ndi dokotala ndikuyesa njira zochiritsira zosiyanasiyana, mukhoza kupeza mankhwala omwe amathandiza kuchepetsa kugona osabwerera kuti muthe kusintha thanzi lanu, ntchito, ndi umoyo wanu.
Zotsatira:
> Mariman A, et al. Acta > clinica > Belgica. 2012 Jan-Feb; 67 (1): 19-24. Kukhala ndi ubwino wokhala ndi kugona komanso usana wa mchana ndi chitsanzo chachikulu cha odwala omwe ali ndi matenda aakulu (CFS).
Mariman AN, et al. Kuwerengera za mankhwala ogona. 2013 Jun; 17 (3): 193-9. Gonani mu matenda osatopa.
Mikirova N, Casciari J, Hunninghake R. Njira zochiritsira zowonjezera zathanzi ndi zamankhwala. 2012 Jan-Feb; 18 (1): 36-40. Kuwunika kwa mphamvu ya mphamvu yamagetsi ku odwala omwe ali ndi matenda otopa aakulu ndi seramu fluorescence emission.
Sanchez-Barcelo EJ, et al. Pakalipano mankhwala othandizira. 2010; 17 (19): 2070-95. Kugwiritsa ntchito mankhwala a melatonin: kuyesa kwa mayesero aumunthu.
Spitzer AR, Broadman M. Pain practice: magazini yovomerezeka ya World Institute of Pain. 2010 Jan-Feb; 10 (1): 54-9. Kuchiza kwa matenda a sleeping narcoleptiform mu matenda aakulu otopa ndi fibromyalgia ndi sodium oxbate.