Uric acid , mankhwala osokonekera, ndiwo zotsatira za purine metabolism. Mitengo ndi mankhwala omwe amapezeka mthupi lathu komanso zakudya zathu. Kawirikawiri, uric acid umasungunuka m'magazi imakonzedwa kupyolera mu impso ndipo imachotsedwa ku thupi mumkodzo. Matendawa, omwe amadziwika kuti hyperuricemia (mkulu wa uric acid m'magazi), amatha kuchitika ngati kuchepa kwa uric acid kapena kuwonjezeka kwa uric acid.
Mankhwala a hyperuricemia angapangitsenso chifukwa chophatikizapo kugwiritsira ntchito mankhwala osokoneza bongo. Zomwe zimakhala pansi pafupipafupi zimayambitsa matenda ambiri a hyperuricemia. Kuwonjezera pa kuchuluka kwa mankhwala kumawerengetsa kuchuluka kwa matenda oopsa a hyperuricemia. Kufala kwa mavitamini (popanda zizindikilo) kuchuluka kwa chiwerengero cha anthu ambiri kumawerengeka kukhala pakati pa 2% ndi 13%.
Pafupifupi magawo awiri pa atatu aliwonse a urate thupi (uric acid) amapangidwa mosalekeza (mkati mwa thupi), pamene gawo limodzi la magawo atatu likuwerengedwa ndi metabolism ya purines. Pafupifupi 70 peresenti ya urate yomwe imatulutsidwa tsiku ndi tsiku imasokonezeka ndi impso, ndi zotsala zomwe zimachotsedwa m'matumbo.
Mayeso a Magazi a Uric
Njira yowonetsera magazi ya uric acid imakhala pakati pa 3.5 ndi 7.2 mg / dL. Muyenera kudziwa kuti ma laboratories osiyanasiyana akhoza kukhala ndi zigawo zosiyana zosiyana siyana. Hyperuricemia, makamaka, imatanthawuzidwa ngati mlingo wa magazi wa uric acid kuposa 7mg / dL kwa amuna ndi oposa 6mg / dL kwa akazi.
Uric acid Crystal Formation
Ngakhale kuti hyperuricemia palokha si matenda, ndipo nthawizina sichimawopsa, nthawi yaitali ya hyperuricemia ingayambitse chitukuko cha makristasi. Ndi ma crystals a uric acid omwe amagwirizana ndi gout. Koma, ngakhale podziwa zimenezo, mgwirizano pakati pa hyperuricemia ndi gout siwonekeratu.
Odwala ambiri omwe ali ndi matenda a hyperuricemia samakhala ndi gout - ndipo odwala ena omwe ali ndi matendawa amakhala ndi magazi ochepa kapena ochepa. Ndi ochepa chabe a anthu omwe ali ndi matenda oopsa omwe amapita patsogolo kuti akhale ndi gout.
Mafuta a Uric acid, akaikidwa pamalumikizidwe, amachititsa ululu wamodzi, kutseguka kwa palimodzi, kuuma kofanana, kuwonongeka kwa mgwirizano, ndi kuyenda kochepa. Ngati gout ikuphuka, malangizo a American College of Rheumatology pamayendedwe a gout (2012) amavomereza kuti ma uric asidi azisungidwa pa mlingo pansi pa 6 mg / dL kuti zisawonongeke.
Mafuta a Uric acid amatha kuperekanso mu impso. Mafuta a uric acid mu impso angachititse kuti impso zikhale zopangika ndipo zikhoza kuwatsogolera ku matenda a impso kapena impso kulephera.
Zinthu Zowopsa Zophatikizidwa ndi Mankhwala Opatsirana
Matenda a hyperuricemia amagwirizanitsidwa ndi ziwopsezo, monga dysglycemia (matenda a shuga a magazi), dyslipidemia (matenda a lipid), kunenepa kwambiri, ndi kuthamanga kwa magazi kosadziwika bwino. Mankhwala a hyperuricemia angadwale chifukwa chokhala ndi moyo wathanzi, makamaka zakudya zoperewera zomwe zimakhala ndi purines, mapuloteni, mowa, ndi zakudya.
Ngakhale kuli kofunika kumvetsetsa zinthu zomwe zingasinthe, monga zakudya ndi moyo, zomwezo ndizokwanira kuti zisawononge matenda a hyperuricemia.
Ndizozindikiranso kuti mankhwala ena angapangitse kuti pakhale chiopsezo cha hyperuricemia, kuphatikizapo thiazides, loop therapy, ndi aspirin yachepa.
Mfundo Yofunika Kwambiri
Nthaŵi yaitali ya hyperuricemia, kapena matenda opatsirana kwambiri, imakhudzidwa ndi chiopsezo chachikulu chokhala ndi gout. Kuchotsa Crystal ndi zotsatira za hyperuricemia zomwe zingayambitse matenda opatsirana ndi impso. Kusunga magazi a uric acid mlingo pansi pa 6 mg / dL ndi kofunika kuti anthu apeze kuti ali ndi gout kuti asamapeze zida zobwerezabwereza.
> Zotsatira:
> Uric acid - Magazi. MedlinePlus. 4/29/2013.
> Hyperuricemia Yosatha, Uric Acid Deposit, ndi Mavuto Okhudza Mtima. Grassi D. et al. Zamakono Zamakono. April 2013.
> Gout ndi Hyperuricemia. National Kidney Foundation.