Zolakwitsa pa Kuphatikizana Zingapangitse Mavairasi a "Mutant" Akukana Kuchiza HIV
Kusamalitsa mankhwala kwa kachirombo ka HIV kumangotanthauzidwa kuti kusintha kwa maselo a kachilombo ka HIV, komwe kumathandiza kuti mavairasi ena asakane mankhwala ochepetsa tizilombo toyambitsa matenda . Pamene magulu a mavairasi otuluka mumtunduwu akupitirizabe kukula, amatha kukhala kachilombo koyambitsa matendawa mu "chidziwitso cha tizilombo." Izi zikachitika, kachilombo ka HIV kameneka kamakhala kochepa kwambiri mpaka mankhwalawo satha.
Mankhwala atsopano a antiretroviral amayamba kukhala ochepa pang'onopang'ono, ngakhale kunyalanyaza mankhwala osokoneza bongo kungawonjezere chiopsezo chotsutsa mwa kulola kuti tizilombo toyambitsa matenda (kuphatikizapo tizilombo toyambitsa matenda) kuti tibwerere mosavuta.
Chifukwa chiyani kusamvana kwa HIV kumayamba?
Pamene maselo amabala, amapanga makope enieniwo, akukula mu chiwerengero ndi kubwezeretsa. Koma kachilombo ka HIV kamakhala kolakwika ndi zolakwika za zolemba, zomwe makopewo amatha kukhala olakwika kapena owonongeka. Kaŵirikaŵiri izo siziri, izi zofooka "mutant" zimasintha mwamsanga.
Nthawi zina, nthawi zina zimakhala zosiyana. M'malo mofera, mavairasi ena amatha kuphuka chifukwa chidziwitso chawo chosasinthika sichilola kuti mankhwala omwe ali ndi kachilombo ka HIV agwirizane, alowetseni kapena amangirire kwa iwo. Choncho ngakhale mankhwalawa amatha kupha matenda oyambirira (omwe amadziwika kuti ndi "mtundu wamtundu" ), "mitundu" yotembenuzidwayo imatenga pang'onopang'ono kuti ikhale yovuta kwambiri.
Mankhwala amtunduwu amatha kupitsidwanso kuchokera kwa munthu kudzera mwa kugonana, kugwiritsidwa ntchito pogwiritsa ntchito singano, kapena kuwonetsetsa magazi.
Ngati kuperewera kwa mankhwala kumachitika chifukwa cha kusagwiritsidwa ntchito kwa mankhwala osokoneza bongo, magulu ena a mankhwala amalembedwa kuti athetsere mitundu yambiri mkati mwa piritsi la munthu.
Onani momwe kachilombo ka HIV kamayambira mu chidziwitso, gawo khumi .
Mmene mungazindikire ndi kutsimikizira kuti HIV ikutsutsana ndi mankhwala
Pali njira zosavuta zamagazi zomwe zimatha kuzindikira kukaniza kwa HIV ndikuthandizira madokotala kuti adziwe mankhwala ati omwe angagwiritse ntchito mankhwalawa.
Mitundu iŵiri ya kuyezetsa kuyesedwa kotchedwa genotypic ndi phenotypic testay imatha kuzindikira, momwemo, zomwe zimayambitsa kusintha kwa thupi ndi kusintha kwake kwakukulu.
- Zolemba za Genotypic zimayang'anitsitsa zolembera za kachilombo ka HIV, poyamba
kukweza ma genealo ndikuyang'anitsitsa kuona momwe kusintha komweku kungafanane ndi HIV. Katswiri wa chifuwachi amatha kulingalira kuti zomwe zimatsutsana ndizomwe zimachokera ku chimodzi kapena zingapo zosiyana siyana. Kusiyana kwa "chinthu chimodzi" kumatsutsana kwambiri, pamene ena amaonedwa kuti ndi achichepere ndipo amathandiza kukana. - Kuyeza kwaphenotypic kumasiyana ndi kuyesera kwa genotypic chifukwa kumatengera kachilomboko ndikuwonekera pamagulu osiyanasiyana a kachilombo ka HIV. Pochita zimenezi, amapereka odwala matendawa "zenizeni," umboni wosatsutsika wa mankhwala osokoneza bongo.
Mayeserowa amagwiritsidwa ntchito nthawi zambiri kuti adziwe njira yabwino kwambiri yothandizira pa mzere woyamba komanso mankhwala ochiritsira ku US ndi mayiko ena olemera. Komabe, mtengo wa genotyping ndi phenotyping amaonedwa kuti ndi oletsedwa m'madera ambiri osauka, omwe amagwiritsidwa ntchito makamaka kwa odwala okhaokha.
Pakalipano makampani ambiri a inshuwalansi ku US, onse payekha komanso pagulu, amapereka mayeso a genotypic.
Kuyezetsa kwa phenotype sikungapangidwe ndi ena a inshuwalansi. Nthawi zonse funsani ndi inshuwalansi wanu kuti mutsimikize ngati mayeserowa akuphatikizidwa mu phukusi lanu lopindulitsa.
Phunzirani zambiri zokhudza momwe kachilombo ka HIV ndi phenotyping zimagwirira ntchito .
Zotsatira:
Bungwe la World Health Organization (WHO). "Kachilombo ka HIV kotsutsa mankhwala." Geneva, Switzerland; April 11, 2011.
Taniguchi, T .; Nuritdinova, D ;; Grubb, J .; et al. "Kupatsirana kwa HIV kosagwiritsidwa ntchito mankhwala osagwiritsidwa ntchito mopitirira muyeso kumafala kwambiri ndipo kumakhudza zotsatira za virologic ngakhale mankhwala opatsirana pogwiritsa ntchito antiretroviral." AIDS Research Retroviruses Anthu. March 5, 2012; 28 (3): 259-264.
Kuhn, L .; Kudana, G ;; Technau, K; et al. "Kupewa mankhwala osokoneza bongo pakati pa ana omwe angoyamba kumene kutenga kachilombo ka HIV m'nthaŵi zowonjezereka za mankhwala opatsirana pogonana." AIDS. April 30, 2014; 8: 1673-1678.
National Institutes of Health (NIH). "Malangizo Othandizira Ogwiritsa Ntchito Matenda Ochepetsa Matenda a Edzi omwe ali ndi kachirombo ka HIV ndi 1 omwe ali ndi kachilombo koyambitsa matenda." Bethesda, Maryland; October 11, 2013.