Matenda othamanga ndi achibadwa chosabadwa kapena mabadwa omwe amachititsa minofu yogwirizana m'thupi. Makamaka, anthu omwe ali ndi matenda a Stickler amakhala ndi kusintha kwa majini omwe amapangitsa collagen. Zosintha za majinizi zingayambitse zina kapena zizindikiro zotsatirazi za matenda a Stickler:
- Mavuto a maso - kuphatikizapo kuyang'anitsitsa, kuchepa kwa thupi, glaucoma , cataracts , ndi mabowo a retina kapena maseti. Nthawi zina, mavuto a maso omwe amagwirizanitsidwa ndi Stickler Syndrome amachititsa khungu.
- Zovuta pakati pa khutu la pakati lomwe lingayambitse kupweteka, kumverera kapena kupweteka kwa kumva, makutu afupipafupi , makutu m'makutu kapena kuthamanga kwa mafupa a khutu.
- Ziphuphu zosaoneka bwino kuphatikizapo msana wam'mimba (scoliosis kapena kyphosis), mafupa osakanikirana, nyamakazi yoyamba, chifuwa cha chifuwa, matenda osokonezeka a ubwana (omwe amatchedwa matenda a Legg-Calve-Perthe), ndi mavuto a mgwirizanowu.
- Anthu omwe ali ndi matenda a Stickler angakhale ndi chiwerengero chachikulu cha mitral valve prolapse kuposa anthu ambiri, malinga ndi kafukufuku wina.
- Mankhwala osavuta kuphatikizapo malocclusion.
- Nthaŵi zina mawonekedwe a nkhope yonyezimira amawatcha kuti "Rob Robin". Izi nthawi zambiri zimaphatikizapo zinthu monga phale , bifid uvula, palate yapamwamba, lilime lomwe limabwerera mmbuyo kuposa lachidziwitso, chinyafupi, ndi fupa laling'ono. Malingana ndi kulemera kwa nkhope izi (zomwe zimasiyanasiyana pakati pa anthu), izi zikhoza kuyambitsa mavuto odyetsa, makamaka akhanda.
- Zina zikhoza kukhala hypertonia , mapazi otsika, ndi zala zala.
Matenda otetezeka ndi ofanana kwambiri ndi matenda otchedwa Marshall matenda, ngakhale kuti anthu omwe ali ndi matenda a Marshall amakhala ndifupikitsa kuwonjezera pa zizindikiro zambiri za matenda otchedwa Stickler syndrome. Matenda osokoneza amagawidwa m'magulu asanu aang'ono malingana ndi zizindikiro zomwe zatchulidwa kale.
Zizindikiro ndi kuuma zimasiyana kwambiri pakati pa anthu omwe ali ndi matenda a Stickler ngakhale m'mabanja omwewo.
Zimayambitsa
Chiŵerengero cha Stickler syndrome chiyenera kukhala pafupifupi 1 pa 7,500 kubadwa. Komabe, chikhalidwechi chikukhulupirira kuti sichikudziwika. Matenda osokoneza anadutsa kuchokera kwa makolo kupita kwa ana mwachitsanzo chodziwika bwino cha autosomal. Kuopsa kwa kholo ndi matenda a Stickler kupitirira mwana ndi 50 peresenti pa mimba iliyonse. Matenda otetezeka amapezeka pakati pa amuna ndi akazi.
Kudziwa
Matenda osokoneza angaganize ngati muli ndi zizindikiro za matendawa, makamaka ngati wina m'banja lanu apezeka ndi matenda a Stickler. Kuyeza kwa majeremusi kungakhale kothandiza pozindikira matenda a Stickler koma pakalipano palibe zofunikira zomwe zimagwiritsidwa ntchito ndichipatala.
Chithandizo
Palibe chithandizo cha matenda otchedwa Stickler matenda koma mankhwala ambiri ndi mankhwala amakhalapo kuti athetse zizindikiro za matenda a Stickler. Kuzindikira koyambirira kapena matenda a Stickler matenda n'kofunika kwambiri kuti zinthu zogwirizana zikhoza kuyang'aniridwa ndikuchitidwa mwamsanga. Kukonza opaleshoni ya nkhope yosaoneka ngati pirate palate kungakhale kofunikira kuthandizira kudya ndi kupuma.
Malingaliro opaleshoni kapena opaleshoni angapindule pochiza mavuto a maso. Zothandizira kumva kapena opaleshoni monga kupaka ma tubes akhoza kuteteza kapena kumvetsera mavuto. Nthawi zina ma anti-inflammatory mankhwala angathandize pochiza matenda a nyamakazi kapena mavuto amodzi.
Zotsatira:
Zolemba za Kunyumba za Genetics. Stickler Syndrome. https://ghr.nlm.nih.gov/condition/stickler-syndrome
Marfan Foundation. Stickler Syndrome. https://www.marfan.org/stickler-syndrome.
National Organisation for Disorder Disorders. Stickler Syndrome. http://rarediseases.org/rare-diseases/stickler-syndrome/.