Ngati estrogen ndi mahomoni opatsirana pogonana pakati pa amai, ndiye kuti progesterone ndiwodalirika. Progesterone ili ndi ntchito zake zofunika kwambiri m'thupi lanu, koma imathandizanso kuti muyambe kugwiritsira ntchito estrogen, makamaka mu chiberekero cha chiberekero chanu.
Kupanga Progesterone: Ndi (pafupifupi) Zonse Zonse Zokhudza Ovary Yanu
Progesterone imapangidwa makamaka ndi gawo lina la ovari yomwe imatchedwa corpus luteum.
The corpus luteum imayamba kuchokera ku follicle yomwe imatulutsa dzira pa ovulation. Pambuyo pa kuvuta kwake, corpus luteum imayambitsa kupanga kwake kwa progesterone.
Progesterone ndi hormone yaikulu m'kati mwa magawo awiri kapena theka la kumwezi kwako, ndipo udindo wake ndi kupitiriza ntchito ya estrogen pokonzekera chiberekero cha chiberekero chanu cha mimba. Ngati dzira limene mumatulutsa limamera ndi umuna ndipo mukakhala ndi pakati, corpus luteum ikupitirizabe kubala progesterone mpaka masabata khumi a mimba. Ndiye, placenta yanu imatenga. Ngati simutenga mimba, ndiye kuti corpus luteum yanu imasungunuka, ma progesterone anu akugwa, mumatenga nthawi yanu, ndikuyamba kusamba.
Kuphatikiza pa corpus luteum ndi placenta, progesterone imapangidwanso koma kwa digiri yaing'ono ndi mazira ndi ma adrenal glands.
Progesterone Ndi Yofunika Kwambiri pa Umimba Wathanzi
Monga tafotokozera pamwambapa, udindo wa progesterone mu mimba imayamba ngakhale asanakhazikitsidwe dzira la umuna.
Progesterone ndi yofunika kwambiri kuti mupeze ndi kusunga mimba yabwino yomwe ili pafupi masabata khumi, placenta yanu imayambitsa kupanga progesterone kwa mimba yanu yotsalayo. Zimaganiziridwa kuti progesterone imakhala ndi zodana ndi zotupa zomwe zimakhudza thupi lanu. Ntchito izi za progesterone zimateteza kutenga mimba yoyamba kutuluka pakapita padera komanso kupewa kutaya mimba pambuyo pake.
Kwa amayi ena, zingakhale zofunikira kutenga progesterone yowonjezerapo panthawi yoyembekezera.
Ngati mwakhala ndi chithandizo chothandizira zipangizo zamakono zomwe simunapange mwachibadwa, simungakhale ndi mankhwala abwino kuti mukhale ndi progesterone. Dokotala wanu angakulangize mtundu wina wothandizira wa progesterone ngati mawonekedwe a gel kapena piritsi yamaliseche kapena ndi jekeseni ya m'mimba. Progesterone supplementation imeneyi imakhala ikupitirira mpaka milungu isanu ndi iwiri ya mimba.
Ngati muli ndi mbiri yowonongeka kale komanso / kapena kuti musanayambe kutaya mimba m'mimba yam'mbuyomu, mukhoza kukhala woyenera kugwiritsa ntchito progesterone kuti muteteze kubereka koyambirira. Awa ndi jakisoni sabata iliyonse ya mtundu wina wa progesterone umene umayamba pamasabata 16 ndikupitirira kwa masabata 36 a mimba.
Progesterone ndi Mabere Anu
Progesterone imathandiza kwambiri pakukula mawere. Kuyambira pa msinkhu, progesterone imalimbikitsa kukula kwa minofu ya m'mawere.
Panthawi iliyonse ya mankhwalawa, minofu imeneyi imalimbikitsidwa, koma mpaka mutatenga mimba kuti progesterone ikwaniritse ntchito yokonzekera mabere anu kupanga mkaka ndi lactation.
Kuwonjezereka kwa pulojekiti ya progesterone ndi ntchito zomwe zimachitika pa nthawi ya msambo zikuganiziridwa kuti ndizo zimayambitsa ubweya, kupweteka, ndi chifundo chimene nthawi zambiri zimapezeka pa nthawi yomwe amayamba msambo. Kupweteka kwa m'mawere kapena mastalgia ndi chizindikiro chofala cha PMS.
Progesterone & Progestin: Kodi Zili Zofanana Kapena Zosiyana?
Progesterone ndi hormone yachibadwa yomwe imapangidwa ndi thupi lanu, makamaka ndi corpus luteum. Chifukwa progesterone imachotsedwa mofulumira kuchokera m'thupi pamene imaperekedwa pamlomo zimakhala zovuta kugwiritsa ntchito progesterone ngati chowonjezera, makamaka ngati pakufunika kokha muyezo wochepa.
Progesterone imagwiritsidwa ntchito pazinthu zina monga kupewa ntchito yoyamba kapena kubereka mimba yoyamba pambuyo pa IVF, koma nthawi zambiri imaperekedwa mwakachetechete kapena kumaliseche kuti thupi lanu lizikonda. Nthaŵi zina progesterone yamagetsi imaperekedwa pamlomo ngati mbali ya mphamvu yowonongeka ya homopa.
