Zizindikiro, Zomwe Zimayambitsa, ndi Zochiritsira Matenda a Miyambo ya Hodgkin ya Mixed Cellular
Kodi ndi zinthu zotani zomwe zimaphatikizapo maselo a Hodgkin lymphoma, zomwe zimakhala zachilendo, chomwe chimayambitsa, ndipo zimachiritsidwa bwanji?
Mwachidule
Matenda osakanikirana a Hodgkin's lymphoma ndi mtundu wa matenda a Hodgkin , khansa ya maselo amphamvu kwambiri. Ndilo kachirombo kawiri kawiri ka matenda a Hodgkin , ndipo pafupifupi 15 mpaka 30 peresenti ya anthu onse omwe akudwala Hodgkin lymphoma kumadzulo ali ndi mtundu uwu.
Chiwerengero cha odwala omwe ali ndi mtundu uwu wa Hodgkin ndi chapamwamba kwambiri m'madera ena padziko lapansi kunja kwa United States, kuphatikizapo Asia. M'madera ena, ndiwo mtundu wamba wa Hodgkin lymphoma.
Zizindikiro
Hodgkin amatha kuchitika pa msinkhu uliwonse, ngakhale kuti ndi ofala kwambiri pakati pa anthu akuluakulu a zaka zapakati pa 55 ndi 74, komanso ana omwe ali ndi zaka zapakati pa 14. Ndizofala kwambiri kwa amuna ndi akazi. Mtengo wa mtundu uwu wa lymphoma zikuwoneka kuti wafika pa chiŵerengero pakati pa 1992 ndi 2011, koma izi zikhoza kukhala chifukwa cha momwe ma lymphomas amalembedwera mmalo mwa kuchepa kwenikweni kwa zochitika.
Ndizofala kwambiri kwa anthu omwe ali ndi chitetezo cha mthupi chomwe chikugwira ntchito molakwika, mwachitsanzo, mwa anthu omwe ali ndi HIV.
Zimayambitsa
Sidziŵika chomwe chimayambitsa matenda a Hodgkin , ngakhale kuti pali zifukwa zina zomwe zimawopsyeza. Ndi mitundu yosiyanasiyana ya mtundu wa lymphoma pali Epstein-Barr omwe amakhalapo pa maselo a khansa, koma asayansi sakudziwabe za mgwirizano womwe ulipo pakati pa mafupa ndi kachilombo kamene kamayambitsa matenda a mononucleosis.
Zizindikiro
Zizindikiro zazikulu zokhudzana ndi matendawa zimakhala ndi maselo akuluakulu m'khosi, pamimba komanso pamimba.
Ziwalo zina sizingagwirizane ndi mtundu uwu wa lymphoma kuposa mitundu ina ya lymphoma. Ndili ndi matenda osokoneza bongo, anthu 30 mwa anthu 100 alionse amakhala ndi nthendayi, 10 peresenti ya mafupa awo, 3 peresenti ya chiwindi, ndipo anthu 1 mpaka 3 peresenti ali ndi ziwalo zina.
Kudziwa
Matenda a lymphoma amapangidwa ndi lymph node biopsy .
Chithandizo
Anthu ambiri omwe ali ndi lymphoma imeneyi amapezeka ndi matenda apamwamba kwambiri, omwe amapezeka m'magulu awiri kumtunda kwa thupi komanso m'mimba.
Kwa anthu omwe ali ndi matenda oyambirira , chithandizochi chimaphatikizapo kuphatikiza mankhwala a chemotherapy ndi mankhwala odzola.
Ndi matenda opatsirana , nthawi zambiri mankhwala amatha kukhala ndi mankhwala enaake, ndipo nthawi zambiri sagwiritsidwa ntchito pogwiritsa ntchito mankhwala opatsirana pogwiritsa ntchito mankhwala. Mankhwala a Chemotherapy akufotokozedwa m'nkhaniyi yokhudza chithandizo cha Hodgkin lymphoma .
Kwa anthu omwe ali ndi kachilombo koyambitsa matenda a Hodgkin lymphoma, kapena ngati mankhwala oyamba akulephera, pali njira zingapo. Imodzi ndiyo kugwiritsa ntchito salvage chemotherapy (chemotherapy yogwiritsira ntchito kuchepa mphamvu ya chotupa koma osati kuchiza khansara) ndikumbuyo ndi mankhwala akuluakulu a mankhwala a dose komanso autologous stem transplant. Zosankha zina zingaphatikizepo ntchito ya monoclonal antibody Blincyto (brentuximab, ) immunotherapy ndi checkpoint inhibitor, kusakanikirana kosapanga maselo osagwiritsidwa ntchito, kapena kuyesedwa kwachipatala.
Kuthamangitsani
Ngakhale kuti maselo osakanikirana a Hodgkin lymphoma ndi khansa yamphamvu, zizindikirozi ndi zabwino kwambiri . Ziri zofanana ndi anthu omwe ali ndi nodular sclerosing Hodgkin lymphoma , ndipo ndi abwino kusiyana ndi anthu omwe ali ndi matenda a Hodgkin omwe amachititsa kuti thupi lawo liwonongeke.
Kulimbana
Ziribe kanthu kuti matendawa ndi owopsya kuti apezeka ndi khansara. Kuonjezera apo, mankhwala oika mtundu uwu wa matenda a Hodgkin mu chikhululukiro angakhale ovuta komanso okhometsa msonkho, ndipo tikuphunzira kuti kusokonezeka sikuli lingaliro labwino kwa anthu omwe ali ndi mitsemphama . Pitani kwa achibale ndi abwenzi. Ganizirani kulowetsa gulu lothandizira m'dera lanu kapena pa intaneti. Ndipo onani ndondomeko izi pa kuthana ndi lymphoma
Zotsatira:
Ansell, S. Hodgkin Lymphoma: Kuzindikira ndi Chithandizo. Mayo Clinic Proceedings . 2015. 90 (11): 1574-83.
Bienemann, K., Borkhardt, A., Klapper, W., ndi I. Oschies. Matenda akuluakulu a Epstein-Barr (EBV) -yomwe imakhala yotchedwa Hodgkin lymphoma ndi Hodgkin yofanana ndi B-cell yomwe imayambitsa matenda a EBV. 2 Mwa ana omwe ali ndi vuto la interleukin-2 losavomerezeka la T-cell kinase. Matenda Ake . 2015. 67 (5): 607-16.
Khansa: Mfundo ndi Zolemba za Oncology 7th Edition. Okonza: VT DeVita, S Hellman ndi SA Rosenberg. Lofalitsidwa ndi Lippincott Williams ndi Wilkins, mu 2005.
Glaser, S., Clarke, C., Keegan, T., Change, E., ndi D. Weisenburger. Zotsatira za Nthawi Zowonjezera za Hodgkin Lymphoma Histologic Subtypes: Kusintha Kwenizeni Kwenikweni Kapena Kusintha Zochita Zowononga? Khansa Epidemiology Zida ndi Kupewa . 2015. 24 (10): 1474-88.
National Cancer Institute. Kuyang'anitsitsa, Epidemiology, ndi Mapeto a Mapulogalamu. Mitundu yambiri yamakono ya Hodgkin lymphoma. Inapezeka pa 02/11/16. http://seer.cancer.gov/seertools/hemelymph/51f6cf57e3e27c3994bd5342/