Kodi ali otetezeka kuchiza mphumu?
Bungwe la US Food and Drug Administration (FDA) lachenjeza odwala omwe amamwa mankhwala monga Dulera, Advair, Symbicort, Breo, Foradil, ndi Serevent. Kafukufuku wina, mayeso a SMART, adawonetsa ngozi yowonjezera ya imfa ya matenda a mphumu ndi mavuto ena opuma poyerekeza ndi placebo kwa odwala omwe amatenga Serevent, makamaka odwala ku Africa ndi America.
Pa chifukwa ichi, a FDA apereka machenjezo a mdima wakuda kwa mankhwalawa, mlingo waukulu kwambiri wa chenjezo kwa mankhwala omwe FDA angapereke.
Serevent ndi Foradil ndi agonist (LABAs) omwe amagwiritsidwa ntchito pochiza matenda a mphumu. Ma LABA sali oyenerera ochizira okha omwe amawoneka kuti ali ndi mphumu, ndipo amatha kuyambitsa masoka a mphumu ngati akugwiritsidwa ntchito okha. Munthu amene ali ndi mphumu ayenera kugwiritsa ntchito corticosteroid yosakanizidwa (monga Flovent, Pulmicort, QVAR) pochiza mphumu pamene LABA ikufunika. Dulera, Advair, Breo, ndi Symbicort ali ndi steroid yosakanizidwa komanso LABA.
Mwamwayi, yesero la SMART silinayankhe ngati wodwala wina akudwala corticosteroid chifukwa cha mphumu yawo - ichi chinali chisankho cha dokotala wa wodwalayo. Ambiri mwa odwala omwe ali ndi mphumu yovuta kwambiri sanatenge corticosteroid yosakanizika pamene aikidwa pa LABA.
Phunzirolo litayang'ana odwala omwe ankatulutsa corticosteroid komanso odwala LABA (monga Dulera, Advair, Symbicort ndi Breo), sichidawoneke ngati chiopsezo chachikulu cha matenda a mphumu kapena imfa ya mphumu.
A FDA tsopano akunena kuti mankhwala a LABA sayenera kugwiritsidwa ntchito ngati munthu amene ali ndi mphumu amayendetsedwa ndi corticosteroid yokhayokha.
Ngati mphumu siidayang'aniridwa pa steroid yosakanizidwa, zosankha zina zowonjezera ndizo: (a) kuwonjezera mlingo wa corticosteroid (yomwe ikhoza kukhala yoopsa ) kapena (b) Kuwonjezera kwa mankhwala ena monga LABA, Singulair , theophylline, mankhwala a prednisone ndi / kapena Xolair . Kumbukirani kuti mphumu yosatetezedwa ili ndi zoopsa zake, zomwe zingaphatikizepo mavuto aakulu, omwe amawopsyeza moyo wa mphumu .
Kwa anthu ambiri, phindu la corticosteroid ndi mankhwala a LABA (Dulera, Advair, Breo, ndi Symbicort) amaposa zoopsa. Komabe, ndikofunika kuti mudziwe kuopsa ndi phindu la mankhwalawa kuti muthe kusankha mwanzeru. Ngati mwakhala mukugwiritsa ntchito mankhwala a LABA monga gawo la mankhwala anu a mphumu ndipo mukuda nkhawa pazomwe zili pamwambapa, chonde MUSALANI kumwa mankhwala anu a mphumu mpaka mutalankhula ndi dokotala wanu. Ngati mutasankha kugwiritsa ntchito LABA monga gawo la mankhwala anu a mphumu, chonde auzeni dokotala wanu chisankho ichi musanayambe kumwa mankhwala a mphumu.
Onani makalata ochenjeza a FDA pa mankhwala omwe ali ndi LABAs.
> Zotsatira:
> Aaronson DW. Zilonda za "Black Box" ndi Mankhwala Osokoneza Bongo. J Zachilombo Zamtundu wa Immunol. 2006; 117: 40-4.Nelson HS, Weiss ST, Bleeker ER, et al. Salmeterol Multicenter Pulofesa Wofufuza za Phumu. Chifuwa. 2006; 129: 15-26.
> Nelson HS. Beta-Ochita Zakale Pakati pa Aphungu Ambiri: Umboni wakuti mankhwalawa ndi otetezeka. Primary Respiratory Care Journal. 2006; 15: 271-77.