Kugwirizana pakati pa matumbo anu ndi migraines
Matenda owopsa a m'mimba (IBS) ndi migraines ndi matenda awiri osiyana ndi ululu, komabe iwo amakhala nawo mbali zina. Izi zikusonyeza kuti pali nthambi zomwe zimapezeka ngati zimayambira pamtundu wofanana.
Ndimodziwika kuti anthu omwe ali ndi IBS amakhala ndi migraines komanso mosiyana. Kaŵirikaŵiri anthu amadziŵa zambiri ndi matenda amodzi, kawirikawiri omwe amakhala opweteka kwambiri kapena opweteka.
IBS ndi Migraines monga Syndromes Pakati pa Chisamaliro
Akatswiri ambiri amasonyeza kuti migraines komanso matenda opwetekedwa ndi matumbo ndizopangitsa kuti thupi liziyenda bwino.
"Pakati" amatanthauza ululu umene umabwera chifukwa cha kusintha pakati pa mitsempha yamkati, yomwe ili ndi ubongo komanso msana.
"Chisamaliro" chimatanthauza kuti anthu omwe ali ndi migraines ndi IBS ali ndi mphamvu zowonjezera zomwe siziyenera kukhumudwitsa, zomwe zimatanthauza kuti amamva kupweteka kwambiri kusiyana ndi zachibadwa ndi nthenda ya singano ( hyperlagesia ) kapena ngakhale kusagwira nthawi zonse ( kuvomereza ).
Chisamaliro cha pakati pa Migraines
Panthawi ya migraine, asayansi amakhulupirira kuti mitsempha ya m'mphepete mwa ubongo imatha. Izi zimapangitsa kuti mitsempha yambiri ikhale yotsekemera (monga mitsempha yambiri ) kuti amasule peptide monga peptide yodzitetezera ya mtundu wa calcitonin (CGRP) , yomwe imalimbikitsa kutupa ndi kutumiza chizindikiro cha ubongo ku ubongo. Izi zimatchedwa kuti trigeminovascular pathway.
Potsirizira pake, ubongo umalimbikitsidwa kwa opangitsa, kutanthauza maselo a ubongo mu ubongo amatha kufalitsa mauthenga mosavuta kudzera mu njira yopweteka ya trigeminovascular chifukwa achita kale. Izi zimatchedwa kupititsa patsogolo pakatikati ndipo zingayambitse kupweteka kwa migraine kuti zikhale zovuta mosavuta ndi kuwonetsa komweko.
Chisamaliro chapakati ku IBS
Chodziwika bwino cha IBS ndi hypcerensitivity (visceral hypersensitivity), kutanthauza kuti ziwalo za munthu (mwachitsanzo, m'matumbo, m'mimba, chikhodzodzo) zimapangitsa kuwonjezeka kwa ululu. Ichi ndichifukwa chake kupweteka kwa mimba m'mimba kapena kusuntha kwa munthu kumakhala kovuta komanso kumayambitsa munthu yemwe ali ndi IBS.
Akatswiri amakhulupirira kuti visceral hypersensitivity ya IBS pamapeto pake imachititsa kuti mukhale ndi mphamvu m'katikatikati mwa manjenje. Izi zikhoza kufotokoza chifukwa chake anthu ambiri omwe ali ndi IBS amavutika ndi zowawa zowonjezereka (mwachitsanzo, migraines, mgwirizano, ndi kupweteka kwa minofu) ndipo ena samatero.
Zina Zofunika Kwambiri Kuzindikira Maganizo
Matenda ena omwe nthawi zambiri amawaika ngati syndromes pakatikati amatenga:
- fibromyalgia
- matenda aakulu
- ululu wopweteka kwambiri
- zamkati cystitis
Mofanana ndi matenda enawa, IBS ndi migraines zimapezeka ndi zizindikiro zawo, kutanthauza kuti palibe labata kapena mayesero owonetsera. M'malo mwake pali njira zomwe madokotala amagwiritsa ntchito kuti adziwe ngati wodwala amatha kutero-mndandanda wa zizindikiro zazitsulo, koma pang'ono.
The Estrogen Link: IBS ndi Migraines
Kuwonjezera pa kumvetsetsa kwapakati, onse a IBS ndi migraines amapezeka kwambiri mwa amayi. Izi zikusonyeza kuti mahomoni ogonana, makamaka estrogen, amachititsa mavutowa.
IBS ndi Estrogen
Mu IBS, estrogen imangosokoneza ululu komanso kupweteka kwa ubongo mu ubongo, komanso zimakhudza mphamvu ya m'matumbo anu, ululu wa m'matumbo anu, komanso mtundu wa mabakiteriya omwe amakula mumatumbo anu.
