Mmene Mungachiritse Gout ndi Zakudya ndi Mankhwala

Kodi Njira Yabwino Yothandizira Odwala?

Gout kawiri kaŵirikaŵiri amagwiritsa ntchito umodzi umodzi mwadzidzidzi komanso mwamphamvu. Kawirikawiri, yoyamba ya metatarsophalangeal ( chophimba chachikulu ) imakhudzidwa, koma ziwalo zina zingakhudzidwe. Mankhwala osakaniza amasonyeza zizindikiro zooneka za kutupa (mwachitsanzo, kufiira). Cholinga chachikulu cha chithandizo ndikuteteza kusokoneza komwe kulipo ndikupewa kuteteza matendawa.

Nazi momwe:

1. Kuyamba koyamba kwa gout kungakhale masiku angapo ndipo kumatayika ngakhalenso osatulutsidwa. Kugonjetsa kumeneku sikungakhoze kuchitika kwa masabata, miyezi, zaka, kapena ayi. Matenda oopsa a gout (mwachitsanzo, kuukiridwa mobwerezabwereza kumachitika kwa nthawi yayitali) kungayambitse ziwalo zomenyedwa ndi kutayika. Ndondomeko ya chithandizo ndi yofunikira kuti muteteze kuukiridwa ndi kuwonongeka pamodzi.

1. Gout amagwirizana ndi vuto lopanda kubadwa chifukwa chopanga uric asidi m'thupi. Mafuta a uric amatha kukhala okwera kwambiri chifukwa chodyera zakudya zopatsa mphamvu za purine , pamene pali uric acid wambiri mwa thupi, kapena impso sizichotsa oric acid.
2. Zolinga zamankhwala zimaphatikizapo kuthetsa masewera olimbitsa thupi , kupumula kwa ululu ndi kutupa, kuteteza masoka amtsogolo, ndi kupeŵa mavuto (mwachitsanzo, mapangidwe a tophi , miyala ya impso, ndi chiwonongeko chogwirizana).
3. Ngakhale mankhwala opatsirana amachiritsidwa kawiri kaŵirikaŵiri komanso popanda mavuto, zimakhala zovuta kwambiri ngati zinthu zina zilipo pamodzi ndi gout kapena ngati pali osauka kutsatira malamulo oyenera kusintha kapena mankhwala a regimen.
4. Kusintha kwa zakudya kumalimbikitsidwa, monga kupeŵa zakudya zopatsa purine . Njira zina zothandizira kumaphatikizapo kukhala ndi madzi okwanira, kuchepetsa kulemera, kuchepetsa kumwa mowa, komanso mankhwala ochepetsera magazi.

1. Mankhwala a gout ndi awa:
   • mankhwala osagwiritsa ntchito mankhwala ochepetsa kutupa (NSAIDS)
   • colchicine
   • corticosteroids
   • adrenocorticotropic hormone (ACTH)
   • allopurinol
   • probenecid
   • sulfinpyrazone
   • Uloric (febuxostat)
   • Krystexxa (pegloticase)
2. NSAIDS kawirikawiri imakhala mankhwala oyambirira omwe amafunika kuti azichiza gout. Indomethacin amaonedwa kuti ndi othandiza. NSAIDS ina ingakhale yogwira ntchito mofanana. NSAIDS poyamba imayesedwa pa mlingo woyenera kulandira ndi kuchepetsedwa ngati zizindikiro zikuchepa. Mankhwalawa ayenera kupitilizidwa mpaka kupweteka ndi kutupa siziripo kwa maola oposa 48. COX-2 inhibitors angakhale othandiza kwa odwala m'mimba mwawo koma ntchito yawo ya gout yovuta siinaphunzire mwachindunji kapena kunenedwa.

