Mipukutu yamlomo ikhoza kukhala chisonyezero cha matenda a HIV
Leukoplakia yaubweya (yomwe imadziwikanso kuti leimuplakia yamphongo ya m'kamwa, kapena OHL) imafala kwambiri m'mimba mwa anthu omwe ali ndi chitetezo chamthupi, chomwe chimakhala ndi zikopa zoyera kumbali ya lilime komanso maonekedwe a "tsitsi". Ndi imodzi mwa matenda ambiri omwe amatha kukhudza anthu omwe ali ndi kachilombo ka HIV, kawirikawiri pamene CD4 ya munthu imakhala pansi pa maselo 200 / mL.
OHL imayambitsa matenda a Epstein Barr (EBV), kachilombo ka banja la herpes lomwe limakhudza anthu pafupifupi 95%, ngakhale ambiri atha kukhala ndi kachilombo koyambitsa matenda omwe amalepheretsa kuti kachilombo kawonetsere. Komabe, kwa anthu omwe ali ndi kachilombo koyambitsa matenda a Edzi, chitetezo champhamvu chotetezedwa ndi matenda chimapangitsa oHL kukhala ndi mwayi wochuluka. Choncho, akuonedwa kuti ndi HIV yowonongeka.
Matenda a OHL ali abwino ndipo samayambitsa zizindikiro zina. M'malo mwake, chikhalidwechi chimasonyeza kuti munthu ali ndi chitetezo choteteza chitetezo cha mthupi komanso chidziwitso chowonjezeka kwa ena, OIs oopsa kwambiri. Kawirikawiri, OHL imawonekera mochuluka kwambiri mwa amuna kusiyana ndi akazi, ndipo sawoneka kawirikawiri ana.
Asanafike poyambitsa matenda opatsirana pogonana (ARV) , OHL anali kunena mwatsatanetsatane za kupita patsogolo kwa matenda otha msanga, omwe 47% anapitiliza kuchokera ku HIV mpaka Edzi m'zaka ziwiri.
Masiku ano, ndi chiyambi cha ART, chiwerengero cha OHL chatsopano kwambiri, mosiyana ndi zina zomwe zimagwiritsidwa ntchito ndi HIV zomwe zimakhala zolimba komanso zapamwamba pa ma CD4.
Pakalipano, kafukufuku waposachedwapa wasonyezeranso kuti kusuta , kuphatikizapo otsika CD4 count, kumabweretsa pafupifupi kuwonjezeka kawiri pa chiopsezo cha OHL.
Kuzindikira, Kuchiza ndi Kuteteza OHL
Matenda a OHL amasiyana kukula. Akhoza kupereka pambali imodzi kapena mbali zonse za lilime kapena mkati mwa tsaya. Kawirikawiri sizimapweteka pokhapokha pali kachilombo kawiri, kachilomboka.
Nthaŵi zina, zilonda zingayeseke, zomwe zimapangitsa kuti zikhale zovuta kusiyanitsa ndi zina, matenda omwewo. Komabe, mosiyana ndi candidiasis ya pakamwa (thrush) , OHL silingakhoze kufooka mosavuta kuchokera ku lirime. Izi, pamodzi ndi maina a mafinya amaoneka, ndizo makhalidwe omwe OHL akuonetsa kwambiri mwa anthu omwe ali ndi HIV.
Ngakhale kuyendera kachipangizo kawirikawiri kumapereka chithandizo choyenera, zotsatira zina zimapangitsa kuti 17% ya zovuta zowonongeka zisakwane. Ngati kuli kofunikira, chitsimikizo chotsimikizirika chikhoza kupangidwa ndi kuyesa kachipangizo kakang'ono ka njira zogonana ndi njira zina zothandizira kuti zitsimikizire matenda a EBV.
Chifukwa chakuti lesijekiti cha OHL chili ndi mphamvu, palibe mankhwala omwe amafunikira. Komabe, ena mwa iwo makamaka omwe ali ndi CD4 ochepa-dose Zovirax (acyclovir) angathandize kuthetsa vutoli. Ngakhale zili choncho, kuthamanga kwa OHL kumakhala kovuta pamene acyclovir mankhwala akuyimitsidwa pokhapokha ngati chitetezo cha mthupi chitabwezeretsedwa.
OHL ikhoza kubwereranso pamene mankhwala osokoneza bongo a HIV akukula ndipo mankhwala a antiretroviral odwala sagwira ntchito kwambiri poletsa HIV.
Kupewa OHL kumadalira kwambiri matenda opatsirana ndi kachilombo koyambitsa matenda a HIV, ndipo zotsatila zamakono za US zikuyambitsa kuyambitsa ART pa CD4 chiwerengero pakati pa 350 ndi 500 maselo / mL, ngakhale pa CD4 chiwerengero chapamwamba kuposa maselo 500 / ml.
Kusuta fodya kumalimbikitsidwanso pofuna kuteteza maonekedwe a OHL, komanso zina zambiri zomwe zimagwirizanitsidwa ndi HIV komanso zosagwirizana ndi HIV.
Zotsatira:
Katz, M .; Greenspan, D .; Westenhouse, J ;; et al. "Kupititsa patsogolo kwa Edzi kwa amuna omwe ali ndi kachilombo ka HIV komanso amuna ndi akazi omwe ali ndi ubweya wa leukoplakia wamphongo ndi mawu a candidiasis." AIDS. January 1992; 6 (1): 95-100.
Cherry-Tsabola, G ;; Daniels, C ;; Ofatsa, V .; et al. "Mawonetsetsedwe a pamlomo pa HAART." . Journal ya National Medical Association. February 2003: 95 (Supplement 2): 21S-32S.
Chattopadhyay, A .; Caplan, D .; Slade G ;; et al. "Kuwonjezeka kwa mankhwala a candidiasis ndi a m'kamwa mwaukali leukoplakia okalamba omwe ali ndi kachilombo ka HIV ku North Carolina." Kutsegula Mwamlomo Mlomo Wovomerezeka Mwamlomo. Opaleshoni Yamakono Mankhwala Odzudzula Mankhwala Opatsirana Mankhwala Opatsirana Mankhwala Opatsirana Opaleshoni Endodontology . January 2005; 99 (1): 39-47.
Chapple, I. ndi Hamburger, J. "Tanthauzo la thanzi labwino m'thupi la HIV." . Matenda opatsirana pogonana. August 2005; 76 (4): 236-243.