TSH Ndiyeso Yofunika Kwambiri Kuzindikira ndi Kuwunika Ntchito ya Chithokomiro
Kutanthauzira ma TSH sikuti ndiwongolingalira, kotero simuli nokha ngati mukudabwa kuti masewero anu a chithokomiro amatanthawuza chiyani , ndipo makamaka momwe mazinga a TSH otsika ndi otsika amatanthauza chithandizo.
Mwachitsanzo, mukhoza kukayikira chifukwa chake dokotala akufuna kuchepetsa mmalo mwakulitsa mankhwala anu a chithokomiro pamene zotsatira za TSH zanu ziri zochepa, kapena, chifukwa chake dokotala wanu akuwonjezera mankhwala anu a chithokomiro pamene TSH yanu ili pamwamba.
Dziwani kuti, ngakhale kuti zikhoza kuwonekera kumbuyo, zonsezi ndi zomveka pamene muyang'ana zamoyo za kutulutsa ma hormoni.
Matenda a Chithokomiro
Thanzi lanu la chithokomiro limapanga mahomoni a chithokomiro. Mukamagwira bwino ntchito yanu, chithokomiro chanu ndi mbali ya ndondomeko yanu yokhudzana ndi vuto lanu lomwe limaphatikizapo njira zingapo zofunika:
- Choyamba, pituitary yanu imamva mphamvu ya mahomoni otulutsa kachilombo yomwe imamasulidwa m'magazi.
- Nchito yanu yosungira mankhwala imatulutsa hormone yamtundu wapadera: chithokomiro chomwe chimayambitsa hormone (TSH). Udindo wa TSH ndikutulutsa chithokomiro kutulutsa mahomoni ambiri a chithokomiro.
- Pamene chithokomiro chanu, chifukwa chake, matenda, nkhawa, opaleshoni, kapena kutsekeka, mwachitsanzo-sichikhoza kapena sichikhoza kutulutsa homoni yowonjezera, shuga yanu imatengera kuchepa kwa hormoni ndipo imayamba kugwira ntchito mwa kupanga zambiri TSH, zomwe zimachititsa kuti chithokomiro chanu chikhale ndi mahomoni ambiri a chithokomiro. Izi ndizochita khama kuti awononge mahomoni a chithokomiro ndikubwezeretsanso dongosololi.
- Ngati chithokomiro chanu sichikugwira ntchito kwambiri ndipo chimachititsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda, kapena kuti tizilombo toyambitsa matenda timene timakhala ndi mankhwala otentha kwambiri. Kugwera kwa TSH ndi kuyesa kubwereranso kutulutsa mahomoni a chithokomiro kuti akhale oyenera.
Kutanthauzira Ma Level TSH
Mukamvetsetsa zowonongeka izi, zimakhala zosavuta kumvetsa zomwe TSH yochepa ndi TSH yapamwamba imasonyeza ponena za ntchito yanu ya chithokomiro.
Popeza TSH imatulutsa mahomoni a chithokomiro ndikusunga dongosololi moyenerera:
- TSH yapamwamba imasonyeza kuti chithokomiro chanu chilibe mphamvu (hypothyroid) ndipo sichita ntchito yake yopanga hormone yokwanira ya chithokomiro. Matenda owonjezera a TSH akugwira ntchito yotithandiza kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda.
- TSH yochepa imasonyeza kuti chithokomiro chanu chimakhala chopitirira muyeso (hyperthyroid) ndikupanga mahomoni ambiri a chithokomiro. Chithokomirochi chimapondereza TSH kotero kuti chithokomiro sichimawombera.
Kodi TSH ndi Yodalirika?
Pambuyo pa matenda, madokotala ambiri amagwiritsa ntchito mayeso a TSH kuti aone momwe chithokomiro chikuyendera ndikupeza njira yabwino yothetsera.
Komabe, onani kuti akatswiri ena amakhulupirira kuti kudalira TSH okha, popanda kuwonanso kuchuluka kwa mahomoni a chithokomiro, monga free thyroxine (T4), sangathe kuzindikira mavuto ovuta kwambiri a chithokomiro.
Mwachitsanzo, T4 yaulere kuwonjezera pa TSH imayesedwa kachiwiri ngati dokotala akuganiza kuti matenda a chithokomiro amatayika chifukwa cha matenda a chifuwa kapena hypothalamus. Chimodzimodzinso, ngati TSH ndi yachibadwa, koma munthu akadali ndi zizindikiro za hyperthyroid kapena hypothyroid, T4 yaulere ikhoza kuyang'anitsitsa.