Izi zikunenedwa, udindo wa estrogen mu IBS ndi wovuta. Ichi ndi chifukwa chake maphunziro akutsutsana ndi momwe magawo ena okhudzidwa ndi mahomoni mu moyo wa mkazi amathandizira kapena kuwononga zizindikiro zake za IBS. Mwachitsanzo, kafukufuku amasonyeza kuti chiwerengero cha IBS n'chochepa pambuyo pa kuchepa kwa thupi , pamene maimidwe a estrogen m'thupi ndi otsika kwambiri. Izi zikunenedwa kuti amayi ena amanena kuti zizindikiro za GI zimawonjezereka, makamaka kudzimbidwa ndi kubwezeretsa, pambuyo pa kutha kwa thupi.
Migraines ndi Estrogen
Mu migraines, akazi amatha kusintha m'magraines awo pawiri ndi itatu ya mimba pamene mimba yawo yayitali. Chimodzimodzinso, kusamba kwa migraine kumakhala kofala m'mabambo azimayi ndipo amakhulupirira kuti akuyambitsidwa ndi dontho la estrogen, lomwe limangoyamba kumene.
Momwemonso, amayi ambiri amatha kukhala ndi migraine kwambiri pamene akuyandikira kusamba, pamene ntchito yawo yoyamba yowamba imayamba kuchepa ndi ma level estrogen m'thupi limayamba kugwa. Izi zikunenedwa kuti, migraine yawo ikuwoneka ngati ikupita pambuyo pa kutha kwa thupi-chithunzi china chophwanya, kutanthauza zinthu zingapo zomwe zikusewera.
Zochitika Zina Zofanana za IBS ndi Migraines
Zowononga matenda okhudza matenda a maganizo monga kupsinjika maganizo, nkhawa, ndi / kapena kupsinjika maganizo kwa matenda osokonezeka kuti agwirizane ndi IBS ndi migraines. Kukhala ndi matenda opatsirana m'maganizo kuphatikizapo matenda opweteka ndi zovuta kwambiri zomwe zimayambitsa china. Kawirikawiri zimakhala zovuta kudziwa chomwe chinafika poyamba, chiphunzitso cha "nkhuku ndi mazira". Ziribe kanthu, kuphatikiza kwa ululu wa thupi limodzi ndi kusokonezeka maganizo kumatha kuwononga moyo wa munthu ndi kugwira ntchito tsiku ndi tsiku.
Kuonjezera apo, sayansi tsopano ikuwonekera kuti anthu omwe ali ndi IBS ndi migraines akhoza kugawaniza majini wamba, makamaka omwe ali okhudzana ndi serotonin. Izi zimagwirizanitsa chifukwa zingathandize asayansi kulenga chithandizo chochiritsidwa kwambiri kwa IBS ndi migraines.
Kuchiza IBS ndi Migraines Yanu
Pofuna kuthetsa mavuto onsewa, madokotala amalimbikitsa mankhwala osiyanasiyana kuphatikizapo mankhwala ndi mankhwala, monga biofeedback kapena chidziwitso. Kuonjezera apo, mankhwala othandizira, monga machiritso , amagwiritsidwa ntchito ndi odwala kuti awonjezere kupweteka kwawo.
Asayansi akuyang'ananso njira zochiritsira zokha zomwe zingathandize mkhalidwe wonsewo, imodzi yokhala ndi mankhwala. Mu phunziro limodzi laling'ono la 2013 mu mutu, onse omwe ali ndi migraines ndi IBS amadya zakudya, chifukwa cha mavitamini apamwamba m'magazi awo akamadya zakudya zina. IgG ndi antibody ndi chizindikiro cha kutupa thupi. Zakudyazo zinachepetsa zizindikiro zonse za IBS ndi migraines mwa ophunzirawo.
Pansi
Kugwirizana pakati pa matenda awiri sikukutanthauza kuti wina amachititsa china, kapena kuti pokhala ndi njira imodzi mumatha kukonza zina. Zimangotanthauza kuti pali chiyanjano.
Kuphunzira kugwirizana pakati pa IBS ndi migraines kumathandiza asayansi kumvetsa bwino chifukwa chake mavutowa amakula ndi momwe madokotala angawachitire bwino-njira yochepetseka yomwe imafuna kutanthauzira komanso kuphunzira mozama.
Zotsatira:
Aydinlar El et al. Zakudya Zowonongeka KwagGineka mu Migraine Plus Irritable Bowel Syndrome. Mutu . 2013; 53 (3): 514-25.
Chang FY, Lu CL. Irritable Bowel Syndrome ndi Migraine: Oimirira kapena Othandizira? J Neurogastroenterol Motil. 2013; 19 (3): 301-11.
Moshiree B, Zhou Q, Price DD, Verne GN. Chisamaliro cha Pakati pa Matenda Osautsa. Kutha . 2006; 55 (7): 905-8.
Mulak A, Taché Y, Larauche M. Sex Hormones pa Kusinthika kwa Irritable Bowel Syndrome. World J Gastroenterol . 2014; 20 (10): 2433-48.
Uluduz D et al. Kugwirizana pakati pa Migraine, Kuthamanga Mutu Mutu wa M'mutu ndi Irritable Bowel Syndrome: Zizindikiro Zamakono ndi Zachilengedwe. Neurology . 2016; 86 (16) SupplementP4.120.