Mmene Horoni Imathandizira pa Circadian Rhythms, Jet Lag, ndi Insomnia
Melatonin ndi mahomoni omwe amawoneka bwino omwe angathe kuthana ndi mavuto ena ogona kuphatikizapo kupopera magazi, kusowa tulo, ndi matenda osokoneza bongo. Phunzirani za thandizo ili lagona ndipo ngati zili bwino kwa inu.
Kodi Melatonin Ndi Chiyani?
Melatonin ndi hormone yomwe imabisidwa ndi chinangwa cha pineal, yomwe ili pafupi kumbuyo kwa ubongo pamwamba pa cerebellum ndi dera lotchedwa ventricle yachitatu.
Melatonin imapangidwa kuchokera ku amino acid yotchedwa tryptophan ndipo imapezeka m'magazi komanso mu cerebrospinal fluid imene imatsuka ubongo ndi msana. Monga hormone, imapereka zizindikiro kwa ziwalo zina ndipo zikuwoneka kuti zimathandiza kusintha kayendedwe ka thupi. Kukula kwa Melatonin kumachepa pamene munthu akula.
Melatonin imagulitsidwa ngati thandizo la kugona ndipo ikhoza kuphatikizidwa ngati chogwiritsira ntchito popangidwira. Amapezeka m'madzi otsika (nthawi zambiri 1 mpaka 3 mg), koma mapiritsi ena akhoza kukhala ndi mlingo wokwana 5 kapena 10 mg. Ndiyo hormone yokha yosavomerezeka yomwe imapezeka kugula ku United States.
Udindo wa Melatonin mu Circadian Rhythm
Mtundu wa circadian ndizochitika zachilengedwe za thupi ndi zamakhalidwe zomwe zimatha nthawi yayitali. Njirazi zikuphatikizapo zinthu monga kugona tulo komanso kusintha kwa kutentha kwa thupi, kuthamanga kwa magazi, ndi kutulutsa mahomoni ena.
Maselo a Melatonin akuwonjezeka pambuyo poyamba mdima ndi chisinkhu pakati pa usiku pakati pa 11 PM ndi 3 AM. Nthaŵi zina imatchedwa "hormone ya usiku" kapena "homoni yagona." Melatonin ikuwoneka kuti imalimbikitsa kugona ndipo ikhoza kuwonetsa nthawi yogona.
Kugwiritsira ntchito Melatonin Kuti Muthane ndi Mavuto a Kugona
Melatonin ingakhale yothandiza kuthetsa vuto la circadian zovuta zomwe chilakolako cha kugona chimasokonezeka panthawi yake, zomwe zimapangitsa kuvutika kugona (kugona tulo) kapena kugona kosayenera.
Pali zinthu zambiri zomwe zimawathandiza, monga:
- Kutopa kwapaulendo wandege
- Sinthani kugwila ntchito kugona
- Kugonjera kwa akulu akulu
- Matenda oyambirira a matenda ogona
- Matenda osachepera afupi
- Ukhungu, umene umalepheretsa kulingalira kwa kuwala kwachibadwa-mdima wamdima
Osati aliyense amapindula ndi ntchito ya melatonin, ndipo mlingo ndi nthawi ya ma ARV ndizofunikira kwambiri.
Zotsatira Zogwirizana za Melatonin
Pali zowonjezereka zotsatira za mankhwala alionse, kuphatikizapo mavitamini owonjezera monga melatonin. Ngakhale kuti simungakhale ndi zotsatira zoyipa zambiri - ndipo mwina simungakhale nawo - zina zomwe zikhoza kuchitika ndi izi:
- Mimba imagwa
- Kuchepetsa kusamala
- Amnesia (kukumbukira kukumbukira)
- Kupweteka pachifuwa
- Chizungu cha Circadian chisokonezo
- Kusokonezeka
- Kuponda
- Kutopa kwa masana
- Kusokonezeka kwakanthawi
- Kutsekula m'mimba
- Chizungulire
- Kugona
- Hallucinations
- Zoopsya
- Mutu
- Mahomoni amasintha
- Magazi a shuga
- Kuthamanga kwa magazi
- Lonjezerani kuthamanga kwa diso
- Kukhumudwa
- Maonekedwe amasintha
- Nausea
- Kuthamanga
- Paranoia
- Pruritus (khungu khungu)
- Kugonjetsa
- Tachycardia (kuthamanga kwa mtima mwamsanga)
- Sakani chisokonezo
Melatonin sichiyendetsedwa ngati mankhwala ndipo imapezeka papepala, komabe muyenera kufunsa dokotala kuti muwone kuti ndi yoyenera komanso yogwiritsidwa ntchito kuti mugwiritse ntchito zovuta zanu.
Chenjezo limalimbikitsidwa mukamagwiritsa ntchito melatonin pakati pa ana ndi amayi apakati.
Ngati mukuvutika ndi matenda osagona, lankhulani ndi katswiri wa kugona za mankhwala ena omwe angakhale othandiza kwa inu, kuphatikizapo chithandizo cha kugonana kwa abambo (CBTI).
Zotsatira
Brzezinski, A et al . "Zotsatira za melatonin yodalirika pa tulo: meta-analysis." Kugonana Kwachisanu 2005; 9: 41.
"Melatonin." Epocrates Rx Pro. Version 16.6, 2016. Epocrates, Inc. San Mateo, California.