Psoriatic Arthritis

Chidule cha Psoriatic Arthritis

Matenda a Psoriatic ndi kutupa kwa nyamakazi yogwirizanitsa ndi psoriasis (chikhalidwe cha khungu) ndi zizindikiro zosakanikirana. Zizindikiro za kutupa kwa psoriasis ndi kuzigwirizanitsa nthawi zambiri zimakhala zosiyana. Pa 85 peresenti ya anthu omwe ali ndi matendawa, zizindikiro za psoriasis zimayambitsa zizindikiro za nyamakazi. Nyamakazi imayamba pamaso pa psoriasis mpaka 15 peresenti ya anthu okhala ndi nyamakazi ya psoriatic.

> Kuwona nyamakazi ya psoriatic pambali pa zala.

Malingana ndi CDC, anthu akuluakulu pafupifupi 6.7 miliyoni ku United States ali ndi psoriasis. Kwa anthu okhala ndi psoriasis, pafupifupi 15 peresenti amakhala ndi nyamakazi ya psoriatic. Kuwonekera kwake kwenikweni sikudziŵika, koma akuti pafupifupi pakati pa 0.3 peresenti ndi 1 peresenti ya anthu. Ukalamba wa nyamakazi ya psoriatic nthawi zambiri imakhala pakati pa zaka makumi atatu ndi makumi asanu ndi zitatu, koma ikhoza kumakula pa msinkhu uliwonse. Amuna ndi amai ali ndi zofanana.

• Zimene Mungadziwe Zokhudza Otezla (Apremilast)

• Stelara Ndi Mankhwala Osakaniza Mankhwala a Psoriasis ndi Psoriatic Arthritis

Zizindikiro Zogwirizana ndi Psoriatic Arthritis

Zizindikiro zokhudzana ndi matenda a psoriatic zimasiyana ndi momwe zimakhalira komanso zomwe zimakhudza ziwalo. Mgwirizano uliwonse m'thupi ungakhudzidwe ndi ululu ndi chifundo. Pakhoza kukhala kulimbika ndi zovuta kusuntha ziwalo zomwe zakhudzidwa mwa njira yawo yoyenera. Anthu ena omwe ali ndi matendawa amakumana ndi mavuto omwe amatha kukhala oposa theka la ora. Ngati psoriasis ikuphatikizidwa, pali ziboliboli za malo ofiira, otukuka, otukuka, kapena otupa. Zosalala za msomali zingawoneke ngati pitting ndi zowonjezera kapena zowonongeka zipilala. Zizindikiro zina zomwe zimagwirizanitsa ndi matenda a nyamakazi zimakhala monga kutopa, zala zofiira, ndi zala (dactylitis), tendinitis , enthesitis, kupweteka kwa msana , ndi conjunctivitis .

• Zizindikiro ndi Zizindikiro za Psoriatic Arthritis

Mitundu ya Psoriatic Arthritis

Matenda a Psoriatic ndi a gulu la zinthu zomwe zimadziwika kuti spondyloarthropathies . Pali mitundu isanu yodziwika ya nyamakazi ya psoriatic yomwe imasiyanitsidwa ndi zizindikiro zawo. Mitundu isanu, yomwe ingagwirane, ndi:

• Matenda a Psoriatic Arthritis amakhudza ziwalo kumbali zonse ziwiri za thupi (mwachitsanzo, mawondo onse awiri, m'chiuno), ndipo nthawi zambiri zimakhudza ziwalo zingapo (polyarthritis) . Chimodzimodzinso ndi nyamakazi ya nyamakazi koma nthawi zambiri imakhala yosauka kwambiri. Pafupifupi 25 peresenti ya odwala psoriatic nyamayi ali ndi matendawa.
• Psychothatic Arthritis Somweyi sichimakhudza ziwalo zomwezo kumbali zonse ziwiri za thupi. Mgwirizano uliwonse ukhoza kuthandizidwa, komabe. Kuwoneka-ngati mawonekedwe a zala ndi zala kumakhala kofala. Ziphuphu zingakhale zofiira, zotentha, zotupa, ndi zopweteka. Kawirikawiri amaganiziridwa ngati nyamakazi ya psoriatic nyamakazi, ikhoza kukhala yosokoneza mwa anthu ena. Pafupifupi 80 peresenti ya anthu omwe ali ndi nyamakazi ya psoriatic amakhudzidwa ndi matendawa.

