Phunzirani zambiri za AMC, Wokhala Wokhulupirika Wosakaniza
Arthrogryposis kapena arthrogryposis multiplex congenita (AMC) ndi dzina loperekedwa ku matenda amodzi omwe amachitidwa ndi kukonza mgwirizano wochuluka mthupi lonse. Chigwirizano ndi chomwe chiwalo chimakhala cholimba ndipo chimakhala chokhazikika kapena chowongolera, zomwe zimapangitsa kuti zitsulo zisinthe.
Matendawa amayamba asanabadwe (ndi vuto lobadwa ) ndipo ku US, amapezeka kamodzi pa onse 3,000 kubadwa, zomwe zimakhudza amuna ndi akazi amitundu yonse.
Zambiri kuposa gawo limodzi la thupi ziyenera kuthandizidwa chifukwa cha matenda omwe amatchedwa arthrogryposis. Ngati mgwirizano wa mgwirizano umachitika pambali imodzi ya thupi (monga mapazi, chikhalidwe chotchedwa clubfoot ) ndiye kuti ndi mgwirizano wokhawokha wosagwirizana ndi arthrogryposis.
Pamene mbali ziwiri kapena zingapo zosiyana za thupi zimakhudzidwa ndi arthrogryposis, chikhalidwecho chikhoza kutchedwa arthrogryposis multiplex congenita (AMC) ndipo nthawizina mayina onsewa amagwiritsidwa ntchito mosiyana. Pali mitundu yoposa 150 ya AMC, ndipo amyoplasia ndi yofala kwambiri komanso imapereka ndalama zambiri pazinthu zoposa 40% za AMC.
Zomwe Zimayambitsa Arthrogryposis Multiplex Congenita (AMC)
Arthrogryposis kawirikawiri imayamba chifukwa cha kuchepa kwa fetus m'mimba. Mwana wakhanda amafunika kuyenda m'miyendo kuti apange minofu ndi ziwalo. Ngati manjenje samasunthira, minofu yowonjezera imayamba kuzungulira palimodzi ndikuikonza.
Zina mwa zifukwa za kuchepa kwa fetus ndi:
- Malingaliro kapena zovuta zapakatikatikati za mitsempha yambiri (chifukwa chofala), monga spina bifida , kupweteka kwa ubongo, kapena kupweteka kwa msana pamtumbo
- Matenda otchedwa neuromuscular disorder monga myotonic dystrophy, myasthenia gravis, kapena multiple sclerosis
- Matenda a amayi pa nthawi ya mimba monga chimanga cha German (rubella) kapena rubeola
- Matenda a amayi opitirira 39C (102.2F) kwa nthawi yayitali, kapena kutentha kwa thupi la amayi chifukwa cha kutayika kwa nthawi yaitali m'matentha otentha
- Kutengera kwa amayi ku zinthu zomwe zingayipitse mwana, monga mankhwala osokoneza bongo, mowa, kapena mankhwala osokoneza bongo otchedwa phenytoin (Dilantin)
- Mankhwala amniotic pang'ono, kapena kuthamanga kwa amniotic madzi, angapangitse malo ochepa kuti mwanayo asunthe
Zizindikiro za AMC
Ma mgwirizano omwe amapezeka m'mwana wakhanda ali ndi arthrogryposis amasiyanasiyana kuyambira mwana mpaka mwana, koma pali zizoloŵezi zofanana:
- Miyendo ndi manja zimakhudzidwa, ndi zikopa ndi mitsempha kukhala opunduka kwambiri (ganizirani za kamwana kamene kakapulidwa mkati mwa chiberekero, kenaka chatsekedwa mu malo amenewo)
- Mafundo m'milingo ndi manja sangathe kusuntha nkomwe
- Misendo miyendo ndi manja ndi ofooka ndi ofooka kapena ngakhale palibe
- Chiuno chikhoza kuchotsedwa
Ana ena omwe ali ndi arthrogryposis ali ndi zofooka za nkhope, kupindika kwa msana, kutaya kwa thupi, matenda a mtima ndi kupuma, ndi zofooka za khungu.
Kuchiza kwa Arthrogryposis Multiplex Congenita
Palibe mankhwala a arthrogryposis, ndipo chithandizochi chikuwonekera ku zizindikiro zomwe munthu angakhale nazo.
Mwachitsanzo, mankhwala oyambirira amphamvu kwambiri amathandizira kutambasula mfundo zomwe zimagwirizanitsa ndikukhazikitsa minofu yofooka. Zipiringizi zingathandizenso kutambasula ziwalo, makamaka usiku. Opaleshoni ya opaleshoni ingathe kuthetsanso kapena kukonza mavuto ovomerezeka.
Kujambula kwa ultrasound kapena computed tomography (CT) kanatanthawuze njira zosawerengeka za mitsempha. Izi zikhoza kapena siziyenera kuchitidwa opaleshoni kuti zichiritsidwe. Zokhumudwitsa za mtima zangwiro ziyenera kukonzedwa.
Kutsegula kwa AMC
Moyo wa munthu wokhala ndi arthrogryposis nthawi zambiri umakhala wabwino koma ukhoza kusinthidwa ndi zofooka za mtima kapena mavuto akuluakulu a mitsempha.
Kawirikawiri, zizindikiro za ana omwe ali ndi amyoplasia ndi zabwino, ngakhale kuti ana ambiri amafunikira thandizo labwino kwa zaka zambiri. Pafupifupi awiri mwa atatu aliwonse amatha kuyenda (kapena popanda chilolezo) ndi kupita kusukulu.
Zotsatira:
National Organization for Rare Diseases. Arthrogryposis Multiplex Congenita. Inapezeka pa Feb 13, 2016.