Topiramate Thandizo Lodyera Kugona, Kukhudzidwa, ndi Kutaya Kwambiri
Topamax ndi mankhwala a mankhwala omwe amagulitsidwa pansi pa dzina lachilendo topiramate. Ngakhale kuti kawirikawiri amauzidwa kuti asamalidwe ndi kupeweratu mutu wa mutu wa migraine , imagwiritsidwanso ntchito pochizira kugona . Zikuwoneka ngati zothandizira kulemera. Kodi Topamax amagwira ntchito bwanji komanso zotsatira zake zimakhala zotani?
Ntchito
Matenda otchedwa supamax angapangidwe kuti awononge matenda okhudzana ndi kugona (SRED).
Zingakuthandizenso kuchepetsa zozizwitsa kudya zigawo zomwe zimachokera ku tulo. Amagwiritsidwa ntchito kawirikawiri pochiza matenda omwe amapezeka ngati gawo la khunyu. Zapezeka kuti zothandiza kupewa mutu wa mutu wa migraine kuti ubwerere mobwerezabwereza ndipo ungatengedwe monga prophylaxis. Monga momwe zimayambitsira kulemera kwa thupi ngati mbali, zimagwiritsidwanso ntchito pazinthu izi.
Momwe Topamax Imagwirira Ntchito
Zenizeni zenizeni zowonetsera momwe Topamax ntchito siidziwika. Zimatsegula njira za sodium mu thupi lomwe limatseguka ndi kutseka poyankha makanema omwe amachitidwa mankhwala. Zimathandizanso ntchito ya mankhwala, kapena neurotransmitter, yotchedwa GABA. Kuphatikiza apo, imasokoneza mapulogalamu othandizira maselo a mankhwala otchedwa glutamate. Amalepheretsanso enzyme yotchedwa carbonic anhydrase.
Ndani Sagwiritse Ntchito Topamax?
Topamax sayenera kugwiritsidwa ntchito ngati muli ndi pakati. Chenjezo limalangizidwa ngati mukuyamwitsa.
Zingakhale zosagwiritsire ntchito mankhwala abwino ngati muli ndi vuto la chiwindi, impso, kapena mapapu. Sitiyenera kugwiritsidwa ntchito ndi mowa kapena mankhwala ena omwe amachititsa kuti mitsempha yambiri isokonezeke (makamaka zomwe zingakhudze ubongo). Anthu obadwa ndi matenda enaake okhudzana ndi matendawa sayenera kugwiritsa ntchito Topamax.
Ngati muli ndi mbiri yakuvutika maganizo, makamaka ndi maganizo odzipha, kapena mbiri ya impso miyala (yotchedwa nephrolithiasis), iyenera kugwiritsidwa ntchito mosamala. Chenjezo limalangizidwanso ngati muli ndi mavitamini otsika m'magazi (hypokalemia) kapena mavitamini a asidi, makamaka ngati gawo la kutsegula m'mimba kapena kutaya madzi m'thupi.
Mankhwalawa sangakhale oyenera kwa iwo amene ali ndi khunyu amene amachizidwa ndi zakudya zamakoteni komanso ali ndi matenda a khunyu. Chenjezo lotsatiridwa limalangizidwa pakukhazikitsa opaleshoni.
Zotsatira Zogwirizana
Monga momwe zingagwiritsire ntchito mankhwala aliwonse a mankhwala, pali chiopsezo cha zotsatirapo pogwiritsira ntchito Topamax. Ngakhale kuti anthu ambiri sakhala ndi zotsatirapo zambiri kapena izi, zina zomwe zingachitike ndi izi:
- Kuchepetsera kuganiza (kutsogolera pa dzina lakutcha "Dope-max")
- Kutopa kapena kugona
- Kusagona
- Chikhalidwe chimasintha (kuvutika maganizo, mantha, kapena nkhawa)
- Chizungulire kapena kusakhazikika (ataxia)
- Masomphenya amasintha (kuphatikizapo nystagmus ndi masomphenya awiri)
- Kutaya thupi, kulawa kusintha, kapena kusowa kwa njala (anorexia)
- Kutaya tsitsi (alopecia)
- Nsea, kupwetekedwa m'mimba, ululu wamimba, kapena kutsekula m'mimba
- Kuchepetsa kapena kusinthika kumva kapena kugwedeza (paresthesia)
- Kudandaula
- Kufooka
- Fever
- Matenda monga matenda a mkodzo (UTI) kapena sinusitis
- Mavitamini acidosis
Zochitika Zotheka Kwambiri
Palinso zotsatira zoopsa zomwe zingachitike pogwiritsa ntchito Topamax. Zochitika zazikulu izi zimachitika mochuluka kwambiri. Pogwiritsira ntchito Topamax, zina mwa zotsatira zake zingakhalepo:
- Matenda ofanana kwambiri a acidosis
- Miyendo ya impso (nephrolithiasis)
- Kuthamanga kwa mafupa kumasintha (osteomalacia kapena matenda otupa mafupa)
- Kuchepetsa thukuta (oligohidrosis)
- Kutentha kwa thupi kutentha (hyperthermia)
- Mavuto a potaziyamu (hypokalemia)
- Matenda a hyperammonemic (amasonyeza ngati chisokonezo)
- Kusinkhasinkha kapena kudzipha
- Chiwerengero cha maselo a magazi chimasintha (leukopenia kapena kuchepa kwa magazi)
- Mavuto a masomphenya kuphatikizapo glaucoma, acute myopia, kapena maculopathy
- Zomwe zimachititsa khungu monga matenda a Stevens-Johnson, poizoni epidermal necrolysis, ndi erythema multiforme
- Kuchulukitsa kukula (mwa ana)
- Mphuno kapena chilakolako chakumuna (ngati chimagwiritsidwa ntchito ndi amayi apakati m'zaka zitatu zoyambirira)
- Kuchotsa matendawa ndi kutaya mwadzidzidzi
Kusamala ndi Kuwunika
Monga tafotokozera mwatsatanetsatane, pali anthu ena omwe sayenera kugwiritsa ntchito Topamax kapena amene ayenera kuchigwiritsa ntchito mosamala. Topamax imafuna kuyesera kwa magazi, ndi creatinine ndi bicarbonate yowunika pazowonjezera ndiyeno nthawi ndi nthawi.
Mankhwalawa akhoza kuthandizana ndi mankhwala ena, ndipo mankhwala anu onse ayenera kuwerengedweratu ndi dokotala ndi wamankhwala kuti musapewe mavuto. Kuwonjezera pamenepo, ndikofunika kuzindikira kuvutika maganizo, kusintha kwa khalidwe, ndi malingaliro aliwonse odzipha monga momwe izi zingafunikire kusiya kumwa mankhwala.
Chifukwa cha chiopsezo cha kugwidwa, mankhwala sayenera kuimitsidwa mwadzidzidzi popanda kufunsa ndi dokotala wanu.
Ngati mukukumana ndi mavuto alionse pogwiritsa ntchito Topamax, muyenera kukhala pafupi kwambiri ndi chithandizo choyamba chaumoyo wanu.
Chitsime:
"Topamax." Epocrates Rx Pro . Version 16.10, 2016. Epocrates, Inc. San Mateo, California.