• Psalist Arthritis (Distal Interphalangeal Predominant) (DIP) imaonedwa kuti ndi "mtundu wamakono," malinga ndi National Psoriasis Foundation, ngakhale kuti anthu pafupifupi 5 mpaka 10 peresenti ya amene ali ndi nyamakazi ya psoriatic. Mbali yaikulu ya nyamakazi yotchedwa psoriatic nyamakazi ndi kuloŵerera kwa mbali zosiyana za zala ndi zala (mgwirizano pafupi ndi msomali), komanso umboni wa kusintha kwa msomali.
• Spondylitis Mtundu wa Psoriatic Arthritis uli ndi kutupa kwa msana monga chizindikiro chachikulu. Pafupifupi 5 mpaka 20 peresenti ya anthu omwe ali ndi nyamakazi ya psoriatic amakhudzidwa ndi mtundu wa spondylitis. Pafupi theka la awo omwe ali ndi spondylitis ali ndi chitsimikizo cha HLA-B27 , chizindikiro cha chibadwa.
• Matenda a Arthritis Mutilans Mtundu wa Psoriatic Arthritis umaonedwa kuti ndi wovuta, wosasokoneza, komanso wosawoneka. Osachepera 5 peresenti ya anthu omwe ali ndi nyamakazi ya psoriatic amakhudzidwa. Kuwonongeka kofanana kumaphatikizapo nyamakazi ya mutilans ndi zigawo zing'onozing'ono za manja ndi mapazi omwe amakhudzidwa kwambiri. Kupweteka kwa mitsempha komanso kupweteka kwa m'mimba kumagwirizananso ndi nyamakazi imeneyi.

Kuzindikira kwa Psoriatic Arthritis

Palibe mayesero amodzi omwe amagwiritsidwa ntchito kuti apeze matenda a psoriatic nyamakazi. Kufufuza mwakuthupi, x-rays, ndi MRI amagwiritsidwa ntchito kuti athandizidwe. Mayesero a magazi amagwiritsidwa ntchito kuti athetse mitundu ina ya nyamakazi yomwe ili ndi zizindikiro zofanana, monga nyamakazi yamagazi, gout, nyamakazi yowonongeka , anthlosing spondylitis , ndi osteoarthritis .

Ngakhale kuti mbali zina za matenda a nyamakazi ndi ofanana ndi mitundu ina ya nyamakazi, khungu la khungu, misomali yokhomerera, ndi njira za kutupa zimasiyanitsa ndi matenda ena a kutupa nyamakazi. Ngati matendawa atatsimikiziridwa ndi dokotala, mankhwala oyenera akhoza kuyamba. Kufufuza koyambirira ndi kuchiritsidwa koyambirira n'kofunika kuti matendawa awonongeke, kupereka mwayi wabwino wopezera olemala, matenda opatsirana, ndi kuwonongeka kosatha.

• Kuyesedwa ndi Kuzindikira Matenda a Psoriatic Arthritis

Chithandizo cha Psoriatic Arthritis

Chifukwa chakuti nyamakazi ya psoriatic imaphatikizapo mawonetseredwe a khungu onse ndi mawonetseredwe ogwirizana, cholinga cha njira iliyonse yothandizira ayenera kukhala ndi cholinga chokhacho.

• Nthendayi: Njira Yothandizira Ankylosing Spondylitis ndi Psoriatic Arthritis

• Kusintha kwa Zakudya Kungathandize Kusamalira Psoriatic Arthritis

Katswiri wanu wamatenda adzawona kuopsa kwa matenda posankha chithandizo, komanso kuganizira zotsatira za mankhwala ena pa matenda ena. Mwachitsanzo, kodi mankhwala osankhidwa kuti athetse matenda a nyamakazi angathandize kapena kuvulaza khungu la nyamakazi? Kugonjetsedwa ndichinthu chofunikira pakusankha chithandizo.

Kawirikawiri, NSAIDs (mankhwala osokoneza bongo omwe si othandizirapo) ndi mankhwala a mzere woyamba kwa anthu omwe ali ndi zizindikiro za nyamakazi zochepa. Kwa anthu omwe ali ndi zizindikiro zochepa za amagazi, omwe samayankha bwino NSAIDs okha, DMARD (matenda osinthira anti-rheumatic drugs) , monga methotrexate kapena Arava (leflunomide) , angagwiritsidwe ntchito. Mankhwala osokoneza bongo , monga TNF blockers , ndi oyenera kwa anthu omwe ali ndi matenda aakulu (mwachitsanzo, umboni wa zowonongeka, ziwalo zingapo zakhudzidwa, kuchepa kwakukulu kwa ntchito ). Corticosteroids nthawi zambiri sagwiritsa ntchito psoriatic nyamakazi.

