Ngakhale Kuwonjezera Njira Zothandizira, Zotsatira Zakhala Zambiri Zosakaniza
Lipodystrophy yokhudzana ndi kachirombo ka HIV ndi chikhalidwe chodziwika ndi kugawidwa kwakukulu kwa mafuta a thupi. Matendawa amawoneka ndi kupopera kwa nkhope, matako, kapena mapeto, nthawi zambiri kumayambitsa mafuta pamimba, pachifuwa, kapena kumbuyo kwa khosi (kumapeto kwake kumatchedwa "buffalo hump" - monga maonekedwe).
Lipodystrophy yokhudzana ndi HIV yakhala ikugwirizana ndi mitundu ina ya mankhwala ochepetsa kachilombo ka HIV , kuphatikizapo protease inhibitors (PIs) ndi zina zotchedwa nucleoside reverse transcriptors (NRTIs) monga Zerit (stavudine) ndi Videx (didanosine) . Chikhalidwechi chikhoza kukhala chifukwa cha kachilombo ka HIV, makamaka kukhudza odwala omwe sanayambe kulandira ma ARV.
Ngakhale lipodystrophy ikuwoneka mochepa kwambiri kwa anthu omwe ali ndi kachilombo koyambitsa matenda a Edzi kuyambira pachiyambi cha ma antiretroviral, zakhalabe zovuta chifukwa chikhalidwe sichitha kusinthika ndipo chimapitirirabe ngakhale ngati mankhwalawa akuyimitsidwa.
Chithandizo cha Lipodystrophy Chithandizo: Njira ndi Maganizidwe
Ngakhale kuti palibe mankhwala okhudzana ndi lipodystrophy yokhudzana ndi kachilombo ka HIV, pali njira zothandizira mankhwala zomwe zingasinthe zotsatira zina za kugawidwa kwa mafuta, komanso kuthana ndi mavuto ena azaumoyo okhudzana ndi cholesterol ndi triglyceride m'magazi.
Zina mwa njirazi:
- Kugwiritsa ntchito mankhwala opatsirana pogonana kungathandize ngati dokotala akukhulupirira kuti mankhwala anu ndi omwe amachititsa kuti mupereke mafuta osayang'ana bwino. Kusintha mu mkhalidwe umenewu nthawi zonse kumalimbikitsidwa kuti muteteze kuwonjezereka kwa chikhalidwe. Ngakhale kuti pangakhale kusinthika kwa mkhalidwewu, makamaka kuwonongeka kwa nkhope (kumadziwika kuti lipoatrophy ya nkhope), zambiri zimasintha kukhala zochepa. Ndikofunika kudziwa kuti lipodystrophy nthawi zina imatha ngakhale pambuyo pa mapepala atayimitsidwa, ngakhale kuti nthawi zambiri nthawi zambiri zimakhala ndi nthawi.
- Kusintha kwa tenofovir kapena regimen yochokera ku tenofovir (mwachitsanzo, Truvada , Genvoya ) ingasinthe kachilombo ka nkhope, malinga ndi kafukufuku angapo. Ngakhale kuti sizingakhale zomveka, phunziroli limathandiza kugwiritsa ntchito tenofovir kapena abacavir ( Ziagen ) pakadwala kwambiri lipodystrophy popeza palibe mankhwala omwe amagwirizana ndi chikhalidwecho.
- Kufotokozera Egrifta (tesamorelin) panthawi ya kuchulukana kwa mafuta m'mimba ndi m'matumbo. Zochita zowonjezera zimavomerezedwa kuti azitha kulandira lipodystrophy yokhudzana ndi kachirombo ka HIV pamene ikukhudzana ndi kumanga mafuta a visceral pakatikati ndi pakati ndi ziwalo za m'mimba. Kuwongolera kumawoneka kukhalabe ndizing'ono, ngati zilipo, zowonongeka pa kuwonongeka / kugawidwa kwa mafuta pamaso, mabowo, m'mawere, kumbuyo kapena kumapeto.
