Kuwonongeka kwa ubongo kungapangitse kugona mofulumira
Chizindikiro chimodzi choyamba chomwe chingasonyeze kuti vuto la ubongo, monga dementia , ndilo kusokoneza machitidwe ogona. Chifukwa chiyani odwala matenda a maganizo alibe tulo? Phunzirani mmene kusintha kwa ubongo kungakhudzire mapulumukidwe a kugona chifukwa cha kuwonongeka kwa nyumba zofunikira komanso momwe zikhalidwe zomwe zilili m'zinthu zamoyo zowonjezera zingawononge zotsatirazi.
Kusintha kwa ubongo kumakhudza kugona mu Dementia
Chinthu cha suprachiasmatic (SCN) mu hypothalamus ya ubongo ndi udindo wolamulira machitidwe athu ogona.
Izi nthawi zambiri zimatchedwa kuti circadian rhythm chifukwa zizoloŵezizi zimakhala zikupitirira nthawi yamasiku ano.
Ndi mitundu yambiri ya matenda osokoneza bongo - kuphatikizapo matenda ovutika maganizo monga matenda a Alzheimers , komanso mavuto a kayendedwe monga matenda a Parkinson - mbali zina za ubongo zingawonongeke pakapita nthawi. Maselo a ubongo (neurons) angakhale osamvera kwambiri mankhwala omwe amatchedwa neurotransmitters, kapena zinyalala zingayambe kusokoneza ntchito yawo. Kutentha kwa ubongo padziko lonse, wotchedwa atrophy, kumachitika ngati munthu wina wa neuroni amafa. Komanso, zigawo zina za ubongo zingatayike.
Ngati SCN yatayika, tidzakhala ndi mwayi wokhala ndi chizolowezi chogona tulo. Izi zikhoza kuwonetsa mu zovuta zosiyanasiyana za circadian zizindikiro . Kawirikawiri, okalamba adzakhala ndi matenda apakati ogona . Izi zimaphatikizapo chikhumbo chogona ndi kudzuka m'mawa kwambiri. Izi zimafuna kusintha ndondomeko zawo za kugona zikhoza kukhala zosatheka kuzilamulira ndipo zingayimire kusintha kwa ubongo monga zaka.
Sundowning ndi Zopweteka za Kugona Kosokonezeka kwa Osamalira
Kuonjezera apo, anthu ambiri omwe ali ndi vuto lodzidzimutsa, monga momwe amapezera m'maganizo, akhoza kuti asokoneza kugona. Amatha kupeza chilakolako chawo chogona usiku, pamene akugona madzulo. Nthawi zina okondedwa akhoza kukayikira kuti ali ndi matenda a 'dementia' pamene munthu ayamba kuchita ntchito zachilendo usiku, monga kutseketsa pakhomo pa 3 koloko kapena ntchito zina.
Kugonana kosasinthasintha kawirikawiri kumasonyeza nthawi zosachepera zitatu kugona mu maola 24, ndipo kugona tulo usiku kumakhala kuchepetsedwa.
Chochitika cha sundowning, chomwe munthu ali ndi chifuwa chachikulu chaumtima chimasokonezeka kwambiri ndikugwedezeka usiku, angayimire vuto la circadian. Makhalidwe amenewa athandizidwa bwino ndi melatonin, yomwe ingakhale nthawi yowonjezera.
Kawirikawiri odwala odwala matenda a maganizo amakhala osasokonezeka kwambiri ngati amasungidwa pamalo odziwika bwino, monga nyumba ya moyo wonse, m'malo mwa chipatala kapena malo okalamba. Kuwonjezera pamenepo, kugwiritsa ntchito chizoloŵezi kungapangitse kukumbukira kwawo ndi makhalidwe awo ndikupindula bwino. Zingakhalenso zotheka kuti sundowning ikuimira zosungirako zofooka; ndiko kuti, pamapeto a tsikulo munthuyo alibe mphamvu zowonjezera kuti akhalebe maso pazochita zawo ndi kuganiza. Zotsatira zake, zimakhala kapena zimawoneka zosokonezeka.