Pamene zizindikiro za khungu zimakhala zotchuka, mwinamwake mofanana kwambiri ngati zizindikiro zovomerezeka, mankhwala omwe angathe kulamulira onse ndi abwino kwambiri. Mankhwala a TNF amaonedwa kuti ndi othandiza pakhungu komanso palimodzi pamaganizo a nyamakazi. Methotrexate, photochemotherapy, PUVA, retinoic acid, ndi cyclosporine A akhoza kuthandizanso maonekedwe a khungu ndi mgwirizano.

Pali mankhwala atsopano omwe angapezeke ndi masamu a psoriatic omwe angaganizidwe, nawonso:

• Otezla (apremilast)
• Costyx (secukinumab)
• Stelara (ustekinumab)

Kugonjetsedwa ndi Matenda a Psoriatic Arthritis

N'zochititsa chidwi kuti panthaŵi ina, matenda a psoriatic anali kuganiza kuti ndi matenda ofatsa. Kwenikweni, nyamakazi ya psoriatic ndi yovuta kwambiri kusiyana ndi poyamba. Zovomerezana za sayansi zavumbula kuti, ponena za kuwonongeka kwa mgwirizano wopitirirabe, kufotokoza kosauka kumagwirizana ndi:

• Chiwerengero chapamwamba cha ziwalo ndi kutupa kokwanira
• Kuthamanga kwapamwamba kwa sedimentation ndi CRP
• Kuwonongeka kofanana kumayambira pa x-rays
• Kulephera kukwaniritsa yankho loyenera ndi mankhwala ena
• Zolephera kugwira ntchito
• Mkhalidwe wosauka wa moyo

Kuti mukhale ndi mphamvu pa matenda a psoriatic, ndi kofunika kuti muyesedwe, muyesetse, ndipo mukumuthandizidwa ndi rheumatologist . Anthu omwe ali ndi nyamakazi yapamwamba omwe amalandira chithandizo cham'mawa amakhala ndi mwayi wabwino wothetsera matenda ndi kuwonongeka kwa palimodzi. Zimadziwikanso kuti nyamakazi ya psoriatic imagwirizanitsidwa ndi comorbidities, chiopsezo chowonjezeka cha mavuto, ndi kuchuluka kwa kufa-chifukwa china chomwe kuchizira koyambirira n'kofunika.

• Mavuto a Psoriatic Arthritis

Kusamalira bwino nyamakazi ya psoriatic kumafuna kuti mukhale wogwirizana ndi ndondomeko yanu ya mankhwala, zolimbitsa thupi, kugwiritsa ntchito njira zothandizira palimodzi, kusunga ulemelero wanu, ndikuyang'anira comorbidities (mwachitsanzo, mtima wa mtima).

Mawu Ochokera

Matenda a Psoriatic amatchedwa nyamakazi yowopsya yothamanga chifukwa cha kugwirizana ndi psoriasis. Kuti, kuphatikizapo mavuto omwe angakhale nawo komanso zochitika zogwirizana ndi comorbid, zimakhala zofunikira kuti chithandizo chitheke chikufulumira. Cholinga cha anthu omwe ali ndi nyamakazi ya psoriatic ndi kuyendetsa bwino matendawa ndi kuchepetsa zotsatira zake pa moyo wawo. Pa, takufotokozerani zomwe mukufunikira kudziwa zokhudza matenda a psoriatic nyamakazi. Kudziwa kumeneku kudzakuthandizani kumvetsetsa malangizo a dokotala wanu, kupanga mafunso ofunsa dokotala wanu, ndi kulimbikitsidwa ndi njira zothandizira chithandizo, kuphatikizapo zina zomwe ziri zatsopano.

> Zotsatira:

> Gladman DD et al. Psoriatic Arthritis: matenda, matenda, njira, ndi zotsatira. Annals wa Rheumatic Disease. 2005; 64: ii14-ii17

> Gladman DD ndi Ritchlin C. Kuwonetseredwa kwachipatala ndi Kuzindikira kwa Maganizo a Maganizo. Zaposachedwa. Kusinthidwa 02/12/16.

> Gladman DD ndi Ritchlin C. Wodwala Information: Psoriatic Arthritis (Pambuyo pa Zowona). Zaposachedwa. Kusinthidwa 04/13/16.

> Helmick CG et al. Kukula kwa Psoriasis Pakati pa Akuluakulu ku US 2003-2006 ndi 2009-2010 Kafukufuku Wowona za Umoyo ndi Nutrition . Magazini ya American Medical Prevention Medicine . 2014.

> Psoriatic Arthritis, American College of Rheumatology. September 2013.