Prednisone: Ubwino ndi Ngozi

Zotsatira zoyipa zimawonjezeka pamtunda ndi nthawi yogwiritsiridwa ntchito

Prednisone ndi mankhwala owopsa a corticosteroid omwe amagwiritsidwa ntchito pochizira matenda a nyamakazi komanso mitundu ina ya khansa ndi matenda omwe amachititsa kuti munthu asatengeke . Amapezeka pamapiritsi ndi madzi omwe amagwiritsidwa ntchito ngati mankhwala osokoneza bongo , kutentha thupi komanso kuteteza thupi lawo.

Momwe Prednisone Imagwirira Ntchito

Kutupa ndi njira ya thupi lachilengedwe pa chilichonse chimene chimati ndi chovulaza.

Pamene chitetezo cha mthupi chimadziwika ndi wothandizira, chimatulutsa mankhwala m'magazi omwe amachititsa kuti tizirombo tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda komanso kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda.

Ndi zovuta zina zomwe zimayambitsa matenda, chitetezo cha mthupi chimakhala chachilendo komanso chokwanira. Momwemonso ndi matenda a nyamakazi (RA) momwe chitetezo cha mthupi chidzasokoneza ziwalo zathanzi molakwika. Zizindikiro zovuta za RA nthawi zambiri zimatha popanda kuzindikira, zimachititsa ululu wambiri, kutupa, ndi kuvulaza olowa nawo.

Prednisone ili ndi mphamvu zoteteza mazirawa mofulumira kuchepetsa kutupa mpaka mankhwala ena odana ndi nthendayi (DMARD) angathe kugwira ntchito. Ngakhale kuti DMARD monga Plaquenil (hydroxychloroquine) ndi Arava (leflunomide) zimayang'aniridwa kwambiri ndi chitetezo cha mthupi, zimakhala zochepa.

Mosiyana ndi zimenezi, prednisone imapereka chithandizo mwamsanga koma imakhala ndi zotsatira zochepa zomwe zimachepetsa ntchito yake, makamaka pa nthawi yayitali.

Mosiyana ndi DMARD, prednisone sichimawonekera pa selo kapena zinthu zina. M'malo mwake, imagwira ntchito, kusefukira thupi ndikukhudza mitundu yambiri ya maselo ndi ntchito. Ndi chifukwa chake prednisone imatha kupereka mpumulo pa dzanja limodzi ndikuyambitsa mavuto ena.

Zotsatira Zotsatira

Zotsatira zake za prednisone zikhoza kukhala zochepa mpaka zochepa.

Zimapezeka kawirikawiri pa mlingo wapamwamba kapena pogwiritsa ntchito nthawi yayitali.

Zotsatira zochepa zazing'ono zifanana ndi zina za mankhwala a corticosteroid ndipo zingaphatikizepo kusungira madzi, kusokonezeka m'mimba, ndi kuwonjezeka kwa shuga m'magazi.

Matenda amayamba, komabe, pamene mankhwala akupitirira kwa nthawi yaitali, akuwonjezeka mwamphamvu pamene nthawi kapena mlingo ukuwonjezeka. Zotsatirapo zingaphatikizepo:

• Kuthamanga kwa magazi
• Kupitiriza kutopa
• Kusintha kwa thupi kumasintha, kuphatikizapo mkwiyo wadzidzidzi
• Kusokonezeka kapena kusokonezeka
• Kusokonezeka maganizo ndi nkhawa
• Kusagona
• Kulemera kwalemera
• Kutentha kwakukulu kwa nkhope
• Kusakhazikika kwa msambo
• Peptic chilonda
• Masomphenya osasangalatsa, glaucoma , kapena cataracts
• Kufooka kwa minofu ndi atrophy
• Kupukuta kapena khungu
• Kulira kosavuta
• Kuwonjezeka kwa chiopsezo cha matenda chifukwa cha kuponderezedwa kwa chitetezo cha mthupi
• Osteoporosis ndi chiopsezo chowonjezeka cha ziphuphu
• Bone imfa ( osteonecrosis )
• Matenda a chiwindi ( hepatic steatosis )
• Psychosis
• Kukula mofulumira kwa ana

Kufotokozera Information

Prednisone imapezeka m'mawonekedwe onse omasulidwa mwamsanga. Pofuna kulandira RA kwa anthu akuluakulu, mankhwalawa amalembedwa motere:

• Prednisone yomasulidwa mwamsanga imayikidwa mu mlingo wa tsiku lililonse wa ma milligrams osachepera 10 patsiku atengedwa ndi DMARD.
• Prednisone yomwe imatulutsidwa nthawi yochepa imayikidwa pa mlingo wa ma miligramu asanu kuti ayambe, potsatira mlingo wochepetsera wotsika kwambiri kuti ukhale ndi zotsatira zabwino za kuchipatala.

