Mankhwala ogwiritsidwa ntchito kuti aswe ndi kumasula ntchentche mu COPD
Chimodzi mwa zinthu zazikulu za matenda osokoneza bongo (COPD) ndi kupangika kosavuta m'mapapo. Kuperewera kwa mankhwalawa, komwe nthawi zina kumatchedwa kuti mucus hypersecretion, kumachitika chifukwa cha kutupa kwa nthawi yaitali komwe kumawonjezera chiwerengero ndi kukula kwa zomwe zimatchedwa "maselo a chigoba" zomwe zimayendera mavesi a mlengalenga.
Ngakhale maselo amtunduwu amatha kusungunula ntchentche ngati njira yotetezera, ndi COPD kupanga zochulukirapo kungathe kutsegula ndimeyi, kuzipangitsa kuti kukhale kovuta kupuma.
Njira imodzi yochotseramo mankhwalawa ndi mankhwala osokoneza bongo kapena amphongo omwe amachititsa kuti azisokoneza. Mucolytics amagwira ntchito mwa kuthetsa zida zamagetsi mkati mwazitsekedwazo, kuziphwasula kotero kuti zikhoza kukwera mosavuta.
Ngakhale kuti mankhwala osokoneza bongo saganiziridwa kuti ndi mbali yowonongeka kwa chithandizo cha COPD , malangizo a 2017 omwe amaperekedwa ndi Global Initiative for Obstructive Lung Disease (GOLD) amasonyeza kuti angakhale othandiza kwa anthu osalandira corticosteroids .
Chidule cha Mucolytic Mankhwala Pochiza COPD
Mucolytics ingatengedwe pamlomo kapena pulogalamu ya mankhwala kapena nebulazer . Zina mwa mitundu yowonjezereka yogwiritsidwa ntchito mu COPD ndizo:
- Carbocysteine
- N-acetylcysteine
- Erdosteine
- Mecysteine
- Guaifenesin
- Bromhexine
Njira yothandizira ikhoza kusiyana ndi mankhwala. Mwachitsanzo, Carbocysteine imagwiritsa ntchito maselo ofooketsa mphamvu komanso imapereka mankhwala othandiza antioxidant komanso anti-inflammatory.
N-acetylcysteine, mosiyanitsa, imathyola mgwirizano womwe umagwirizanitsa ntchentche palimodzi ndikusintha kusayenerera kwa okosijeni ndi antioxidants.
Zotsatira zake zingasinthenso mosiyana ndi mtundu wa mankhwala ndi kutulutsidwa. Kawirikawiri, kusuta ndi kutsekula m'mimba ndi mbali yowonjezera yowonjezera yokhudzana ndi mapiritsi, pamene zizindikiro zamadzimadzi zimayambitsanso matenda osokoneza bongo.
Maonekedwe a Nebulized amachitanso chimodzimodzi kupweteka, kumphuno, komanso kupanga mapepala oyera m'milomo.
Mwachidziwikire, anthu amene amatha kuwonetsa chiopsezo amaonedwa kuti ndi otetezeka ndipo amagwirizana ndi chiopsezo chachikulu cha zochitika zovuta kwa anthu omwe ali ndi COPD. Pomwe zikunenedwa, ndizofunika nthawi zonse kuyankhula ndi adokotala za zotsatira, zotsatira, kapena zotsutsana zomwe zimagwirizanitsidwa ndi mankhwala osokoneza bongo, kaya atumizidwa kapena kugula pa tsamba.
Mphamvu za Mucolytics mu COPD
Ngakhale kuti anthu ambiri akugwiritsa ntchito mankhwala osokoneza bongo mu COPD, umboni weniweniwo suwathandiza kwambiri.
Kuwonanso kwa mayesero okwana 34 ku 2015 kunatsimikizira kuti iwo omwe adatenga mucolytics sankakhala ndi zovuta zambiri za COPD . Pofufuza zotsatira, izi zidasintha pang'ono kuchepa kwa kuwonjezereka kwa zaka zitatu zilizonse. Maphunziro ena ali ndi zovuta zofanana.
Komabe, ngakhale pali zolephera izi, ena akhala akutsutsa kuti anthu ophatikizana ali ndi malo mu chithandizo cha COPD. Chifukwa cha nkhawa zokhudzana ndi ntchito yogwiritsira ntchito corticosteroid , pakhala pali malingaliro omwe angakhale oyenerera pa COPD yapamwamba momwe chiopsezo cha kuchulukitsira ndi chochuluka mosasamala za ntchito ya steroid.
Mucolytics, panthawiyi, angathandize kuchepetsa kuchuluka kwa kuchulukirapo ndi kupititsa patsogolo ubwino wa moyo.
Mmodzi wogwirizanitsa ndi Bronchitis Randomzed on Study NAC Cost-Utility Study (BRONCUS) ananenanso kuti, pamene agwiritsidwa ntchito ndi corticosteroid yosakanizidwa, mankhwala osokoneza bongo angachepetse kuchuluka kwa COPD ndi pafupifupi 21 peresenti.
Mucolytics ingathandizenso anthu omwe sali ovomerezeka ndi corticosteroids kapena ovutika ndi inhalers.
Zotsatira:
> Njira Yoyamba Yopeweratu Matenda Opatsirana. (2017) Guide Pocket kwa COPD Kusanthula, Kulamulira, ndi Kuteteza: Buku lothandizira odwala Health Care (Report 2017) .
> Loukides, S .; Bakakos, P .; ndi Kostikas, K. "Mucolytics mu COPD: Monga vinyo wofiira?" PNEUMON. 2013; 4 (26): 1-4.
> Poole, P .; Chong, J ;; ndi Cates, J. "Mucolytic wothandizira ndi malo omwe amatha kupwetekedwa matenda aakulu kapena matenda osokoneza bongo." Cochrane Database Syst Rev. 2015; 29: 7: CD001287.