Ankylosing Spondylitis

Zachidule za Ankylosing Spondylitis

Ankylosing spondylitis ndi mtundu wa nyamakazi yomwe imakhala ndi kutupa kosatha kumene kumakhudza kumbuyo ndi khosi (ie, msana). Pa milandu yoopsa, mafupa omwe ali mumsana amatha kuponyera (amatchedwanso kuti ankylosis) omwe amachititsa kuti msana ukhale wolimba komanso wosagwedera. Zochitika zosalimba zingakhale zotsatira. Mankhwala ena angaphatikizepo mbali, kuphatikizapo m'chiuno, mawondo, mabotolo, kapena mapewa. Matendawa akhoza kugwiritsidwa ntchito ndi njira zowonongeka , kukhudza ziwalo zosiyanasiyana za thupi.

> Onani momwe spondylitis ankylosing, mtundu wa nyamakazi, imakhudza msana.

Ankylosing spondylitis ndi gulu la mikhalidwe yotchedwa spondyloarthropathies . Ma spondyloarthropathies ena ndi awa:

• Matenda a nyamakazi
• Psoriatic nyamakazi
• Matenda a nyamakazi ogwidwa ndi matenda otsekula m'mimba (ulcerative colitis kapena matenda a Crohn)
• Nyamakazi yotchedwa entopathic

Spondyloarthropathies amaikidwa ngati axial kapena peripheral, malingana ndi ziwalo zomwe zimakhudzidwa.

• Zimene Mukuyenera Kudziwa Zokhudza Kusanthula Ankylosing Spondylitis

• Kuchiza kwa Ankylosing Spondylitis

Axial imatanthauza kukhudza msana. Mphindi imatanthawuza ziwalo zina kunja kwa msana. Ankylosing spondylitis ndi axial spondyloarthropathy.

Chifukwa cha Ankylosing Spondylitis

Chifukwa cha matendawa sichikudziwika, koma galasi la HLA-B27 liripo 90 peresenti ya anthu omwe ali ndi matendawa, kutanthauza kugwirizana kwa chibadwa. Komabe, ndikofunika kuzindikira kuti si onse amene ali ndi jini la HLA-B27 limene limapanga ankylosing spondylitis. Malingana ndi Spondylitis Association of America, mwina pali majini asanu kapena asanu ndi limodzi omwe amawoneka kuti ali ndi kachilombo ka ankylosing spondylitis. Ochita kafukufuku amakhulupirira kuti chilengedwe chomwe chimachititsa kuti chilengedwecho chikhalepo pamodzi ndi chiwopsezo ndicho chimene chimayambitsa matendawa.

Ndani Amalandira Sponyylitis Ankylosing?

Chikhalidwe chimakhudza kwambiri amuna. Amuna awiri kapena atatu amodzi kuposa abambo amapanga matendawa. Komabe, aliyense akhoza kukhala ndi ankylosing spondylitis. Ukalamba umayamba nthawi zambiri pakati pa zaka 17 ndi 35. Malingana ndi CDC (Zopangira Zowononga Matenda ndi Chitetezo cha NHANES), akuluakulu oposa 2.7 miliyoni ku US ali ndi axial spondyloarthritis.

Zizindikiro Zogwirizana ndi Ankylosing Spondylitis

Zizindikiro zoyambirira za ankylosing spondylitis ndizopweteka ndi kuuma mu gawo lakumbuyo. Zizindikiro kawirikawiri zimayambira asanakwanitse zaka 45. Ululu ndi kuuma zimasintha ndikukhala zizindikiro zosatha. Kawirikawiri, kupweteka kwapondylitis kumapangitsa kuti kupumula kapena kusagwiritsidwa ntchito kukhale kosavuta komanso kumapangitsanso ntchito. Ikhoza kuyambitsa kuuma kwa m'mawa komwe kumatenga mphindi 30.

Ululu ndi kuuma, pakapita nthawi, zimatha kupita msana kupita m'khosi. Mafupa a msana ndi khosi angapangidwe, kupangitsa kuyenda pang'ono ndi kuchepa kwa msana.

