PET / CT imathandizira phazi la Hodgkin Lymphoma moyenera
Mankhwala a khansa ndi khansa yokhudzana ndi mitundu ya maselo oyera a m'magazi otchedwa lymphocytes. Mafupa amtunduwu amadziwika kuti ndi Hodgkin kapena maselo am'thupi omwe si a Hodgkin .
Pali mitundu isanu ya Hodgkin lymphoma, kapena HL. Mawu akuti classical HL amatanthauza mitundu inayi yowoneka bwino: nodular sclerosing HL, wothandizira maselo a HL, olemera olemera omwe ali ndi ma lymphocyte ndi HL.
Mtundu wachisanu ndi waukulu wa HL, ndipo sutengedwa ngati HL.
Zizindikiro . Anthu omwe ali ndi HL akhoza kukhala ndi zizindikiro zosiyana, koma chizindikiro chofala kwambiri chimakhala ndi ma lymph node kapena zina. Mafupa amphongo amatha kukulitsa m'khosi, kumimba, kapena kubuula, kapena mkati mwa chifuwa. Kawirikawiri, anthu omwe ali ndi Hodgkin lymphoma, kapena HL, amatha kulemera, kutentha thupi, kuyabwa kapena kutaya thukuta usiku - onse omwe amatchedwa "B zizindikiro." Kukhalapo kwa chimodzi mwa zizindikirozi kumakwaniritsa kukhala ndi zizindikiro za B.
Zowopsa . Kukhala ndi chiopsezo sikukutanthauza kuti mumakhala ndi HL. Ndipotu, anthu ambiri omwe ali ndi HL alibe zidziwitso zosadziwika. Zizindikiro zomwe zimadziŵika zimaphatikizapo matenda opatsirana mononucleosis, kapena mono ; zaka zapakati zakale za HL zili m'zaka za m'ma 20s ndi 70s / 80s; mbiri ya banja; maziko apamwamba a chikhalidwe cha anthu; komanso kachirombo ka HIV.
Kusanthula ndi Kusinthana . Malingana ndi American Cancer Society, madokotala angasankhe njira zosiyanasiyana kuti atenge chitsanzo cha minofu, kapena biopsy, kuti ayesedwe ndi kufufuza kwakukulu.
Pamene PET / CT ikupezeka, imagwiritsidwa ntchito popanga. Mapulogalamu a PET / CT amagwirizanitsa CT ndi PET, kapena positron emission tomography pofuna kudziwa momwe khansara yafalikira komanso kukula kwake.
Za PET ndi PET / CT
PET amagwiritsa ntchito mawonekedwe a shuga, kapena a FDG, omwe amatengedwa, makamaka, ndi maselo a Hodgkin lymphoma bwino, kapena monga madokotala amati, ndi changu chachikulu.
Malingana ndi sayansi, mawonekedwe a radiation ali ofanana ndi a x-rays, komabe, kuphatikiza pamodzi ndi PET-CT kumakhala pafupifupi 10-20 kuposa kuchuluka kwa x-ray. Kusanthula kotereku kumagwirizanitsidwa ndi zopindulitsa komanso kuopsa kwa chiwopsezo chachikulu cha khansa ndi khansa. Choncho, chiŵerengero cha pangozi chiyenera kuwerengedwa mosamala kwa munthu aliyense musanaphunzire.
Kuyezetsa PET nthawi zambiri kumakhala kovuta kuposa CT pakuzindikira lymphoma. Mwachitsanzo, PET ikhoza kuwonetsa matenda mu maselo akuluakulu omwe amatha kuyeza matenda omwe ali kunja kwa maselo, koma osati pa CT. PET nthawi zambiri imaphatikizidwa ndi CT kuti zitheke kuyerekezera malo omwe ali ndi mphamvu zowonjezereka pa PET kufufuza ndi maonekedwe ambiri a dera la CT. Poyerekeza ndi kujambula kwachilendo, kugwiritsa ntchito PET / CT pazitsamba zoyambira kungakhudze machitidwe ndikutsogolera mankhwala osiyanasiyana.
