Carcinoembryonic Antigen (CEA) Yodziwika Kugwiritsa Ntchito Magazi

Kuphunzira Zambiri Zokhudzana ndi Kudziletsa

Imodzi mwa njira zosavuta kuti muwone khansa zina ndi kupyolera mwa njira yosavuta ya magazi yomwe imatchedwa kuyesa chizindikiro cha chotupa. Kukhalapo kwa khansa zina kumatsimikiziridwa ndi mapuloteni enieni omwe amakhetsedwa m'magazi. Mapuloteni amenewa ndi zotupa . Carcinoembryonic antigen (CEA) ndi mapuloteni okhudzana ndi khansa yambiri .

Aliyense wa ife ali ndi CEA pang'ono m'magazi athu.

Kukhalapo kwa mapuloteniwa mu magazi okha sikukutanthauza kuti muli ndi khansara yamtunda. Mayeso a magazi a CEA sangagwiritsidwe ntchito kuti azindikire khansa , koma kuti ayang'ane khansa pambuyo pozindikira kuti ali ndi khansa . Dokotala wanu mwinamwake anafufuza magazi anu kwa antigen uyu pamene inu mwapezeka. Ngati kuchuluka kwa CEA kunapezeka m'magazi anu panthawiyo, dokotala wanu angagwiritse ntchito kuti ayang'ane mayankho anu kuchipatala ndikuyang'ananso kuyambiranso kuyesa magazi.

Zotsatira zabodza zabodza - zotsatira zomwe ziri zazikulu koma sizikusonyeza kukula kwa khansa - zikhoza kuchitika ndi CEA. Chimodzi mwa zifukwa zazikulu zowerengera mosamveka ndi mankhwala a chemotherapy . Pa mankhwala a chemotherapy, mankhwalawa amafunika kuwombera ndi kupha maselo a kansa . Pamene maselowa amwalira, CEA imamasulidwa m'magazi ndipo ikhoza kukhala yowonjezera kwa masabata angapo pambuyo pa chithandizo.

Mitundu Yambiri ya Matenda a Tumor

Maseŵera a CEA akhoza kukwezedwa ndikutanthauza kubwereza kwa khansa kapena kufalitsa ( metastasis ) ku malo ena m'thupi lanu.

Maseŵerawa amawoneka okwera poyerekeza ndi nanograms 3 pa mililita (ng / ml) ndipo ali okwera kwambiri pamene ali pamwamba pa 5 ng / ml. Kuwonjezera pa kuwonetsa kukula kapena kukana khansa yodabwitsa , mkulu wa CEA angathenso kugwiritsidwa ntchito kuyang'ana khansara kapena metastasis ya:

• Chiwindi
• Mimba
• Chithokomiro
• Pancreas

• Prostate
• Chotsitsa
• Chikhodzodzo

Komabe, ena mwa khansawa ali ndi zizindikiro zambiri zokhudzana ndi zotupa zomwe zikugwirizana nawo. Mwachitsanzo, chizindikiro cha alpha-fetoprotein (AFP) chikugwirizana ndi khansa ya chiwindi ndipo chizindikiro cha prostate-specific antigen (PSA) chimadziwika kwambiri ndi khansa ya prostate . Dokotala wanu sagwiritsira ntchito choyimitsa chotupa yekha - iye adzaphatikiza zotsatira zanu za magazi ndi zida zina zothandizira, monga thanzi lanu lonse, mayendedwe ochiritsira, ndi mayesero ojambula, monga kuwerengedwa kwa computed tomography (CT) kapena maginito zojambula za resonance (MRI) zotsatira.

Chinthu china chomwe chimatchedwa epidermal growth factor receptor (EGFR), chiri mu selo iliyonse ndikuwathandiza kukula. Ena khansa amasonyeza bwino kwambiri EGFR , zomwe zikutanthauza kuti akhoza kukhala ndi njira zosiyana zothandizira.

Mwinamwake mwamvapo za chinachake chomwe chimatchedwa biomarker kwa matumbo a khansa ya coloni. Chinthu chimodzi chodziwika bwino chomwe chimapezeka ndi mtundu wa KRAS; Malingana ndi National Comprehensive Cancer Network, anthu 40% omwe ali ndi khansa ya coloni adzakhala ndi KRAS gene mutation. Dokotala akhoza kuyesa minofu ku chotupa chanu cha colon chifukwa cha kusintha kumeneku, komwe kungathandize dokotala kupanga ndondomeko yanu ya mankhwala ku khansa yanu ya mtundu wa khansa .

CA 19-9 inadziwika ngati chotupa chokhala ndi khansa yapaderayi m'mbuyomo koma tsopano ndi yofunika kwambiri kwa khansa yapakhungu ndi zina zotero. Komabe, dokotala wanu angasankhe kuti ayese magazi anu pa makanema akulu a CA 19-9 pamodzi ndi kuyesedwa kwa CEA.

Kupeza Mayeso

Simusowa kukonzekera kapena kusala kudya musanayese magazi awa. Pa tsiku la kuyesedwa kwanu, nyemba yaing'ono yamagazi idzachotsedwa ku chimodzi mwa mitsempha yayikuru mu mkono kapena dzanja lanu. Ngati n'kotheka, ndibwino kukhala ndi labotala yomweyi kuti muyese ma testato anu a CEA, chifukwa momwe muyeso ndi zipangizo zingagwiritsire ntchito labu ndi labata. Dokotala wanu atalandira zotsatira za CEA, akhoza kukambirana ndi inu ndikufotokozera momwe angathere (kapena ayi) kusintha mapulani anu.

Kupatula khansara, zolemba zotupa zimatha kukwera pa zifukwa zingapo. American Cancer Society imanena kuti anthu omwe amasuta kapena odwala matenda opatsirana pogonana , matenda osokoneza bongo (COPD) kapena ngakhale chiwindi cha hepatitis akhoza kukhala ndi mikhalidwe yapamwamba ya CEA popanda kukhala ndi khansa.

Mayesero Otsatira

Mutha kukhala ndi mayesero okhudzana ndi zotupa, makamaka ngati mwakweza pamwamba pa ma ARV ngati mutapezeka ndi khansa. Ngati mgwirizano wa CEA ukasiya zotsatira za opaleshoni yamakono kapena opaleshoni ya m'mimba , ndiye kuti udzathamangidwanso m'tsogolomu, zikhoza kukhala chisonyezero chakuti khansa inabwereranso. Zotsatira za zotsatira za mayesero ndizowonetseratu kuposa zotsatira imodzi.

_Zotsatira:

_{American Cancer Society. (2006). Buku Lopatulika la American Cancer Society Loyamba kwa Khansa Yoyamba . Clifton Fields, NE: American Cancer Society.}

_{American Cancer Society. (nd). Kodi Timor Markers Zimagwiritsidwa Ntchito Bwanji?}

_{Lano, Charlene. (November 2009). Odwala EGFR & Calarectal Cancer: Kuyeza KRAS Kunatsimikiziridwa, Koma Mafunso Otsopano. Oncology Times, 31. doi: 10.1097 / 01.COT.0000364239.69157.69.}

_{National Cancer Institute. (nd). Zolemba Zosokoneza.}

_{National Comprehensive Cancer Network. (2012). Zotsatira za NCCN kwa Odwala. Khansara ya Colon.}