Matenda a Kennedy

Zizindikiro ndi Chithandizo cha SBMA

Matenda a Kennedy, omwe amadziwikanso kuti spinal bulbar muscular atrophy kapena SBMA, ndi matenda okhudza ubongo. Matenda a Kennedy amakhudza maselo apadera a mitsempha omwe amachititsa kuti minofu iziyenda (makamaka magalimoto otsika apansi), omwe amachititsa kuyenda kwa minofu ndi miyendo. Zimakhudzanso mitsempha yomwe imayambitsa minofu ya bulbar, yomwe imalamulira kupuma, kumeza, ndi kuyankhula.

Matenda a Kennedy angapangitsenso kuti asrogen (mahomoni amphongo) asatengeke chifukwa amachititsa kuti mawere awonjezeke kwambiri, kuchepa kwachonde, ndi kupweteka kwa testicular.

Matenda a Kennedy amayamba chifukwa cha chibadwa cha chibadwa cha chromosome X. Popeza amuna ali ndi X chromosome imodzi yokha, amavutika kwambiri ndi matendawa. Amuna, omwe ali ndi ma X chromosome, akhoza kunyamula jini lopanda chilema pamtundu wina wa X chromosome, koma kachilombo ka X kamene kamachepetsa kapena kubisa zizindikiro za matendawa. Matenda a Kennedy akupezeka kuti alipo 1 mwa anthu 40,000 padziko lonse lapansi.

Zizindikiro za Matenda a Kennedy

Kawirikawiri, zizindikiro zimayamba mwa anthu omwe ali ndi zaka 40 mpaka 60. Zizindikiro zimadza pang'onopang'ono, ndipo zingaphatikizepo izi:

• Kufooka ndi kupweteka kwa minofu mu mikono ndi miyendo
• Zofooka za misomali, nkhope, ndi lilime. Chinsalu chikhoza kugwedezeka kapena kugwedezeka, ndipo liwu likhoza kukhala lamphuno kwambiri.
• Kuwombera minofu yaing'ono yomwe imawoneka pansi pa khungu.

• Mitambo kapena kunjenjemera ndi malo ena. Manja akhoza kunjenjemera pamene akuyesera kutenga kapena kugwira chinachake.
• Kuwongolera kapena kutayika kwa ziwalo zina za thupi.

Matenda a Kennedy akhoza kukhala ndi zotsatira zina pa thupi, kuphatikizapo:

• Gynecomastia , kutanthauza kutambasula kwa minofu ya m'mawere mwa amuna
• Testicular Atrophy, kumene ziwalo zoberekera zimachepetsa kukula ndi kutaya ntchito.

Kuzindikira kwa Chikhalidwe

Pali matenda ambiri a neuromuscular omwe ali ndi zizindikiro zofanana ndi matenda a Kennedy, kotero kuti matenda osadziwika bwino kapena osadziŵika bwino angakhale ofala.

Kawirikawiri, anthu omwe ali ndi matenda a Kennedy amaganiza kuti ali ndi amyotrophic lateral sclerosis (ALS, kapena matenda a Lou Gehrig). Komabe, ALS, komanso mavuto ena ofanana, sichiphatikizapo matenda a endocrine kapena kutaya kwa chisokonezo.

Kuyeza kwa chibadwa kungatsimikizire ngati kachilombo ka Kennedy kamakhalapo pa X chromosome. Ngati kuyezetsa kwa ma geneeni kulibwino, palibe mayesero ena omwe angafunikire kuchitidwa ngati matenda opatsirana angapangidwe kuchokera ku mayeso a chibadwa okha.

Kuchiza kwa SBMA

Matenda a Kennedy kapena SBMA samakhudza nthawi ya moyo, kotero kuti mankhwala akuwongolera kuti thupi likhale labwino kwambiri m'moyo wake kudzera mwa njira zotsatirazi:

• Kuchiza thupi
• Thandizo la ntchito
• Thandizo la kulankhula

Mankhwalawa ndi ofunika kuti akhale ndi luso la munthu komanso kuti asinthe matendawa. Zida zowonongeka monga kugwiritsa ntchito mipando kapena magalimoto olumala angathandize kukhalabe ndi ufulu komanso ufulu.

Uphungu Wachibadwa

Matenda a Kennedy amagwirizanitsidwa ndi chromosome ya X (yaikazi), choncho ngati mkazi ali ndi chithandizo cha jini lopanda chilema, ana ake amatha kukhala ndi mwayi wokhala ndi chithandizo cha 50% chokhala ndi chithandizo.

Abambo sangathe kudutsa matenda a Kennedy kwa ana awo. Komabe, ana awo aakazi adzakhala ogwira ntchito ya jini yolakwika.

_Zotsatira:

_{Barkhaus, PE (2003). Matenda a Kennedy.}

_{Gulu la Matenda a Kennedy. "Kodi Matenda a Kennedy Ndi Otani?"}