PET / CT ya Hodgkin Lymphoma
Malangizo ochokera ku National Comprehensive Cancer Network amalimbikitsa kugwiritsa ntchito PET / CT kuti ayambe kuyanjanitsa komanso kutsiriza kuyankhidwa kwa odwala omwe ali ndi HL. Chifukwa PET / CT ndi yabwino kuyendetsa ndi kuyankha poyesa nthawi ndi pambuyo, ndikugwiritsanso ntchito kuyesa kupititsa patsogolo mankhwalawa.
Pokhala ndi odwala ochulukirapo akuyesera mayesero a kachipatala, kulingalira kwa nthawi yaying'ono kungagwiritsidwe ntchito kwa mitundu yosiyanasiyana ya malungo, kuphatikizapo HL, kuyesa kufotokozera kufunikira kochiritsira chosiyana koma sikunalimbikitsidwe pakalipano.
PET / CT ndi yabwino kwambiri pozindikira maselo omwe ali nawo ndi Hodgkin lymphoma. Ndibwino kuchepetsa matenda m'mfupa ndi ziwalo zina. Gawo la HL limadalira chiwerengero cha malo omwe amapezeka ndi maselo am'mimba komanso zochitika zina. Kafukufuku wasonyeza kuti mphamvu yowonjezera ya PET / CT imapangitsa odwala 10 kapena 15 peresenti ya odwala omwe ali ndi HL kuti asinthidwe kupita patsogolo kwambiri.
Choncho, odwala ambiri angakhale akuchiritsidwa.
Ndi mankhwala opatsirana pogwiritsa ntchito mankhwala omwe nthawi zambiri amalinganiza odwala HL oyambirira, PET / CT ili ndi mwayi winanso. Nthawi zina, kufotokoza momveka bwino komwe kumayambira kumadera kapena malo oyamba kumathandiza madokotala akukonzekera mankhwala odzoza mazira kuti awononge dera laling'ono, zomwe zingawononge minofu yathanzi.
PET / CT mu Chithandizo ndi Mafupa
Hodgkin lymphoma ndi imodzi mwa mitundu yambiri ya lymphoma yomwe imatengedwa kuti ndi yophedwa kwambiri. Kuwonetsa masewera olimbitsa thupi pamene thupi lili ndi lymphoma lilipo ndi kukula-ndilofunika kwambiri mu HL, osati chifukwa chakuti limathandiza kudziwitsa chigamulo cha mankhwala, komanso chifukwa kumathandiza kufotokozera zazomwe zimachitika.
Odwala omwe ali ndi matenda oyamba msinkhu amatha kulandira chithandizo cha mankhwala okhaokha, pamene ali ndi matenda apamwamba kwambiri, chemotherapy amaperekedwa ndipo mankhwalawa akhoza kugwiritsidwa ntchito kwambiri pofuna kuthetsa matenda, malinga ndi Hutchings ndi anzake.
Odwala akulu omwe ali ndi matenda oyamba msinkhu amakhala ndi moyo wopitirira 90 peresenti m'mayesero ambiri. Pa matenda opambana kwambiri, moyo wonse ndi 65-80 peresenti. M'madera onse oyambirira komanso matenda otukuka kwambiri, kugwiritsidwa ntchito motsatira zifukwa zoopsa kumachitika nthawi zambiri.
Kuphatikiza pa miyeso yeniyeni yeniyeni, PET / CT ingathandize kupeza matenda omwe atsalira pambuyo pa chithandizo. Izi zingakhale zothandiza, mwachitsanzo, pamene pali misala, kapena kutambasula m'chifuwa ndipo sizikuwonekeratu ngati zikuwonetsa matenda a scarring kapena yogwira ntchito.
> Zotsatira:
> American Cancer Society. Kodi ndizifukwa ziti zomwe zimayambitsa matenda a Hodgkin?
> Kumbukirani RT, Advani RH, Ai WZ, et al. Hodgkin lymphoma. J Natl Compr Canc Netw . 2011; 9 (9): 1020-1058.
> Hutchings M. Kodi PET / CT imathandiza motani pakusankha mankhwala kwa odwala Hodgkin lymphoma? Hematology Am Soc Hematol Pulogalamu Yophunzitsa . 2012; 2012: 322-7.
> Townsend W, Linch D. Hodgkin's lymphoma kwa akuluakulu. Lancet . 2012; 380 (9844): 836-47.