TSH siyeneranso kuyang'anira hypothyroidism panthawi yomwe ali ndi mimba , ndichifukwa chake T4 ndi / kapena chiwerengero cha T4 chimayang'ananso.
Malingana ndi matenda a chithokomiro, mayesero ena a chithokomiro omwe angayesedwe amapezeka ndi triiodothyronine (T3), kachiwiri T3 , ndi mayesero a antibody.
Mapulogalamu a TSH
Chigwirizano chachikulu chomwe chikugwirizana ndi TSH ndi hypothyroidism ndi hyperthyroidism ndi kusagwirizana kosatha m'dziko lachipatala chifukwa cha zolembera za TSH.
Mipata yomwe ili pansipa 0.4 imalingaliridwa ngati umboni wotheka wa hyperthyroidism, ndipo mipando yapamwamba 5.0 imakhala yowoneka ngati umboni wodabwitsa wa hypothyroidism, koma akatswiri ena amamva kuti njirayi ndi yaikulu kwambiri ndipo iyenera kuchepetsedwa mpaka 0,4 mpaka 2.5mU / L.
Kusankha Mankhwala Ochokera ku TSH
Pamene mukuchiritsidwa ndi hypothyroidism ndi mankhwala a chithokomiro, mankhwala ambiri amachitiranso mankhwala omwe amapezeka mu TSH kuchokera ku 0.3 / 0.5 pamapeto, mpaka 3.0 / 5.0 pamapeto.
Choncho, mukapita kukafufuza ndipo TSH yanu imalowa pansi pafupipafupi (zomwe zikutanthauza kuti TSH ikuponderezedwa chifukwa mahomoni a chithokomiro ali kale pamwamba), dokotala wanu angafune kuchepetsa mlingo wanu wa hormone ya chithokomiro chifukwa muli kale hyperthyroid . Izi ndi chifukwa chakuti kuchotsa kwambiri TSH (kutanthauza kutentha kwa ma hormoni) kungapangitse munthu kutenga chiopsezo cha khansa (mtima arrhythmia) kapena osteoporosis.
Ndipo ngati chiyeso chanu cha TSH chimafika mwachibadwa, madokotala ena amafuna kuwonjezera mlingo wanu wa hormone ya chithokomiro, chifukwa miyezo yowonjezera imakhala ngati yotchedwa hypothyroid (yosagwira ntchito).
Mawu Ochokera
Mwachidule, mayeso a TSH ndi madokotala oyesera magazi omwe amagwiritsira ntchito poyesa kugwiritsira ntchito hypothyroidism ndi hyperthyroidism ndikuyang'ana mahomoni otengerako mankhwala (ngati akufunikira).
Ngakhale kuti zochitika zachipatala, monga kutenga mimba kapena kupita kuchipatala, zingafunike kuti T4 ndi T3 ziyezedwe, kumvetsetsa mfundo zazikulu za ma tshoni apamwamba kapena otsika amatanthauzanso kuti chithokomiro chanu ndi nyama ya zomwe muyenera kuzidziwa.
Izi zati, ngati muli ndi mafunso okhudza ntchito yokhudza magazi ya chithokomiro, onetsetsani kuti mufunse dokotala wanu.
> Zotsatira:
> Bahn, R., Burch, H, Cooper, D, et al. Hyperthyroidism ndi Zina Zimayambitsa Thyrotoxicosis: Malangizo Otsogolera a American Thyroid Association ndi American Association of Clinical Endocrinologists. Chitetezo cha Endocrine. Vol 17 No. 3 May / June 2011.
> Braverman, L, Cooper D. Werner & Ingbar's The Thyroid, 10th Edition. WLL / Wolters Kluwer; 2012.
> Garber, J, Cobin, R, Gharib, H, et. al. Malangizo Okhudza Zipatala za Hypothyroidism M'zochitika Zakale: Ambiri amathandizidwa ndi American Association of Clinical Endocrinologists ndi American Thyroid Association. " Chitetezo cha Endocrine. Mph. 18 No. 6 Novemba / December 2012.
> Ross DS. (2017). Kuyezetsa machitidwe a chithokomiro kumagwira ntchito. Mu: UpToDate, Cooper DS (Ed), UpToDate, Waltham, MA.