Monga tanenera kale, mapewa, chiuno, ndi ziwalo zina zingakhale zogwirizana. Kupweteka kwa nju kumakhala kofala kwambiri ndi ankylosing spondylitis ndipo ikhoza kugwirizanitsidwa ndi ululu m'mphuno kapena matako, komanso kuyenda kovuta. Ngati nthiti ya nthiti ikuphatikizidwa, kufalikira kwachifuwa kosazolowereka kungayambitse kupuma. Tendons ndi mitsempha zimakhudzidwa (mwachitsanzo, chidendene chophatikizidwa ndi tendonitis Achilles ndi fasciitis ).

Ankylosing spondylitis ndi matenda a systemic, kutanthauza kuti anthu akhoza kukhala ndi malungo, kutopa, diso, kapena kutupa thupi. Kugwira mtima kwa mtima kapena m'mapapo sikusowa koma n'kotheka.

Kuzindikira kwa Ankylosing Spondylitis

Chidziwitsochi chimachokera ku zizindikiro, kuyesa thupi, kuyesa magazi, ndi kufufuza. Zizindikiro zoyambirira za ankylosing spondylitis zimatha kufanana ndi zizindikiro zina, kotero kuti mayesero amagwiritsidwa ntchito pofuna kutulutsa matenda ena a spondyloarthropathies ndi matenda ena a rheumatic . Kusowa kwa kachirombo ka chifuwa chachikulu ndi mitsempha yamatenda kumathandiza kusiyanitsa ndi nyamakazi ya nyamakazi .

Ngakhale kulibe magazi amodzi omwe angathe kutsimikiziridwa mosapita m'mbali kuti ankylosing spondylitis, mayeso a HLA-B27 amapereka chidziwitso chofunika kwambiri, makamaka m'magulu ena a anthu. Mwachitsanzo, ankylosing spondylitis ndizovuta kuyerekezera kwa munthu yemwe ali woyera, wochokera ku Ulaya, ndi woipa kwa HLA-B27. Mayesero a kutupa kwapadera ( kuchepa kwa dothi ndi CRP ) ndi othandiza popanga chithunzithunzi cha kuchipatala, koma sichikudziwitsani.

Maphunziro a kufotokoza zomwe zimasonyeza kusindikizidwa kwa ankylosing spondylitis m'magulu a sacroiliac . Ngakhale kuti kusinthako kumawoneka pa x-ray, zingatenge zaka zitatha kuyambira kwa zizindikiro kuti zionekere. MRI ingagwiritsiridwenso ntchito kuyang'ana kusintha kwa makhalidwe kumalumikiro a sacroiliac. Ma X-ray amagwiritsidwa ntchito pofufuza umboni wa kuwonongeka kwa msana.

Kuchiza kwa Ankylosing Spondylitis

Chithandizo cha matendawa chimayang'ana kuchepetsa kupweteka, kuuma, ndi kutupa. Kulepheretsa kuwonongeka, kusunga ntchito, ndi kuika maphunziro pazinthu ndizo zolinga zamankhwala.

• Kodi Axial Spondyloarthritis ndi Ankylosing Spondylitis Zimakhudzana Bwanji?

• Kodi Ndi Zizindikiro Ziti za Ankylosing Spondylitis?

Mankhwala ogwiritsira ntchito ankylosing spondylitis ndi awa:

• Mankhwala otsutsana ndi kutupa (NSAIDs) ndiwo mzere woyamba wa mankhwala opatsirana mankhwala. Anthu ambiri amagwiritsa ntchito mankhwala a NSAID okha kuti aziwongolera.
• Mankhwala opweteka kapena opweteka angagwiritsidwe ntchito ngati ululu sukuyendetsedwa bwino ndi NSAIDs okha.
• Nthenda ya TNF ( Humira (adalimumab) , Remicade (infliximab) , Enbrel (etanercept) , Cimzia (certolizumab pegol) , ndi Simponi (golimumab) amavomerezedwa kuti apange spondylitis ankylosing ndipo awonetsa kusintha kwakukulu kwa matenda.
• Costyx (secukinumab) , IL-17 inhibitor, inangobvomerezedwa mu January 2016 kuti izi zichitike.
• DMARD (matenda ogulira anti-rheumatic drugs) angagwiritsidwe ntchito kuchepetsa matenda. Kawirikawiri, sulfasalazine imagwiritsidwa ntchito pa odwala ankylosing spondylitis omwe ali ndi nyamakazi yowopsa yomwe sangagwiritse ntchito matope a TNF. Methotrexate yokha ingathandize anthu ena, koma kawirikawiri sikumagwira ntchito yothandiza ankylosing spondylitis. Wina DMARD, Arava (wotsala) , amawoneka ngati wopindula pang'ono kapena wopanda phindu.
• Mlomo wamakono corticosteroids sagwiritsidwa ntchito kawirikawiri, koma pamene atengedwa, ayenera kukhala yaifupi, osati nthawi yayitali.

