N-acetylcysteine, yomwe imadziwika kuti NAC, ndi antioxidant wamphamvu yomwe ingathandize amayi omwe akudwala sycystic ovary syndrome (PCOS). Mayiko ambiri akudziwika ku Ulaya kwa zaka makumi asanu ndi makumi asanu ndi makumi asanu ndi makumi asanu ndi awiri monga mankhwala othandizira kuteteza thupi komanso kutchuka kwa bronchitis, NAC ikuwoneka ngati chithandizo cholumikizira chothandiza kwa amayi omwe akuvutika ndi mavuto a PCOS. Nazi zotsatira zisanu zabwino za NAC kwa amayi omwe ali ndi vutoli.
Zimapangitsa kuti chiberekero chikhalepo
Kwa amayi pafupifupi 70 peresenti ya amayi omwe ali ndi PCOS omwe amavutika ndi kusabereka , NAC ikhoza kupereka chiyembekezo. Kupenda ndondomeko komanso kufotokozera mwachindunji komwe kunalembedwa mu Journal of Obstetrics ndi Gynecology kunayang'ana ubwino wa NAC mu mayesero asanu ndi atatu omwe amayendetsedwa mosavuta omwe amawaphatikizapo amayi 910 omwe ali ndi PCOS. Kuwunika kumeneku kunasonyeza kuti NAC inapereka chitukuko chochulukirapo pakukweza chiwombankhanga, kutenga mimba ndi kubala moyo poyerekeza ndi placebo wokha.
NAC yasonyezedwa kuti ili ndi mapindu ofanana ndi a metformin owonjezera mimba ya mimba, zokopa zokhazikika, komanso kusintha msambo nthawi zonse kwa amayi omwe ali ndi PCOS.
Kwa amayi omwe akulimbana ndi clomid, NAC ingathandize kuti ubale wawo ukhale wabwino. Mu kafukufuku wofalitsidwa mu European Journal ya Obstetrics, Gynecology, ndi Biological Reproductive, anapeza kuti ogwira ntchito a NAC anali ndi mlingo wokwanira wa ovulation oposa 9 ndipo amayi ambiri omwe ali ndi kachilombo koyambitsa matendawa amakhala oposa asanu kuposa amayi awo.
Kulimbitsa Kutsutsana kwa Insulini
NAC ikuwonekera ngati njira yodalirika kwa amayi omwe ali ndi PCOS kuti apititse patsogolo magulu awo a insulini. Chofunika kwambiri cha NAC ndicho kuteteza odwala matenda a insulini komanso kuchititsa kuti maselo osokonezeka a shuga asokonezeke. Chotsatira chake, NAC ikhoza kuchepetsa kuteteza insulini.
Ngakhale kuti FDA sivomerezedwa kuti igwiritsidwe ntchito, metformin imakhalabe mankhwala omwe amalembedwa kuti athe kuthandiza amayi omwe ali ndi PCOS omwe ali ndi insulin. Maphunziro angapo afanizira NAC ndi metformin mwa akazi omwe ali ndi PCOS. Akazi omwe anatenga NAC anasonyeza zotsatira zofananako ndi metformin pofuna kuchepetsa insulin kukana komanso kuchepetsa makilogalamu a kolesterol , ndipo popanda kuwona zotsatira zofanana za m'mimba zomwe metformin ingayambitse.
Kubwezeretsa Kusintha kwa Hormone
Phindu lodabwitsa la NAC ndiloti limatha kuchepetsa miyeso ya androgen ndikuyendetsa nthawi ya kusamba . Phunziro lawo, Oner ndi alongo akazi omwe ali ndi ma random omwe ali ndi PCOS kutenga metformin (500 mg, katatu pa tsiku) kapena NAC (600 mg katatu pa tsiku) kwa masabata 24. Zotsatira zonsezi zinachititsa kuti chiwerengero cha hirsutism chichepetse kwambiri, testosterone yaulere, ndi kusasamba kwa msambo.
Zimalimbana ndi kutupa
Azimayi omwe ali ndi PCOS awonetsedwa kuti ali ndi magawo apamwamba a nkhawa yauchilendo kuposa amayi opanda PCOS. Matenda apamwamba a kupsyinjika kwa mthupi akhoza kuwononga maselo ndikulimbikitsa kutupa komwe kumapangitsa kuti ziwonongeke kwambiri pa PCOS. Monga antioxidant amphamvu, NAC imayesetsa kulimbana ndi vuto lakumadzimadzi ndi kuchepetsa kutupa.
Amatithandiza Chiwindi
Nthawi zina amayi omwe ali ndi PCOS amapanga matenda osakondera a chiwindi .
Matenda a chiwindi amtunduwu amachokera ku high insulini ndi triglyceride ndipo akhoza kusintha ndi kusintha kwa zakudya zanu.
NAC yasonyezedwa kuti ikuthandizira kuthetsa chiwindi cha mafuta mwa amayi omwe ali ndi PCOS. Kafukufuku amene anafalitsidwa mu Hepatitis Monthly anasonyeza kuti akazi omwe ali ndi PCOS omwe anachiritsidwa ndi NAC (1200 mg / tsiku) kwa miyezi itatu adasintha kwambiri pakuchepetsa mayesero a chiwindi, chizindikiro cha chiwindi cha mafuta.
Zonsezi, NAC ndi zakudya zowonjezera zabwino zomwe zimapereka madalitso ambiri kwa amayi omwe ali ndi PCOS. Ngati mukufuna kuyesa NAC kuti muwone ngati zingakuthandizeni kutenga mimba kapena kuchepetsa zotsatira zowonongeka za PCOS monga mafuta a chiwindi ndi insulini kukana, lankhulani ndi dokotala wanu ndi olemba zakudya zowonjezera kuti muzindikire mlingo woyenerera kwa inu .
> Zotsatira:
> Javaneman F. Kufanizitsa pakati pa zotsatira za metformin ndi N-acetyl cysteine (NAC) pa zizindikiro zina zamagetsi ndi zamagulu a amayi omwe ali ndi polycystic ovary syndrome. Gynecol Endocrinol. 2015 Dec 10: 1-5.
> Manouchehr Khoshbaten. N-Acetylcysteine Amapangitsa Ntchito ya Chiwindi mwa Odwala Osaledzeretsa Odwala Matenda a Chiwindi. Hepat Mon. 2010; 10 (1): 12-16.
> Oner G et al. Kachipatala, matenda a endocrine ndi zotsatira zamagetsi za metformin vs N-acetyl-cysteine mwa amayi omwe ali ndi matenda a polycystic ovary. Yuro J Obst Gynecol Biol. Nov 2011; 159 (1): 127-131.
> Thakker D. N-acetylcysteine kwa polycystic ovary syndrome: kufufuza mwatsatanetsatane ndi kufotokozera mwachidule mayesero ochiritsidwa omwe amachitidwa mosavuta. Chosowa Gynecol Int. 2015; 2015: 817849.