Prednisone kawirikawiri imatengedwa ngati mlingo umodzi pakadutsa chakudya cham'mawa kuti zisawonongeke m'mimba.

Kwa anthu omwe ali ndi nyamakazi yovuta kwambiri, amatha kutengedwera pa nthawi yogona kuti achepetse kuuma kwa m'mawa ndi ululu.

Nthawi ya mankhwala iyenera kupangidwa payekha, kuyeza ubwino ndi zoopsa ndikusankha ngati chithandizo cha tsiku ndi tsiku kapena chamkati chiyenera.

Kuyanjana kwa Mankhwala

Prednisone amadziwika kuti ali ndi mankhwala ambiri osokoneza bongo. Nthawi zina, mankhwala osokoneza bongo angapangitse kuti adziwe kuti mankhwalawa ndi ofunika kwambiri.

Nthawi zina, prednisone ikhoza kusokoneza ntchito ya mankhwala achiwiri.

Kuyanjana kwa mankhwala osokonekera kumadziwika ndi:

• Maantibayotiki monga clarithromycin kapena rifampin
• Matenda oterewa monga Zoloft (sertraline) ndi Prozac (fluoxetine)
• Mankhwala osokoneza bongo monga carbamazepine ndi phenytoin
• Mankhwala osakaniza monga Diflucan (fluconazole) ndi Sporanox (itraconazole)
• Mankhwala osokoneza bongo monga Emend (aprepitant)
• Mankhwala a mphumu monga Accolate (zafirlukast)
• Aspirin
• Anthu ochepa magazi monga Coumadin (warfarin)
• Diuretics ("mapiritsi a madzi")
• Mankhwala a mtima monga verapamil, diltiazem, ndi amiodarone
• Mankhwala opweteka ngati Tagamet (cimetidine)
• Mankhwala a HIV monga Reyataz (atazanavir), Crixivan (indinavir), ndi Kaletra (lopinavir / ritonavir)
• Mankhwala opatsirana pogonana
• Mankhwala osokoneza bongo
• Other corticosteroids
• Wotchedwa St. John's Wort

Kuonjezerapo, mlingo waukulu kapena ntchito yayitali ya prednisone ingachepetse chitetezo cha mthupi ku katemera wina ndi kuwapangitsa kukhala opanda mphamvu. Ngati mwatengedwa kwambiri ndi prednisone, muyenera kuyembekezera osachepera miyezi itatu musanayambe kupeza katemera wamoyo .

Nthawi zonse onetsetsani kuti adalangize dokotala wanu mankhwala kapena mankhwala omwe mumakhala nawo, kaya ndi mankhwala, mankhwala osamalidwa, zitsamba, zakudya, kapena chikhalidwe.

Mfundo Zina

Pakati pa mimba, prednisone iyenera kugwiritsidwa ntchito pokhapokha ngati ikufunika. Sizinapangidwe kuti zimapweteka mwana wamasiye pa maphunziro a nyama. Mankhwalawa akhoza kuperekedwa kwa mwana wakhanda kupyolera mkaka wa m'mawere koma sadziwika kuti amachititsa vuto lililonse. Nthawi zonse muzilemetsa phindu ndi dokotala wanu musanayambe kumwa mankhwala.

Akulangizidwe kuti mawonekedwe a madziwa ali ndi shuga ndi mowa. Mwina mungafunikire kugwiritsa ntchito mapepala ngati china mwa zinthu izi chikukhudzanso matenda monga shuga kapena matenda a chiwindi.

Pomaliza, ngati mutatenga mankhwala a prednisone kwa kanthawi, musamasiye mankhwala mwamsanga. Kugwiritsa ntchito mankhwala pang'onopang'ono kudzakuthandizani kupeŵa kapena kuchepetsa zotsatira za zotsatira zomwe zimachitika mwadzidzidzi.

> Chitsime:

> Firestein, G ;; Budd, R .; Gabriel, S. et al. (2017) Kelley ndi Firestein's Bookbook ya Rheumatology (10th ed .). Philadelphia, Pennsylvania: Elsevier: ISBN: 9780323316965.