T4 / T3 Kuthana ndi Mankhwala a Chithokomiro

Mankhwala ovomerezeka, omwe amavomereza chithandizo cha hypothyroidism ndi mavitamini a chithokomiro omwe amachititsa mtundu wa mahomoni otchedwa thyroxine (T4). Izi zotchedwa Thyroxine zimadziwika kuti levothyroxine (ndipo nthawi zina l-thyroxine, kapena L-T4). Zina mwazinthu zomwe zimadziwika ndi Synthroid, Levoxyl, Tirosint , ndi Unithroid. Izi nthawi zambiri zimatchedwa "T4 mankhwala."

Komabe pali umboni wochuluka wosonyeza kuti odwala chithokomiro sagwiritsa ntchito mankhwala a T4 okha, ndipo amachita bwino powonjezera kuwonjezeka kwa mahomoni otchedwa thyroid, triiodothyronine (T3). Maonekedwe a T3 amadziwika ngati liothyronine, ndipo dzina lachidziwitso ku US ndi Cytomel. Izi zimatchedwa "T3 mankhwala."

Maonekedwe a chilengedwe, otengedwa ndi zinyama zonse za T4 ndi T3 amapezekanso m'zilembo zowonongeka Zachilengedwe Zotentha za Chithokomiro (NDT), zopangidwa ndi tizilombo toyambitsa matenda a chithokomiro. Mayina omwe amagwiritsidwa ntchito pamwambowu amachititsa kuti tizilombo toyambitsa matenda, WP Chithokomiro, ndi Chithokomiro cha Zida. Ku US, ma generic amadziwika kuti NP Chithokomiro.

Monga taonera, muyezo, mankhwala ochiritsira a hypothyroidism ndi mankhwala a levothyroxine okha. Kuwonjezera kwa T3 ku levothyroxine / T4-mankhwala okha - kapena kugwiritsa ntchito mankhwala opatsirana pogonana - ndizokangana ndi nkhani yopitiliza kufufuza ndi kukambirana. Kutsutsana kwa mankhwalawa kumafufuzidwa mwatsatanetsatane m'nkhani zazikulu zotsatirazi apa.

Mankhwala a T3 Amalimbikitsa Ubwino wa Moyo

Kafukufuku wowonjezera wa 1999 omwe analembedwa mu New England Journal of Medicine anapeza kuti umoyo wa anthu ochiritsidwa ndi hypothyroidism unasintha kwambiri ndi kuwonjezera mankhwala a T3 ku mankhwala awo okha a levothyroxine.

Ofufuzawo anapeza kuti "mankhwala opangidwa ndi thyroxine kuphatikizapo triiodothyronine amathandiza kwambiri odwala ambiri kuti akhale ndi moyo wabwino."

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2003 JAMA Phunziro limati T3 sizipindula

Magazini ya Journal of the American Medical Association (JAMA) inanena mu 2003 pa phunziro lovuta lomwe silinapeze phindu kwa odwala pamene T3 inawonjezeredwa ku mankhwala a T4 okha.

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Dr. Ken Blanchard pa Nkhani ya T4 / T3

Kumapeto kwa Dr. Ken Blanchard, MD, PhD, wolemba buku lakuti What Your Doctor May Not Tell You About Hypothyroidism, adatsutsa maphunziro a JAMA 2003.

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T4 / T3 Chithandizo Chofunika Odwala Phunziro

Magazini ya May 2005 ya Journal of Clinical Endocrinology ndi Metabolism inanena za kafukufuku amene adawonetsa kuti anthu omwe ali ndi hypothyroidism amakonda kusakaniza T4 / T3 mankhwala kuchipatala cha T4 okha. Ofufuzawo anapeza kuti mankhwala ophatikizana amaphatikizapo kulemera, pamene matenda a T4-okha sali.

"Odwala amasankha mankhwala okhudzana ndi matenda a LT4 / LT3 ndi mankhwala ochiritsira a LT4 ... Kuchepetsa kulemera kwa thupi kunagwirizanitsidwa ndi kukhutira ndi mankhwala ophunzirira ... zotsatira za phunziroli sizimapangitsa kuti gulu linalake la odwala lipindule ndi LT4 yothandizira / Mankhwala a LT3. "

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Zochitika Zachilengedwe Zomwe Mankhwala a Chithokomiro Amati Ndi Otetezeka

Kafukufuku wa 2003 wopangidwa ndi boma la US, akuyesa odwala hypothyroid ku Walter Reed Medical Center, adanena kuti mankhwala osokoneza bongo (NDT) omwe anali athanzi anali njira yabwino yothetsera levothyroxine okha.