Kusintha Kwogona Kungakhale Chizindikiro Chakumayambiriro kwa Dementia
Kusokonezeka kugona kungakhalenso chizindikiro choyamba cha matenda omwe angakhalepo patapita nthawi. Mwachitsanzo, kafukufuku akusonyeza kuti khalidwe la msangamsanga la maso (REM) lagona ndi vuto la kugona lingayambitse chitukuko cha matenda a Parkinson kapena Lewy matenda a maganizo a m'mimba zaka zambiri izi zisanachitike.
Ndikofunika kuzindikira kuti matenda ambiri a mitsempha ali ndi zigawo za kusokonezeka kwa tulo, monga momwe zotsatira zingakhudzire dera la ubongo lomwe liri ndi udindo wotsogolera kugona kwathu. Izi zingapangitse kusokonezeka kwa zochitikazi, ndipo kusiyana pakati pa zizindikiro za circadian kungakhale chizindikiro choyamba kuti chinachake chiri choipa. Mwa kukhala osamala kwambiri ndi kusintha kumeneku, tikhoza kupeza chithandizo cham'tsogolo kwa omwe akusowa thandizo.
Kwa omwe akudwala matenda a maganizo, pangakhale kusintha kochepa kothandiza. Ndikofunika kuti nthawi zonse muzigona mokwanira. Kutuluka kwa m'mawa ndikofunikira kwambiri, ndipo kuwala masana ndi mdima usiku kumathandiza kulimbikitsa kugona.
Kudumphira kuyenera kuchepetsedwa masana kuti konzekere kugona usiku. Mankhwala otsika a melatonin angakhale othandiza ena. Mankhwala ena ogwiritsira ntchito mankhwala osokoneza bongo ayenera kuchepetsedwa chifukwa cha kuopsa kwa chisokonezo, kusungidwa kwa mitsempha, ndi kugwa. Ngati kugona kwapuloa kulipo, ayenera kuchiritsidwa kuti kuchepetse zotsatira za nthawi yaitali pamtima.
Ngati mukusowa thandizo, pitani kwa dokotala wanu wa banja ndipo muwone ngati mutumizidwa ku katswiri wa kugona ngati mukufunikira.
> Zotsatira:
> Bachman, D. et al . "Kusokonezeka ndi kusokonezeka kwa nthawi yochepa kumatenda odwala matenda a maganizo." Kupenda Kwadongosolo kwa Mankhwala. 57: 499-511, 2006.
> Deschenes, CL et al . "Zochiritso zamakono zowonongeka kugona kwa anthu omwe ali ndi matenda a maganizo." Malipoti Amakono Akumasulira. 11 (1): 20-6, 2009 Feb.
> Dowling, GA ndi al . "Melatonin ndi mankhwala owala kwambiri chifukwa cha kusokoneza ntchito kwa anthu odwala matenda a Alzheimer." Journal ya American Geriatrics Society. 56 (2): 239-46, 2008 Feb.
> Gehrman, PR ndi al . "Melatonin imalephera kukonza tulo kapena kusokonezeka m'mayesero awiri omwe amachititsa kuti anthu azikhala ndi matenda a Alzheimer." American Journal of Geriatric Psychiatry. 17 (2): 166-9, 2009 Feb.
> Hickman, SE ndi al . "Zotsatira za mankhwala othandizira kwambiri pa zizindikiro zachisoni kwa anthu omwe ali ndi matenda a maganizo." Journal ya American Geriatrics Society. 55 (11): 1817-24, 2007 Nov.
> Riemersma-van der Lek, RF ndi al . "Kuwunika kwa kuwala ndi melatonin pa ntchito yachidziwitso ndi yosadziwika kwa anthu okalamba m'mabungwe osamalirira magulu: kuyesedwa kosagwiritsidwa ntchito mosavuta." JAMA. 299 (22): 2642-55, 2008 Jun 11.
> Shub, D. ndi al . "Osagwiritsa ntchito mankhwala osokoneza bongo chifukwa cha kusowa tulo kwa anthu omwe ali ndi matenda a maganizo." Zojambulajambula . 64 (2): 22-6, 2009 Feb.