- Zakudya ndi zochita masewera olimbitsa thupi sizikhala ndi zotsatira zoyenerera pa maonekedwe ena a lipodystrophy, koma amatha kuthandiza mosavuta mafuta omwe amapezeka ndi odwala opatsirana pogonana. Kuonjezerapo, iwo angathandize kuchepetsa zotsatira za matenda a lipodystrophy mwa kuwonjezera minofu yaumphawi pa mikono, miyendo ndi mabowo; kapena poyankha mavuto akuluakulu (mwachitsanzo, kunenepa kwambiri , matenda a kagayidwe kachakudya) komwe kumawonjezera kuwonjezeka kwa mafuta m'mimba, kumbuyo ndi mabere. Zakudya zochepa za mafuta ndi machitidwe olimbitsa thupi nthawi zonse zimalimbikitsidwa kwa anthu onse omwe ali ndi HIV, zazikulu kapena zazing'ono. Funsani katswiri wa zamaphunziro kapena katswiri wa zakudya kuti akuthandizeni kuti mukhale ndi zizoloŵezi zabwino zodyera.
- Tengani mankhwala ochepetsa kumwa mankhwala kuti muchepetse mayendedwe a triglycerides ndi cholesterol m'magazi anu. Kugwiritsa ntchito kwawo sikungathandize kusintha zotsatira za thanzi labwino (mwachitsanzo, kuchepetsa chiopsezo cha matenda a mtima ndi chitukuko cha shuga), zitha kuchepetsa kuopsa kwa lipodystrophy.
- Mankhwala opanga mahomoni amathandizanso pochiza lipodystrophy yokhudzana ndi kachilombo ka HIV, mwina ngati mawonekedwe a testosterone kapena opaleshoni pogwiritsa ntchito kukula kwa hormone-release hormone (GHRH). Pamene ntchito zonsezi zikugwirizana ndi kuwonjezeka kwa minofu, sizikudziwika kuti zimakhudza bwanji vuto lomweli. Kafukufuku wambiri amasonyeza kuti pali kusintha koyeso mugawidwe wa mafuta, ngakhale kuti zambiri zapindula zimatayika kamodzi kokha ngati mankhwala a hormone ayimitsidwa.
- Mankhwala otsekemera , omwe amadziwika bwino kwambiri kuti azigwiritsa ntchito zodzoladzola, amatha kuwongolera zina mwa maonekedwe a lipoatrophy, makamaka nkhope ndi mabowo. Mankhwala osokoneza bongo monga Sculptra (poly-L-lactic asidi) ndi Radiesse (calcium hydroxylapatite) amagwiritsidwa ntchito nthawi zambiri m'matendawa ndipo amafunikira chithandizo kangapo kamodzi pachaka, Ngakhale kuti cosmetically ingathandize ngati katswiri wodziwa bwino, ndalama zowonjezera zingakhale zoletsedwa kwa odwala ena.
- Liposuction kawirikawiri imafufuzidwa chifukwa chochotsa mafuta ochuluka kumbuyo kwa khosi (zomwe zimatchedwa kuti "njuchi"). Ngakhale mofulumira komanso mogwira mtima, pamakhala mwayi wokonzanso mafuta kumanga ngakhale pambuyo pa opaleshoni. Kuonjezera apo, kupaka mafuta amatha kuchotsa mafuta ochepa omwe ali pansi pa khungu, kutanthauza kuti kulemera kwa mafuta m'kati mwa mimba sikutheka kuchipatala. Ndipo monga momwe zimachitira opaleshoni yonse, liposuction imaphatikizapo ngozi .
Mulimonse momwe mungasankhire, musataye mankhwala anu a HIV musanalankhule ndi dokotala wanu. Onetsetsani kuti, kuphatikizapo dokotala wanu wa HIV mu zokambirana zilizonse zomwe mungakhale nazo ndi opaleshoni yokonza mavitamini pofuna kuthana ndi maonekedwe a lipodystrophy.
Chitsime:
National Institutes of Health (NIH). "Zotsatira Zachilombo za HIV: HIV ndi Lipodystrophy." AIDSInfo. Rockville, Maryland; zasinthidwa pa January 1, 2016.