Kodi Chilombo cha Hodgkin Lymphoma N'chiyani?

Kalekale Hodgkin lymphoma ndi nthawi yakale yomwe amagwiritsidwa ntchito pofotokoza gulu limodzi la mitundu iwiri ya matenda a Hodgkin. Onse pamodzi amaphatikizapo 95 peresenti ya matenda onse a Hodgkin m'mayiko otukuka.

Zigawo za mtundu wa Hodgkin Lymphoma

• Nodular Sclerosing Hodgkin Lymphoma (NSHL) - Iyi ndiyo mitundu yambiri ya Hodgkin lymphoma m'mayiko otukuka. Zimapezeka zambiri kwa achinyamata.

• Mixed Cellularity Hodgkin Lymphoma (MCHL) - Ichi ndicho chotsatira kwambiri ndipo ndi mtundu womwe ukhoza kuchitika pa msinkhu uliwonse.
• Lymphocyte Rich Classical Hodgkin Lymphoma (LRCHL) - Ichi ndichizolowezi chosadziwika ndipo chimakhala chofala pakati pa anthu okalamba.
• Lymphocyte Depleted Hodgkin Lymphoma (LDHL) - Iyi ndiyo njira yocheperako ya mtundu wa Hodgkin lymphoma ndipo imakhala yofala kwambiri kwa anthu okalamba komanso omwe ali ndi ziwalo zomenyera thupi. Ngakhale kuti mitundu ina imapezeka m'magulu amtundu wapamwamba, m'kati mwa thupi, mu LDHL amakhudzidwa mimba ndipo pangakhale kuphatikiza, chiwindi ndi fupa la fupa.

N'chiyani Chimasiyanitsa Matenda Achikale a Hodgkin?

Mu magawo onse a Hodgkin lymphoma, maselo a khansa ndi mtundu wosazolowereka wa maselo amtundu wa B omwe amatchedwa maselo a Reed-Sternberg. Iwo ali ndi mawonekedwe osiyana, omwe ali mosiyana ndi maselo ena alionse m'thupi. Akawoneka m'magulu a mitsempha, amawathandiza kupeza matenda a Hodgkin.

Zili zazikulu kwambiri, ndipo mawonekedwe a RS omwe ali ndi chithunzi cha galasichi amapereka maso a chikopa. Pali mitundu yosiyanasiyana ya maonekedwe amenewa, koma amadziwika mosavuta ndi wodwalayo. Maselo a RS ndiwo maselo a khansa, koma kutambasula kwa maselo a mitsempha kumakhala chifukwa cha maselo ena am'thupi oteteza mthupi.

Mankhwalawa a matenda a Hodgkin akale amasiyana kwambiri ndi mitundu ina ya maselo yomwe imapezeka m'magulu am'mimba omwe amapezeka.

Zizindikiro ndi Kuzindikira Matenda a Hodgkin Okalamba

Zizindikiro za lymphoma sizinali zosiyana kwambiri pakati pa mitundu iwiriyi, koma miyambo ya ma lymph node ndi malo omwe amadziŵika angakhale osiyana kwambiri. Zotsatira zake, zotsatira pambuyo pa chithandizo zingakhalenso zosiyana. Munthu wodwala matenda amatha kudziwa mtundu weniweni wa Hodgkin mwa kufufuza zitsanzo za lymph node biopsy pansi pa microscope.

Matenda achikale a Hodgkin amapangidwa ndi zizindikiro, kuyerekezera thupi, kupimidwa kwa maselo, kupima magazi, komanso nthawi zina ndi mayesero a mafupa. Izi zimayesedwa ndi dongosolo la Stots Coldwold ndikupatsidwa magawo a Gawo I kupyolera mu IV. Amaperekedwanso A ndi B chifukwa chokhala ndi bulky kapena ayi, kutanthauza kuti zotupa m'chifuwa ndizomwe zili ndi chifuwa kapena masentimita 10 kudutsa m'madera ena.

Kuchiza kwa Matenda a Classic Hodgkin

Kuchiza kwa matenda a Hodgkin akale kumadalira mtundu, masitepe ndi ngati ndizovuta, zizindikiro, zotsatira za labu, zaka, ndi thanzi labwino. Kawirikawiri, mankhwala a chemotherapy amaperekedwa, motsogoleredwa ndi mankhwala opangira mazira. Ngati palibe yankho la mankhwalawa, limatha kutsatiridwa ndi mankhwala enaake, mankhwala othandizira, kapena mankhwala omwe ali ndi monoclonal antibody brentuximab vedotin.

_Zotsatira:

_{Khansa: Mfundo ndi Zolemba za Oncology 7th Edition. Okonza: VT DeVita, S Hellman ndi SA Rosenberg. Lofalitsidwa ndi Lippincott Williams ndi Wilkins, mu 2005.}

_{Matenda a Hodgkin, American Cancer Society.}

_{Kuchiza matenda a Hodgkin akale, mwazomwe. American Cancer Society.}

_{Selo la Reed-Sternberg, Atlas of Pathology, Edition 3.}