Zotsatira za Statin Zikutanthauza Malo Otsutsa-Kutupa, Zopindulitsa Zina
Mavitamini otsika kwa cholesterol monga Lipitor (atorvastatin) ndi Crestor (rosuvastatin calcium) ndi ena mwa mankhwala operekedwa kwambiri pamsika lero. Cholinga chawo ndi kuchepetsa mafuta a cholesterol mwa kuchepetsa kuchuluka kwa cholesterol yotengedwa ndi chiwindi, koma amakhala ndi zotsatira zina zingapo. Ndi kugwiritsa ntchito nthawi zonse, sangathe kuchepetsa "cholesterol choipa" ( LDL ) komanso magulu a triglyceride .
Amatha kuonjezera "ma cholesterol" anu ( HDL ), nawonso.
Kafukufuku wasonyeza kuti zotsatira zowonjezera za statins pa cholesterol sizingakhale zopindulitsa zokha. Statin therapy yasonyeza malonjezano pa chirichonse kuchokera kumalimbana ndi matenda opatsirana pogonana pofuna kuteteza diso ku nthendayi.
Proper Anti-Inflammatory Properties of Statins
Monga cholesterol, kutentha kwa mitsempha yamakono ndi chimodzi mwa zinthu zingapo zomwe zingayambitse matenda a mtima ndi zikwapu. Mapuloteni a C-reactive (CRP) ndi chizindikiro chachikulu cha kutupa kovulaza, ndipo kugwiritsa ntchito statin kumathandiza kuchepetsa ma CRP.
Kafukufuku wofalitsidwa mu 2007 anawunika zotsatira za mayesero ambiri omwe anadwala odwala angioplasty omwe amatenga zilembo. Iwo adapeza kuti ziwerengero za CRP zinali zothandiza ngati " cholesterol " m'maganizo pofotokoza chiopsezo cha odwala pa zochitika za mtima.
Matenda a Antiviral ndi Antibacterial a Statins
Imodzi mwa zotsatira zodabwitsa kwambiri za ntchito ya statin ndizooneka ngati ziphuphu.
Kafukufuku wa ku Canada wa 2004 adapeza kuti ma statins anatsutsa chigwirizano cha kachirombo ka HIV ku maselo omwe angakhale nawo.
Kafukufuku wa 2005 wa odwala odwala 700 omwe akuchiritsidwa chifukwa cha chibayo anapeza kuti chiŵerengero cha imfa chinali choposa kawiri kuposa omwe sankagwiritsa ntchito statins.
Mu 2006, kafukufuku wina ku Canada anafufuza kuchuluka kwa sepsis , matenda oopsa a magazi, pakati pa odwala omwe anali kuchipatala chifukwa cha zochitika za mtima.
Zaka ziwiri zitatha iwo akugonekedwa m'chipatala, ogwiritsira ntchito statin anali ndi chiwerengero cha 19% poyerekeza kuposa awo osagwiritsa ntchito statin.
Kafukufuku wa kafukufuku wazaka 22 wa 2009 adapeza kuti ma statins adawoneka kuti apindula ndi zotsatira za matenda, koma sakanatha kumaliza.
Ma Statins May Lower Blood Pressure
Kugwiritsiridwa ntchito kwa Statin kumawonekeranso kuchepetsa kuthamanga kwa magazi, ngakhale modzichepetsa, omwe sali okwanira kuti azitsutsana ndi mankhwala omwe alipo pakamwa.
Kafukufuku wina wa ku Britain mu 2007 adanena kuti pakati pa ogwiritsira ntchito abambo, kuwerenga kwacheperachepera 1.9 mmHg kwa systolic blood pressure ndi 0.9 mmHg kwa diastolic magazi. Magulu awa a kuyeza kwa zovuta za magazi amaimiridwa ndi "yoyamba" kapena "nambala yapamwamba" yosonyeza kuwerenga kwa systolic ndi chiwerengero cha "chachiwiri" kapena "pansi" chosonyeza kuwerenga kwa diastolic. Kwa odwala omwe kuthamanga kwa magazi kunayamba kutsika kwambiri, zizindikiro zinaonekera kuti zipangitse dontho la 4.0 mmHg muzitsulo.
Kuchepetsa Kukhumudwa Kwambiri Ndi Matenda Aakulu Pambuyo pa Opaleshoni ya Mtima
Kugwiritsira ntchito matenda a atrial (AF) ndi chizoloŵezi cha mtima chosagwiritsidwa ntchito kawirikawiri pambuyo pa opaleshoni ya mtima. Izi zingabweretse kuchipatala chokwanira kapena ngakhale kukwapulidwa kapena mtima wosalimba. Mu kafukufuku wa 2006, odwala amene anapatsidwa sukulu ya statins pamaso pa opaleshoni anali 61% pangozi ya AF.
Matenda a Alzheimer Chitetezo ndi Malemba Osatsutsika
Umboni wina umasonyeza kuti mankhwalawa amatha kulepheretsa matenda a Alzheimer . Mu phunziro la 2007. Komabe, kafukufuku wofalitsidwa chaka chimodzi pambuyo pake, adatsata odwala okhala ndi zaka zoposa 12, sanapeze kusiyana kwakukulu pakati pa anthu omwe anatenga zilembo ndi omwe sanatero. Phunziro la 2014 la maphunziro anai, kuphatikizapo mayesero awiri akuluakulu osasinthika, sanapeze umboni wakuti ma statins anathandizidwa ndi chidziwitso cha maganizo aumtima.
Kodi Ndizolemba Zolondola Kwa Inu?
Ngati muli ndi cholesterol chokwanira, dokotala wanu angakupatseni mankhwala osokoneza bongo.
Komabe, zilembo zingakhale zosayenera kwa aliyense, choncho lankhulani naye ngati akuyenera kapena ayi, chifukwa chake, ndi zina zomwe mungasankhe.
Zotsatira:
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Patti, G., Massimo Chello, Dario Candura, Vincenzo Pasceri, Andrea D'Ambrosio, Elvio Covino, Germano Di Sciascio. "Kusinthika Kwambiri Kwambiri kwa Atorvastatin Kuti Kuchepetsa Matenda Opatsirana Kwa Atrial Postoperative Akudwala Odwala Opaleshoni Yopereka Mafupa." Kudutsa . 114: 14 (2006): 1455-461. 29 Sep. 2008
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