1. Colchicine amagwiritsidwa ntchito pochizira matenda oopsa a nyamakazi komanso kupewa kuthamangitsidwa koopsa. Colchicine samachiza gout kapena kutenga mankhwala ena omwe amachepetsa kuchuluka kwa uric acid mu thupi. Mankhwalawa amaletsa kapena amachepetsa masewera a gout pochepetsa kuchepa. Colchicine ingagwiritsidwe ntchito m'njira ziwiri: anthu ena amatenga pang'ono pang'onopang'ono kwa miyezi kapena zaka, pamene ena amatenga colchicine zambiri panthawi yochepa (maola angapo).
2. Corticosteroids kapena adrenocorticotropic hormone ingagwiritsidwe ntchito kwa odwala omwe sangathe kutenga NSAIDS kapena colchicine. Odwala omwe ali ndi gout wambiri amalandira mlingo wa tsiku ndi tsiku (20-40mg) kapena ofanana nawo masiku atatu kapena 4, ndiye amatha kupitirira pang'onopang'ono kwa masabata awiri kapena awiri. ACTH imayendetsedwa ngati jekeseni ya m'mimba (mlingo woyamba ndi mlingo wotsatira pambuyo pa masiku angapo ngati mukufunikira).
3. Allopurinol (dzina lake - Zyloprim) , limene limaperekedwa kuti likhale ndi matenda aakulu a amthempha, limagwira ntchito pogwiritsa ntchito njira yomwe imapanga uric acid m'thupi. Amagwiritsidwa ntchito popewera matenda a gout, osati kuwachitira kamodzi akangochitika.
4. Probenecid (maina a chizindikiro - Benemid, Probalan) amalembedwa kwa gout osasinthasintha komanso odwala matenda a nyamakazi. Zimagwiritsidwa ntchito popewera zida zokhudzana ndi msuzi, osati kuzisamalira kamodzi zikachitika. Amagwira impso kuti athandize thupi kuchotsa uric acid. Probenecid amadziwika kuti wricosuric agent.

1. ColBenemid (mayina ena amodzi ndi Col-Probenecid ndi Proben-C) ndi mankhwala a gout omwe ali ndi Probenecid, yemwe ndi wothandizira, komanso Colchicine, omwe ali ndi anti-gout.
2. Sulfinpyrazone (dzina lachidziwitso - Anturane) amadziwikanso ngati wothandizira mankhwala ndipo amagwiritsidwa ntchito pochiritsa matenda a nyamakazi. Zimagwira ntchito pochepetsa kuchuluka kwa uric acid m'magazi anu, kuteteza matenda a gout . Mankhwalawa amathandiza kupewa zowonongeka koma sagwiritsidwa ntchito pofuna kuchiza chiyambi pomwe chayamba. Sulfinpyrazone salipo tsopano ku US
3. Losartan, (dzina lachidziwitso - Cozaar ndi Hyzaar), sichidziwika bwino ndi mankhwala a gout koma ndi mankhwala a angiotensin omwe amalandira mankhwala osokoneza bongo omwe angathandize kuchepetsa ma oric acid. Fenofibrate, (dzina lachidziwitso - Tricor), si mankhwala enieni a gout koma ndi mankhwala ochepetsa mankhwala omwe angathandize minofu ya uric acid.

1. Mankhwala opweteka amathanso amagwiritsidwa ntchito kuthetsa ululu waukulu wa gout. Mankhwala onse omwe tatchulawa angagwiritsidwe ntchito pamodzi, kuteteza zizindikiro, kupewa masoka amtsogolo, ndi kusunga ma uric acid.
2. Krystexxa (pegloticase) ndi mankhwala osokoneza bongo . Zimagwira ntchito polepheretsa uric acid. Amagwiritsidwa ntchito pa odwala opatsirana omwe amalephera kapena sangathe kulekerera mankhwala ochiritsira a gout.
3. Uloric (febuxostat) ndi mankhwala omwe amagwiritsidwa ntchito kuti azisamalira bwino matenda a hyperuricemia mu gout . Uloric imachepetsanso mphamvu za serum uric acid poletsa xanthine oxidase - enzyme yomwe imayambitsa uric acid kupanga.

Malangizo:

1. Sungani chakudya chokwanira cha madzi.
2. Pitirizani kulemera kwanu. Kunenepa kwagwirizanitsidwa ndi gout.
3. Kusintha kwa zakudya kungathandize kupewa masewera a gout. Pewani zakudya zopatsa purine. Pewani kumwa mowa.
4. Mankhwala amathandiza kuchepetsa kupweteka komanso kutupa kwa gout komanso kuthandizira kupewa masewera olimbana ndi uric acid kapena kuwononga oric acid.
5. Khalani ovomerezana ndi dongosolo la mankhwala omwe dokotala wanu amalimbikitsa.

Zimene Mukufunikira:

• Kudya pansi mu purines.
• Mankhwala kuti athetse ululu.
• Mankhwala oletsa kutupa.
• Mankhwala amatha kuika mlingo wa uric acid.