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Phunziro lachi Denmark likuwonjezera T3 Wopambana ndi T4-Yekha

Kafukufuku wamkulu adafotokozedwa mu European Journal of Endocrinology , akuyang'ana pazovuta za mankhwala omwe ali ndi t3 yokhazikika monga tizilombo toyambitsa matenda a T4-yekha (levothyroxine) kwa hypothyroidism.Thefukufukuwo adapeza kuti kuphatikiza T4 / T3 kuliposa T4 mankhwala okhaokha / levothyroxine a hypothyroidism.

Kupeza kofunika:

Onse okwana 49% adakonda kusakanikirana, ndipo 15% okha amangofuna mankhwala a levothyroxine okha.

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Kodi Mukufunikira T3 Kuti Muzimva Bwino?

Odwala ambiri a chithokomiro atitumizire pano komanso pa tsamba la Thandizo la Facebook, ndipo funsani funso lomwelo: "Ndili pa Synthroid (kapena mankhwala ena a levothyroxine monga Levoxyl) ndipo sindikumva bwino. " Kodi odwala chithokomiro amafunika kudziwa ndi chiyani, ndi izi: Kodi mungapindule ndi kuwonjezera kwa T3 yowonjezera?

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Kodi Mukufunikira T3 Kapena Chithokomiro Chodabwitsa?

Ngati muli ndi mankhwala osokoneza mavitamini otchedwa hormone (ie, generic levothyroxine, kapena Synthroid, Levoxyl, kapena Tirosint). Ndipo simukumva bwino, mwina mungapindule ndi kuwonjezera T3, kapena kusintha mankhwala a chithokomiro omwe akuphatikizapo T3 .

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Kafukufuku Watsopano

Mfundo imodzi yodalirika pa mkangano pa T4-yokha pokhapokha ndi T3 / T3 mankhwala othandizira kuti hypothyroidism ndi phunziro lalikulu lofufuza lomwe likukonzekera mu 2018. Phunziroli lidzawoneka pa magawo osiyanasiyana, kuphatikizapo umoyo wa moyo ndi kukhutira kwachisangalalo, pamodzi ndi nthawi zonse Ndondomeko ya kuyezetsa magazi, kuyerekeza levothyroxine motsutsana ndi levothyroxine pamodzi ndi T3, komanso kuyerekezera mankhwala awiriwa motsutsana ndi chithandizo cha chithokomiro chachibadwa. Phunziroli liwonanso kufalikira kwa mitundu yosiyanasiyana, yomwe imatchedwa polymorphism, yomwe ingapangitse T3 kukhala yothandiza kwambiri kapena oyenerera kwa odwala ena a hypothyroid. Maphunzirowa, omwe amapangidwa mobwerezabwereza, omwe amawunikira anzawo, omwe amapangidwa ndi omwe amatsogoleredwa ndi atsogoleri ena omwe amatsogoleredwa ndi zipatala, ndipo amapitsidwira kudzera m'mabungwe akuluakulu azachipatala ndi zipatala, osadulidwa ndi makampani aliwonse ogulitsa mankhwala. Zotsatirazo zikatulutsidwa, phunziroli likhoza kusintha kwambiri malangizo a mankhwala a hypothyroidism, poonetsa kuti mankhwala a levothyroxine / T4, T4 / T3, ndi mankhwala a NDT ndi otetezeka komanso ogwira ntchito. Phunziroli lingasonyezenso kuti Kuwonjezeka kwa T3 kumapangitsa kuti moyo wabwino ukhale wabwino kwa ena kapena ngakhale ambiri mwa odwala hypothyroid. Phunziroli liyeneranso kusonyeza ngati ma poymomphism a ma genetiki akugwirizana ndi kufunikira kwa T3 monga gawo la mankhwalawa. Khalani maso kuti mudziwe zambiri!