Kodi Mankhwala Othandiza Kwambiri Amtundu wa MALT Lymphoma?
Kodi chapamimba cha MALT lymphoma ndi chiyani?
Mwachidule
Gastric MALT lymphoma ndi mtundu wa non-Hodgkin Lymphoma (NHL) umene umakhudza mimba. Kuti mudziwe zambiri za zizindikiro ndi mayesero a lymphoma iyi, onani nkhani yokhudza MALT Lymphoma .
Kuchiza
Mankhwala otsatirawa angagwiritsidwe ntchito pa mimba ya MALT:
- Kuchiza kwa matenda a Helicobacter pylori (antibiotic)
- Kuchiza ma ARV
- Opaleshoni
- Chemotherapy
Nthawi zina, kuchotsa matenda amene alipo m'mimba kungakhale kofunikira, komabe nthawi zambiri chithandizo chamankhwala chimakhala chofunika kwambiri kuti chithandizo cha MALT chikhale chokwanira. Kwa odwala omwe ali ndi msinkhu wa kapangidwe ka H. pylori- wosakaniza mimba ya MALT lymphoma, njira yoyamba yothetsera vuto la H. pylori yotsatiridwa ndi kuyang'anitsitsa ikhoza kukhala sitepe yoyamba yisanafike poizoni. Pafupifupi oposa 20 mpaka 30 peresenti ya odwala samayankha kuthetsa mankhwala kapena kuwonetsa kubwezeretsa panthawi yotsatira, komabe.
Maantibayotiki
Ambiri ngati sangakhale odwala MALT lymphoma m'mimba amakhudzidwa kwambiri ndi matenda a H pylori. H. pylori ndi bakiteriya omwe amadziwika kuti amachititsa zilonda zam'mimba ndi zilonda zam'mimba . Monga momwe mabakiteriya angawononge chitetezo cha mmimba ndi matumbo kuti azipangitsa zilonda zam'mimba, zimaganiziridwa kuti zingayambitsenso kutupa m'mimba zomwe zingachititse khansa.
Popeza pafupifupi theka la anthu padziko lonse lapansi ali ndi mabakiteriya, matendawa amaoneka kuti samayambitsa mavuto kwa aliyense, ndipo mwina pali zinthu zina monga umoyo ndi moyo zomwe zimafunikira, mogwirizana ndi matenda a H pylori, kuti athetse mavuto.
Odwala omwe ali ndi MALT lymphoma omwe amayesanso chithandizo cha H pylori, ma antibiotics a H pylori angathetseretu khansa .
Pafupifupi 3 mwa anayi aliwonse omwe ali ndi matenda oyambirira, chithandizo cha H pylori chikhoza kuthetsa vutoli. Matendawa amakhalabe odwala ambiri. Anthu omwe ali ndi yankho lathunthu akhoza kulandiridwa mosalekeza, kapena kuyang'anitsitsa, ndi mapepala omaliza . Ngakhale kuti akukhululukidwa kwathunthu, anthu ena apitiriza kukhala ndi mayeso abwino a PCR kwa H. pylori.
Zapezeka kuti anthu ena amene amayesa matenda a H. pylori amachiza mankhwala ndi ma antibiotic ndi chikhululukiro chonse, kotero tinganene kuti pafupifupi aliyense amene ali ndi chapamimba cha MALT lymphoma ayenera kuchiritsidwa ndi mankhwala opha tizilombo kuti athetse H. pylori.
Mankhwala Opanga Mafuta
Mazira ndi mankhwala omwe amawakonda a MALT lymphoma pamene H pylori sakupezeka, kapena pamene mankhwala a anti H pylori alephera. Mankhwalawa amaperekedwa mochepa kwambiri, ndipo mankhwalawa nthawi zambiri amateteza lymphoma. Chithandizo cha mankhwala, chokha, chingathe kukwaniritsa kwathunthu odwala oposa 95% , ndipo odwala ambiri amakhalabe olamulira nthawi yaitali.
Opaleshoni
Kuchita opaleshoni ndi njira yabwino yothandizira ma lymphomas a MALT m'mimba ndipo amachititsa kuti odwala ambiri athe kulamulira nthawi yaitali. Zoopsa za opaleshoni ndi zazikulu kuposa za ma radiation, choncho opaleshoni siigwiritsidwe ntchito mochiritsira.
Monga radiotherapy, opaleshoni nthawi zambiri amawongolera ndi kuchiza ma lymphomas a MALT omwe amangokhala m'mimba.
Chemotherapy
Chemotherapy amagwiritsidwa ntchito poyambirira msinkhu wamatenda am'mimba a MALT pamene mankhwala am'deralo amalephera kuthetsa matenda, kapena pamene matendawa amatha. Kwa khansa yapakati yapamimba, chemotherapy ndi chithandizo cha kusankha. Mankhwala osiyana ndi othandizira ali ndi maimymimasi opita pang'onopang'ono.
Immunotherapy
Rituxan (rituximab) ndi anti-monoclonal antibody yomwe ili ndi lymphoma zambiri kuphatikizapo chapamimba cha MALT lymphoma. Monga matupi athu amapanga tizilombo toyambitsa matenda kumenyana ndi mabakiteriya ndi mavairasi, Rituxan kwenikweni ndi "munthu wopanga antibody " amene amagwira ntchito polimbana ndi maselo a khansa.
Monga momwe ma antibodies athu amadziŵira kuti amadziwika bwino pa mabakiteriya, mankhwalawa amadziwa chizindikiro china pamwamba pa maselo ena omwe ali ndi khansa.
Kulimbana ndi Kuthandizidwa
Mwamwayi, chapamimba cha MALT lymphoma ndi khansa yochiritsidwa kwambiri yomwe imakhala yabwino kwambiri. Icho chinati, kuti chingakhale chowopsya kuti chipezeke ndi khansara iliyonse. Kuwonjezera apo, mankhwala amatha kukhala ndi zotsatira, makamaka kutopa. Yesetsani kwa achibale anu ndi abwenzi anu , ndipo lolani anthu kuti akuthandizeni. Mukhozanso kufufuza malangizo awa omwe anthu adapeza othandizira kuthana ndi lymphoma .
Zotsatira:
Gisbert, J., ndi X. Calvet. Bwerezani mfundo: malingaliro olakwika omwe amagwirizanitsa ndi kayendedwe ka Helicobacter pylori-yogwirizana ndi mimba ya MALT-lymphoma. Pharmacology and Medical Therapeutics . 2011. 34 (9): 1047-62.
Nakamura, S., ndi T. Matsumoto. Njira Yothandizira Mankhwala a Mucosa-Associated Lymphoid Tissue Lymphoma. Zipatala za Gastroenterology za kumpoto kwa America . 2015. 44 (3): 649-60.
Nakamura, S., Sugiyama, T., Matsumoto, T. et al. Zotsatira za kuchipatala kwa nthawi yayitali za mimba ya MALT lymphoma pambuyo pochotsa Helicobater pylori: maphunziro osamalidwa a gulu lachiwerengero la odwala 429 ku Japan. Kutha . 2012. 61 (4): 507-13.