Momwe Lymphoma Markers Akuthandizira pa Kuzindikira Lymphoma pa Mimba Yambiri
Kodi ndi zizindikiro zotani za mitsempha yotchedwa Lymphoma, kapena CD? Nchifukwa chiyani ali ofunikira komanso amathandiza motani pakamapiritsa maimfine?
Kufunika kwa CD Lymphoma Markers
Kusankha ma CD pamatenda am'thupi n'kofunika kwambiri pakusankha mankhwala ochiritsira matendawa, koma sikunalipo nthawi zonse. Tiyeni tiwone mbiriyo kuti tidziwe kufunikira kwa mayeserowa pozindikira njira yabwino yothandizira khansa yanu.
Chifukwa chiyani Malipoti a Lymphoma ndi ofunikira
Yesani kulingalira mtundu umodzi wa selo wopereka pafupifupi mitundu makumi atatu ya khansara - zonsezi ndi dzina limodzi. Mankhwala amtundu wina angakhalepo m'matumbo anu, monga ubongo mu ubongo wanu, ngati matenda a m'mimba mwanu, kapena ngati mumataya khungu lanu lonse. Sikuti ndi nkhani yokha - malo amodzi amodzi mwa malo amenewa angakhale amodzi mwa mitundu. Ndipo kusankha chithandizo chabwino kumadalira kudziwa mtundu weniweniwo.
Microscope Sikokwanira Kufufuza Matenda Akumaliseche
Ngakhale zaka makumi angapo zapitazo, zomwe adokotala anaziwona pansi pa microscope ndi zida zosavuta zinali zonse zomwe tinkayenera kudziwa mtundu wa lymphoma. Ndipo panali mitundu yochepa chabe ya lymphoma yomwe ingakhale yosiyana. Komabe, nthawi zambiri zimakhala kuti khalidwe la mtundu womwewo ndi wosiyana ndi anthu osiyanasiyana. Mwachiwonekere, ife tinasowa chinachake.
Chothandizira Chili M'Mamolekyuli
Monga mankhwala osunthira kuchokera ku maselo kupita ku mamolekyulu, njira zinkakonzedwa kuti zizindikire mamolekyu ena omwe anapezeka pamwamba pa maselo.
Pamene izi zinkagwiritsidwa ntchito ku maselo a lymphoma, zinthu zinasintha kwambiri. Zinaoneka kuti ma lymphomasi sanali ochepa chabe, koma zovuta kwambiri.
Kodi zizindikiro za CD za Lymphoma ndi ziti?
Pamwamba pa ma lymphocytes, maselo omwe amasandulika kukhala malimphomasi, amatha malekyulo apadera.
Izi zinatchedwa "kusiyana pakati pa magulu" kapena CD . Monga ma lymphocyte wamba amayamba kuchokera ku maselo atsopano mpaka maselo okhwima, zizindikirozi zimasintha. Anapezeka kuti ma lymphomas omwe ankawoneka ngati ofanana ndi microscope anali ndi zizindikiro zosiyana pamwamba pawo. Pamene izo zinachitika, iwo ankachita ngati matenda osiyana palimodzi.
Ma CD a Lymphoma mu Kutulukira
Masiku ano, matenda a lymphoma samangokwanira kupatula ngati zizindikiro zochepa za lymphoma zimapezeka poyamba. Poika mtundu wina wa lymphoma m'thupi lomwelo, immunohistochemistry imagwiritsidwa ntchito pozindikira ma molekyuluwa pa maselo a zinyama.
Tsopano tili ndi mankhwala enaake omwe amawononga ma molekyulu a CD pamwamba pa maselo ena a lymphoma. Mankhwalawa - amatchedwa antiocidal antibodies - amayambitsa maselo okha omwe ali ndi chizindikiro cha CD.
Chitsanzo chapadera chingathe kumvetsetsa mosavuta. Ndi maimfine, zingakhale zovuta ngati sizingatheke kusiyanitsa pakati pa mitundu ingapo ya khansa. Mafupa ena ali ndi maselo a B cell ndipo ena ali T cell lymphomas, koma maselo a B ndi maselo T akhoza kuwoneka mofanana pansi pa microscope. Ngakhale kuti amawoneka ofanana, khansa yokhudza maselowa akhoza kuchita mosiyana kwambiri ndikuyankha mosiyana ndi mankhwala osiyanasiyana.
CD20 ndi chizindikiro kapena antigen chopezeka pamwamba pa maselo B koma osati maselo T. Kufalitsa mliri waukulu wa B cell lymphoma (DLBCL) - khansara ya maselo a B - angayang'ane ofanana ndi aplastic lalikulu cell lymphoma - khansa ya T maselo - pansi pa microscope. Komabe, mayeso a immunohistochemistry angatsimikizire kupezeka kwa CD20 - antigen yomwe imapezeka pa maselo a B pofuna kutsimikizira kuti khansara ndi DLBCL osati aplastic lalikulu cell lymphoma. Anaplastic lalikulu cell lymphoma, mosiyana, akhoza kusiyanitsidwa ndi kukhalapo kwa CD30 antigen.
Lymphoma Markers pakuzindikira Chithandizo ndi Matenda
Izo siziima pamenepo. Zina zamtengo wapatali (mmodzi wa iwo wotchedwa bcl-2) angakhoze ngakhale kumuwuza dokotala momwe matenda anu angakhalire bwino.
Ena ena (monga CD20) ndi pointer ngati chithandizo china chidzagwira ntchito. Zitsanzo za zolemba za CD zomwe zimakhudzidwa ndi mankhwala a lymphoma zikuphatikizapo monoclonal antibody Rituxan (rituximab) yomwe imafuna kuti antigen ya CD20 ikhale pamwamba pa maselo ena a lymphoma komanso maselo ena omwe amatha kukhala ndi khansa ya m'magazi.
Pamene kafukufuku wochuluka akulowa mu zizindikirozi, ntchito zatsopano zikubwera nthawi zonse. Zoonadi, lymphoma yalowa m'nthaŵi ya mamolekyu.
Zotsatira:
National Cancer Institute. Zolemba Zosokoneza. Kusinthidwa 11/04/15. http://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis/tumor-markers-fact-sheet