Hippocampus ndi dera la ubongo pansi pa lobes yamkati. Chimodzimodzinso ndi mawonekedwe a nyanja, ndipo pali mbali imodzi ya ubongo pamwamba pa makutu.
Zimene Iwo Amachita
Hippocampus imatithandiza kukumbukira zinthu zatsopano. Nthaŵi zina amawoneka ngati njira yopita kukumbukira ngati kuti kukumbukira kukufunika kudutsa mu hippocampus kuti ikhale yosungidwa mu banki ya nthawi yaitali .
Kafukufuku wina wasonyeza kuti hippocampus ndi yofunikira osati kungopanga zochitika zatsopano komanso kuchotsa kukumbukira zakale.
Chochititsa chidwi, kuti hippocampus kumbali ya kumanzere nthawi zambiri imakhala ndi ntchito yaikulu mu chikumbukiro ndi chinenero kuposa momwe ili kumanja.
Mmene Matenda a Alzheimer Amakhudzira Hippocampus
Kafukufuku wapeza kuti mbali imodzi yoyamba mu ubongo yomwe imakhudzidwa ndi matenda a Alzheimer ndi hippocampus. Asayansi agwirizanitsa atrophy (shrinkage) m'madera a hippocampal ndi kukhalapo kwa matenda a Alzheimer's. Atrophy m'dera lino la ubongo amathandiza kufotokoza chifukwa chimodzi mwa zizindikiro zoyambirira za matenda a Alzheimer's nthawi zambiri zimakhala zosavuta kukumbukira, makamaka kupanga mapangidwe atsopano.
Hippocampus atrophy inagwirizananso ndi kupezeka kwa mapuloteni omwe amamanga ngati matenda a Alzheimers akupitirira.
Kulephera Kuzindikira Maganizo
Choncho, kukula ndi kukula kwa hippocampus kumakhudzidwa kwambiri ndi matenda a Alzheimers.
Koma nanga bwanji mu kufooka kofatsa, zomwe nthawi zina, koma nthawi zonse, zimapita ku matenda a Alzheimer's?
Kafukufuku wasonyeza kuti atrophy ya hippocampus imagwirizananso ndi kukhumudwa pang'ono . Ndipotu kukula kwa hippocampus ndi mlingo wa shrinkage kwawonetsedwa ngati MCI ikupita ku matenda a Alzheimer kapena ayi.
Vuto laling'ono la hippocampal ndi liwiro lachangu kapena lachangu lomwe likugwirizana ndi chitukuko cha maganizo.
Kodi Hippocampal Volume ingasiyanitse pakati pa mitundu yosiyanasiyana ya Dementia?
Kafukufuku wochulukitsa kafukufuku wayeza chiwerengero cha hippocampal ndikuyang'ana momwe ikukhudzana ndi mitundu ina ya malingaliro. Chotheka chinali chakuti madokotala akhoza kugwiritsa ntchito kuchuluka kwa atrophy mu dera la hippocampal kuti adziwe bwino lomwe mtundu wa chifuwa cha dementia.
Mwachitsanzo, ngati matenda a Alzheimer ndiwo okhawo omwe ali ndi matenda a dementia omwe amakhudza kwambiri kukula kwake kwa hippocampus, izi zingagwiritsidwe ntchito pozindikira kuti Alzheimer's. Komabe, kafukufuku wambiri wasonyeza kuti muyeso uwu nthawi zambiri siwothandiza kusiyanitsa mitundu yonse ya matenda a maganizo.
Kafukufuku wina wofalitsidwa m'nyuzipepala yotchedwa Neurodegenerative Diseases adanena kuti kuchepa kwa hippocampus kunachitika m'mutu waukulu wa dementia .
Kafukufuku wachiwiri anapeza kuti kuchepa kwa chiwembu cha hippocampal kunalumikizananso ndi frontotemporal dementia .
Asayansi adapeza kusiyana kwakukulu, komabe poyerekeza ndi Lewy thupi la Dementia ndi matenda a Alzheimer's. Lewy thupi la dementia limasonyeza kuchepa kwa atrophy kumadera a hippocampal mu ubongo, zomwe zimagwirizananso ndi zotsatira zochepa pa kukumbukira, makamaka m'mayambiriro a matenda a maganizo a Lewy .
Kodi Mungathe Kuteteza Hippocampus Yanu Kuti Ichepe?
Pulasitiki (mawu oti ubongo amatha kukula ndikusintha nthawi) ya hippocampus yawonetsedwa mobwerezabwereza mufukufuku. Kafukufuku wapeza kuti, ngakhale kuti hippocampus imafika potiyesa pamene tikulamba, kuchita masewera olimbitsa thupi ndi kusonkhezeretsa maganizo (kuchepetsa maganizo) kungachepetse kusokoneza, ndipo nthawi zina kumayambiranso.
Zotsatira:
Clinical Cleveland. Lobe Wam'nyengo. http://my.clevelandclinic.org/anatomy/brain/ns_overview.aspx
Dementia ndi Matenda Odzidzidzidwa Odzidzimutsa. 2010; 29: 294-300. Kuphatikiza kwa Hippocampal Volume ndi Cerebrospinal Fluid Biomarkers Zimapangitsa Phindu Loyamba mu Kulephera Kwachidziwitso Chochepa. http://www.karger.com/Article/Abstract/289814
Dementia ndi Matenda Odzidzidzidwa Odzidzimutsa. 2012; 34 (1): 44-50. Kuyerekezera hippocampal atrophy mu matenda a Alzheimer's and dementia ndi matupi okhwima. http://www.ncbi.nlm.nih.gov/pubmed/22922563
Journal of Disease's Alzheimer's. 2013 Jan 1; 36 (1): 57-66. onetsani: 10.3233 / JAD-122293. Kodi chiwerengero cha hippocampal ndi chizindikiro chabwino chosiyanitsa matenda a Alzheimer ku matenda a dementia? http://www.ncbi.nlm.nih.gov/pubmed/23542864
Kutaya kwa Memory ndi Ubongo. Hippocampus. http://www.memorylossonline.com/glossary/hippocampus.html
Zofufuza za Chilengedwe Neurology 8, 189-202 (April 2012). Zinthu zosinthika zomwe zimasintha kukula kwa hippocampus ndi kukalamba.
Matenda a Neurodegenerative. 2011; 8: 465-469. Hippocampal Atrophy mu Subcortical Vascular Dementia. http://www.karger.com/Article/FullText/326695
Neurology. March 17, 2009 vol. 72 ayi. 11 999-1007. Hippocampal atrophy rates mu matenda a Alzheimer. Kuwonjezeka kwowonjezera payeso yonse ya mphamvu ya ubongo. http://n.neurology.org/content/72/11/999