Kuchiza thupi ndi kuchita masewero olimbitsa thupi ndi gawo lalikulu la dongosolo lililonse la mankhwala a ankylosing spondylitis. Kufunika kochita masewera olimbitsa thupi, monga mbali yothandizira matendawa ndi kusunga machitidwe ndi ntchito, sikungatheke.

Kugonjetsa kwa Ankylosing Spondylitis

Anthu ena omwe ali ndi matendawa amakhala ndi matenda ochepa ndipo amatha kugwira ntchito komanso kugwira ntchito bwinobwino. Ena amakhala ndi matenda aakulu ndipo amakhala ndi zovuta zambiri chifukwa cha matenda a axial. Anthu ena omwe ali ndi spondylitis ankylosing amakhala ndi mavuto oopsa omwe amawopseza moyo wawo-koma si choncho kwa ambiri.

Kawirikawiri, wodwala ali ndi vuto lochita masewera olimbitsa thupi lomwe ambiri amatha. Pafupifupi 1 peresenti ya anthu omwe ali ndi matendawa amakwaniritsa masewera omwe zizindikiro zimachepetsa ndipo iwo amawoneka kuti akukhululukidwa.

Samalani Izi

Mphepete yomwe yasokoneza, kapena yosasinthasintha, imakhala yotengeka kwambiri. Izi zikuti, muyenera kukumbukira zoopsa zomwe mungachite ndikusamala. Muyenera kuchepetsa kapena kupewa njira zilizonse zomwe zingapangitse ngozi yanu kugwa. Izi zingaphatikizepo chirichonse kuchotsa kuchuluka kwa mowa womwe umagwiritsa ntchito poika zitsulo ndikukweza makapu m'nyumba mwanu. Pewani ntchito yaikulu. Kwenikweni, gwiritsani ntchito luntha komanso chitetezeni msana wanu.

Muyenera kugwiritsa ntchito miyendo yomwe imayika khosi lanu ndikubwezeretsani bwino mukamagona kapena kugona. Nthawi zonse gwiritsani ntchito lamba wanu wamtendere pamene mukuyendetsa galimoto kapena ngati mukuyenda pagalimoto. Komanso, anthu omwe ali ndi spondylitis ankylosing omwe amasuta fodya akulangizidwa kusiya kuti athetse vuto lawo lopuma. Ndipo musaiwale kufunika kochita nawo pulogalamu yogwiritsira ntchito zolimbitsa thupi kuti mukhazikike msana komanso kuti mukhale ndi thanzi labwino.

Mawu Ochokera

Momwe mumakhalira ndi ankylosing spondylitis zimadalira kukula kwa matenda anu, komanso momwe mumakhalira kuti mupitirizebe kuntchito yanu, kuchita masewera olimbitsa thupi, komanso kuteteza msana wanu. wakupatsani inu mfundo zenizeni za mkhalidwewu ndipo ndi gwero lomwe mungathe kubwereranso kumalangizi othandizira matenda omwe mukufuna.

> Zotsatira:

> Ankylosing Spondylitis. Spondylitis Association of America. Inapezeka pa 07/16/2016.

> Spondyloarthritis. Clinical Cleveland. 11/04/2014.

> Van der Linden S et al. Ankylosing Spondylitis. Kelley's Textbook ya Rheumatology. Mutu 75. Elsevier. Kusindikiza kwachisanu ndi chinayi.

> Yu DT. Kufufuza ndi Chithandizo cha Ankylosing Spondylitis mwa Anthu Achikulire. Zaposachedwa. 04/21/2016.

> Yu DT. Information Patient: Ankylosing Spondylitis ndi Other Spondyloarthritis (Kupitirira Zowona). Zaposachedwa. Kusinthidwa 04/12/2016.