Olanzapine (Zyprexa) ndi imodzi mwa magulu atsopano oletsa antipsychotic otchedwa antipychotic atypical. Mankhwalawa amawoneka kuti ndi abwino kwa anthu omwe ali ndi Alzheimer kuposa mankhwala ena okalamba odwala matenda opatsirana pogonana. Komabe, Zyprexa sichivomerezedwa ndi US Food and Drug Administration pofuna kuchiza psychosis kwa achikulire odwala matenda a maganizo .
Olanzapine ndi gawo la mankhwala omwe amatchedwa psychotropics - mankhwala osokoneza bongo omwe amakhudza malingaliro. Mankhwala a antipsychotic ndi mankhwala a psychotropic omwe amachiza zizindikiro za schizophrenia monga ziwonongeko , kupweteka ndi kupusitsa .
Kodi mankhwala a Atypical antipsychotic ndi otani?
Mankhwala oteteza antipsychotic amatchulidwa kuti athe kusiyanitsa pakati pa antipsychotics atsopano ndi ena ochiritsira antipsychotics (monga Chlorpromazine (Thorazine) ndi haloperidol). Mankhwala oletsa antipsychotic anayamba kufalitsidwa m'ma 1980. Zyprexa inavomerezedwa ndi Food and Drug Administration (FDA) mu 1996.
Mankhwala oteteza antipsychotic amasiyana kwambiri ndipo akhala akugulitsidwa monga mankhwala omwe ali ndi zotsatira zochepa za m'mimba monga extrapyramidal zizindikiro ndi kuchepa kwa dyskinesia. Mankhwala oletsa antipsychotics amavomerezedwa kuti asamalire schizophrenia koma agwiritsanso ntchito anthu omwe ali ndi matenda ochititsa munthu kusinthasintha maganizo komanso odwala matenda ovutika maganizo.
Zotsatira Zotsatira za Zyprexa
Zotsatira zoyipa zambiri zimaphatikizapo:
- Akathisia (kumverera kwa kusakhoza kukhala chete)
- Kutsekedwa
- Kugona ndi kugwedezeka
- Kusamvana (kutsika kwa magazi)
- Chizungulire
- Kulemera kwalemera
- Kuwonjezeka kwa chiopsezo cha kuwonjezeka kwa shuga ndi shuga
- Kuopsa kwa kugwa
Zotsatira zowopsa kwambiri za m'mimba ndizo:
- Zizindikiro za extrapyramidal - zozizwitsa zokhazokha za mutu, khosi, mikono, thupi, kapena maso.
- Didikinesia ya Tardive - kusuntha kosasunthika pakamwa, m'chinenero, pamasaya, kapena m'maso. Ngozi imakula ndi ntchito yaitali.
Njira Zowonjezera za Zyprexa
Mapiritsi a Zyprexa amapezeka ngati mapiritsi omwe angatengedwe kamodzi patsiku, mu mphamvu monga 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg ndi 20 mg. Mankhwala amatha kutengedwa kapena osadya. Palibe kufufuza magazi nthawi zonse.
Zyprexa imapezekanso ndi maonekedwe omwe amasungunuka pakamwa pakalumikizidwa ndi sikwa, komanso jekeseni ya m'mimba (kuwombera).
Onetsetsani kuti mukuwerenga bwino malamulowa. Funsani za chirichonse chomwe simukudziwa ndi mankhwala anu kapena dokotala.
Chenjezo za Zyprexa ndi Anthu okhala ndi Dementia
Pali chiopsezo chowonjezeka cha imfa mwa anthu omwe ali ndi chifuwa chachikulu cha matenda a maganizo omwe amatenga mankhwala ophera antipsychotic - omwe ndi Zyprexa. Kafukufuku wapeza kuti ambiri mwa anthu omwe amwalirawo anali okhudzana ndi matenda a mtima (mwachitsanzo, mtima wosalimba) kapena matenda (mwachitsanzo, chibayo).
Ngakhale kuti Zyprexa sivomerezedwa kuti azisamalira achikulire omwe ali ndi matenda okhudza maganizo aumtima, nthawi zina amalembedwa "off-label" (osati monga kuvomerezedwa ndi FDA) ndi cholinga chochepetsera mavuto akuluakulu a khalidwe kapena psychosis.
Ngati mankhwala ogwiritsira ntchito antipsychotic amagwiritsidwa ntchito pazifukwazi, ziyenera kukhala pambuyo pa njira zina zosagwiritsira ntchito mankhwala ndi kuyesa kutsimikizira kuti khalidweli limapweteka munthu amene ali ndi chifuwa chachikulu chaumtima kapena anthu omwe ali nawo pafupi, .
Mankhwala ena a Antipsychotic Atypical
Mankhwala ena oletsa antipsychotic ndi awa:
- Quetiapine (Seroquel)
- Risperidone (Risperdal)
- Ariprazole (Abilify)
Mankhwalawa ali ndi zotsatira zosiyana, komanso zotsatira zake, kwa anthu onse komanso omwe ali ndi matenda a Alzheimer's.
Zomveka Zonse
Kawirikawiri amadziwika kuti ngakhale kufufuza kwina kuli kofunika, kupeĊµa- kapena kugwiritsa ntchito mosamala mosamala ndi dokotala-akufunidwa pamene akulingalira Zyprexa kwa anthu omwe ali ndi matenda a maganizo.
Zotsatira:
Eli Lilly. Zyprexa. Idapezeka pa February 27, 2016. http://pi.lilly.com/us/zyprexa-pi.pdf
Laibulale ya National National Medicine. Olanzapine. December 12, 2015. https://www.nlm.nih.gov/medlineplus/druginfo/meds/a601213.html
-Edited by Esther Heerema, MSW