Ambiri pofuna kuthana ndi vuto ndi kuyamwa, mtundu wa progesterone unalengedwa ichi ndi chimene chimatchedwa progesin. Pogwiritsa ntchito makina a progesterone ochiritsira omwe amachititsa kuti pakhale mavitamini a progesterone mumthupi mwathu. Mankhwala opatsirana amagwiritsidwa ntchito pa njira zonse zothandizira kulandira mahomoni monga:
- piritsi lachinsinsi
- kulandira mimba
- kulandira chithandizo
- zokhudzana ndi progestin zokhudzana ndi IUD
Ambiri mwa mankhwalawa amachokera ku testosterone, ndipo malingana ndi mtundu wa progestin akhoza kukhala ndi testosterone ngati ntchito. Mwachitsanzo, m'badwo wachitatu progestin udzakhala ndi lessrogenic kapena testosterone yochepa ngati chinthu choyambirira, kuti chikhale chabwino pa chisawawa koma choipa kwambiri pa galimoto yanu.
Udindo wa Progesterone Poteteza Endometrium Yanu
Zochita za Progesterone pazitsulo za chiberekero chanu ndi kumene zimagwira ntchito monga estrogen's sidekick. Mu njira yachibadwa yomwe imapangitsa kuti musatenge mimba, kumangirira ndi kukhetsa chiberekero cha chiberekero chanu kumayendetsedwa ndi mgwirizano pakati pa estrogen ndi progesterone. Ngati muli ndi vuto lomwe mulibe ovulating koma muli otero ambiri, zomwe ziri mu polycystic ovarian syndrome ndipo nthawi zina mukunenepa kwambiri, dokotala wanu angagwiritse ntchito kugwiritsa ntchito progestin kuti muteteze chikwama cha chiberekero chanu ndi kuchiza chinthu china chosazolowereka magazi otuluka m'mimba omwe angabwere.
Mankhwalawa amagwiritsidwanso ntchito m'malo ambiri omwe angasankhe kuti azisintha. Pamene mukuyamba kusamba, zizindikiro zambiri zosasangalatsa zimayamba chifukwa cha kusowa kwa estrogen. Kutenga mayendedwe a estrojeni yokha kudzateteza zizindikiro izi ndikuziteteza mafupa anu. Komabe, ngati muli ndi chiberekero chanu muyenera kugwiritsa ntchito progesin kapena progesterone kuti mupewe kukula kosawonongeka kwa endometrium yomwe ingathe kutsogolera khansa ya m'magazi.
Kusokonezeka kwa Progesterone ndi Luteal Phase Mood Disturbances
Mofanana ndi estrogen, progesterone imagwirizana ndi mankhwala mu ubongo wanu kuti muzitha kusintha maganizo anu komanso mmene mungakhalire bwino. Njira yomwe progesterone imachitira izi ndi kudzera mu metabolite, ndilo lotchedwa allopregnanolone. Allopregnanolone imagwira ntchito pamtundu wina mu ubongo wanu wotchedwa GABA receptor. Kawirikawiri zimakhala ndi nkhawa kwambiri komanso zimakhala zofanana ndi zomwe zimachitika mowa ndi mankhwala ena osokoneza bongo monga benzodiazepines. Ichi ndichifukwa chake mumatha kugona tulo kapena mphamvu zochepa panthawi yanu isanakwane kapena kumayambiriro kwa mimba.
Koma kwa amayi ena, kukula kwa puloteni kungapangitse nkhawa komanso kusokonezeka. Zotsatira zofananazi zikhoza kuchitika ndi zina zotchedwa progestins zomwe zimagwiritsidwa ntchito mu mankhwala opatsirana pogonana. Zimaganiziridwa kuti chosiyana ndi zomwe zimachititsa kuti progesterone iwonongeke zimayambitsa kusokonezeka kwa momwe akazi ovutawa amachitira ndondomeko ya allopregnanolone.
Mawu Ochokera
Progesterone, pamodzi ndi estrogen, ndizo zazikulu zogonana mu thupi la mkazi. Amagwirira ntchito pamodzi kukonzekera thupi lanu kuti mukhale ndi pakati ndi maulendo onse omwe amathandiza kuti thupi lanu likhale labwino. Ndikofunika kumvetsetsa kuti progesterone imawoneka bwanji m'thupi lanu komanso momwe ilili ndi zotsatira zabwino komanso zotsatira zake zoipa.
> Zotsatira:
> Backstrom T, Bixo M, Stromberg J. (2015). GABAA Receptor-Modulating Steroids mu Zokhudzana ndi Umoyo wa Akazi. Curr Psychiatry Rep.17 (11): 92 doi: 10.1007 / s11920-015-0627-4
> Kumar, P., & Magon, N. (2012). Mahomoni m'mimba. Nigerian Medical Journal: Journal of the Nigeria Medical Association , 53 (4), 179-183. http://doi.org/10.4103/0300-1652.107549
> Macias, H., & Hinck, L. (2012). Mammary Gland Development. Zowonongeka za Wiley. Biological Development , 1 (4), 533-557. http://doi.org/10.1002/wdev.35