Zimene Anthu Omwe Ali ndi Matenda a Shuga Ayenera Kudziwa Zokhudza Metformin

Metformin (mayina otchedwa Fortamet, Glucophage, Glumteza, Glucophage XR, Riomet) ndi mankhwala ovomerezeka pamlomo omwe amagwiritsidwa ntchito okha kapena mankhwala ena ochizira matenda a shuga. Ndi FDA yomwe inavomerezedwa mu 1994 ndipo ikupezeka ngati mankhwala a rosiglitazone / metformin (Avandamet).

Dos ndi Dont

Metformin imathandiza kuchepetsa shuga m'magazi m'njira zitatu:

1. Amachepetsa kuchuluka kwake kwa shuga umene umatengedwa kuchokera ku chakudya.

1. Amachepetsa kuchuluka kwa shuga zomwe zimapangidwa ndi chiwindi.
2. Zimathandiza kuti thupi liziyankhidwa ndi insulini.

Metformin sichitsitsa tsatanetsatane wa shuga wa magazi monga insulini. Choncho, si koyenera kwa odwala omwe ali ndi matenda a shuga omwe alibe mtundu uliwonse wa insulini.

Amene Saliyenera Kuligwiritsa Ntchito

Anthu omwe ali ndi kachilombo ka shuga (insulin) amadwala matenda a shuga, matenda a impso , kapena kusagwirizana ndi impso asagwiritse ntchito. Ngakhalenso ana asanakwanitse zaka 10. Ana osapitirira zaka 17 asagwiritse ntchito kutulutsidwa kwa metformin.

Mlingo

Metformin imatengedwa kawiri patsiku, makamaka ndi chakudya. Ngati mlingo waphonyezedwa, piritsi losowa liyenera kutengedwa mwamsanga, pokhapokha ngati ili pafupi nthawi ya mlingo wotsatira. "Kukayikakayika" pa mankhwala kuti mupange mlingo wosadziwika sayenera kuchitidwa.

Zotsatira Zotsatira ndi Ngozi

Metformin imayambitsa kutsekula m'mimba ngati itatengedwa popanda chakudya. Zotsatira zina zimaphatikizapo kukhumudwa m'mimba, kupaka mpweya ndi kuphulika, kukoma kwazitsulo, kupweteka mutu, chifuwa, ndi kupweteka kwa minofu.

Ngati metformin ilibe mphamvu ya shuga ya magazi, odwala kutenga metformin amatha kukhala ndi shuga wambiri wamagazi , ali ndi zizindikiro za chisokonezo, kugunda, kamwa youma, kusanza, mpweya wokoma, kapena kutaya chidziwitso. Aliyense amene akukumana ndi zizindikiro izi-kapena kupweteka pachifuwa, chiwombankhanga, kapena zizindikiro zina zoopsa-ayenera kufunafuna chithandizo chamankhwala mwamsanga.

Kawirikawiri, metformin ikhoza kuyambitsa lactic acidosis, matenda aakulu omwe amadziwika ndi lactic asidi mu magazi. Lactic acidosis, ngati osatulutsidwa, ingachititse kuti thupi lilephereke ngakhale kumangidwa kwa mtima. Zizindikiro zimaphatikizapo kutopa, kufooka, kupweteka kwa minofu, kupuma pang'ono, ndi kuunika.

Ngakhale ndizovuta ngati palibe mavuto ena azachipatala, kuwonjezera pa mankhwala osokoneza bongo kapena kugwiritsira ntchito mankhwala osokoneza bongo, metformin ikhoza kuyambitsa shuga wotsika magazi (hypoglycemia), yomwe imadziwika ndi chizunguliro, kunjenjemera, kutuluka thukuta, kusokonezeka, kapena kupweteka kapena kuzungulira pakamwa.

Zolemba Zopuma

Metformin ingagwiritsidwe ntchito kuchoka pamatope kuti ithandize kulemera kwa thupi, matenda a pocystic ovary, gestational matenda a shuga komanso HIV lipodystrophy syndrome.

Malangizo ndi Kusamala

Anthu omwe ali ndi matenda a shuga ayenera kutsatira zakudya zoyenera komanso mapulogalamu olimbitsa thupi monga akulimbikitsidwa ndi ogwira ntchito zaumoyo. Zakudya sayenera kudumpha ndipo kumwa mowa muyenera kupeŵa.

Mankhwala atsopano komanso mankhwala owonjezera pa mankhwalawa sayenera kutengedwa popanda kuvomerezedwa ndi katswiri wa zamankhwala. Kuonjezera apo, anthu omwe ali ndi matenda a shuga amayenera kufufuza nthawi zonse kuti ayang'ane matenda awo a shuga, kuphatikizapo kuyesa magazi kuti aone ngati ali ndi shuga (HbA1c).

Metformin iyenera kuthetsedwa kwa maola 48 isanayambe njira iliyonse ya mano kapena opaleshoni ndipo isanalandire kusiyana kosiyana (ie ndi CT scans). Ndikofunika kuti anthu omwe ali pa metformin afotokoze azimayi awo othandizira zaumoyo kuti azitenga.

_Zotsatira:

_{"Metformin: Dokotala wodziwa za mankhwala." Kupititsa patsogolo pa Intaneti. 2007. UpToDate.}

_{"Metformin: Kudziŵa mankhwala osokoneza bongo." Yambani pa Intaneti. 2007. UpToDate.}

_{"GlaxoSmithKline Adalengeza Kuvomereza kwa FDA ndi Kuyamba kwa Avandamet® (rosiglitazone maleate ndi metformin HCl) monga Initial Therapy mu Chithandizo cha mtundu wa shuga 2." GlaxoSmithKline. 11 Jul 2006. GlaxoSmithKline.}

_{"Metformin." Information Medx Plus Za mankhwala. 1 May 2007. Laibulale ya National Medicine ya US.}