Katswiri wanu wamagetsi angakhale atalimbikitsa jekeseni wa Neupogen ngati muli ndi chemotherapy pa khansa ya m'mawere. Kodi cholinga cha jekeseni iyi ndi chiyani, nanga zimakhala zotani?
Mwachidule
Neupogen (filgrastim) ndi mankhwala operekedwa kwa anthu omwe amalandira mankhwala a chemotherapy amene ali ndi chiwerengero chochepa cha neutrophil ( mankhwala a chemotherapy omwe amachititsidwa ndi neutropenia .) Neutrophils ndi mtundu wa selo loyera la magazi lomwe limathandiza kupewa matenda.
Neupogen amagwira ntchito polimbikitsa fupa la mafupa kuti liwonjezere kupanga maselo oyera a magazi. Ndi madzi omveka omwe amaperekedwa ngati mphutsi (jekeseni.)
Neupogen ingaperekedwe mwamsanga pambuyo pa mankhwala a chemotherapy omwe angachepetse kwambiri kuwerengera kwa neutrophil (monga dose kawiri Cytoxan ndi Adriamycin.) Nthawi zina zingaperekedwe ngati mayeso a magazi anu amasonyeza kuti chiwerengero chanu cha maselo oyera, makamaka chiwerengero chanu cha neutrophil, ndi wochepa kwambiri moti angakuike pangozi yaikulu kuti ukhale ndi matenda.
Neupogen mwa Anthu Amene Ali ndi Khansa ya M'mimba
Chemotherapy pa khansa ya m'mawere imakhudza zonse zomwe zikugawanika maselo m'thupi lanu mofulumira, kuphatikizapo maselo a m'mafupa omwe amapanga maselo oyera a magazi, maselo ofiira, ndi mapulogalamu. Maselo onse a magaziwa atachepetsedwa, amatchulidwa ngati mankhwala a mafupa a mankhwala a chemotherapy.
Ngakhale kuti anthu angathe kukhala ndi maselo ofiira a m'magazi ( chemotherapy-anduced anemia ) ndi mapiritsi (chemotherapy -ducedduced thrombocytopenia) kawirikawiri amakhala otsika kwambiri a neutrophils (omwe amatchedwa neutrophils) omwe amachititsa ngozi kwambiri.
Pa chemotherapy, wanu oncologist adzayang'ana CBC yanu nthawi zambiri.
Mmene Neupogen Imagwirira Ntchito
Kawirikawiri, thupi lanu limapanga mapuloteni omwe amachititsa kuti ma neutrophils apangidwe mu hematopoiesis . Koma pa chemo kwa khansa ya m'mawere, thupi lanu silingapange mapuloteni okwanira. CBC yanu ingasonyeze kuti ziwerengero zanu zamagazi za neutrophil ndizochepa ndipo ndinu a neutropenic.
Majekeseni a Neupogen adzakuthandizani kupanga ma neutrophils. Mutha kumverera kupweteka ndi kupweteka kwa mafupa pamene mankhwalawa akugwira ntchito, koma zingakuthandizeni kulingalira kuti chitetezo chanu cha mthupi chimadzimangirira komanso kuti chiteteze thanzi lanu.
Ulamuliro
Mudzakhala ndi jekeseni ya Neupogen kamodzi tsiku lililonse mpaka minofu yanu yoyera ya magazi ifike kumayendedwe abwino. Mukamapatsidwa bwino, majekiseni sangapweteke. Mankhwalawa amatha kuperekanso kudzera mu kulowetsedwa m'mimba (IV).
Zotsatira Zotsatira
Sikuti onse adzakhala ndi zotsatirapo pa Neupogen, koma kupweteka kwa mafupa onse ndi malungo ndizofala. Kupweteka kumakhala ngati kumakhala kwakukulu m'madera a thupi lanu kumene maselo ambiri amagazi anu amapangidwa, monga chifuwa chanu, miyendo yanu yapamwamba, ndi pelvis yanu.
Kawirikawiri, mankhwala sakufunika kuti ululu wa phungu usalankhule koma uzani dokotala wanu pasanapite nthawi. Angakulimbikitseni kuti mutenge Tylenol (acetaminophen) kapena Advil (ibuprofen) koma, popeza mankhwala angathe kuthandizana kapena kuchititsa mavuto ngati chiwindi kapena impso sizigwira ntchito bwino, ndikofunika kutsegula izi posachedwa. Anthu ambiri amadziwa kuti kuyamwa mumsamba wotentha kumathandiza kuchepetsa kupweteka kwa mafupa.
Kodi Muyenera Kuitanira Dokotala Wanu Nthawi Yanji?
Nthawi zina zimakhala zochitika ndipo muyenera kutchula dokotala nthawi yomweyo ngati mukufuna kukhala:
- Zomwe zimayambitsa matenda (ming'oma; vuto kupuma, kutupa kwa nkhope, milomo, lilime kapena mmero, kutupa kufalikira thupi lanu)
- Kupweteka m'mimba
- Kumva ululu
Muyeneranso kutchula dokotala wanu ngati mukumva kupweteka kwa chifuwa, kupotoza mtima, kapena kutopa kwachilendo.
Ngozi
Neupogen ndi mankhwala abwino kwambiri omwe amagwiritsidwa ntchito pa mitundu yambiri ya neutropenia. Kaŵirikaŵiri palibe mankhwala kapena osatha kuchokera ku mankhwalawa. Zotsatira zilizonse zomwe mumakumana nazo zidzasiya ndi kusiya pamene mukusiya kulandira Neupogen shots. Pakhala pali vuto la kupweteka kwa mpeni chifukwa cha imfa, ngakhale izi ndizosowa kwambiri.
Ndani Ayenera Kupewa Mankhwalawa?
Musatenge mankhwala awa ngati:
- Iwe uli ndi pakati kapena kuyamwitsa
- Mukulimbana ndi Neupogen
Malangizo
Musanayambe jekeseni yanu yoyamba ya Neupogen, dokotala wanu adzalamula ma CBC kuti azipeza mapepala anu, maselo ofiira ndi oyera, ndi neutrophils. Pamene chithandizo chikula, pitirizani kuyesera kuyesa magazi. Izi ndi zofunika pamene ayang'ana momwe Neupogen alili komanso kuti mukupeza mlingo woyenera.
Ngati mukuyamwitsa kapena mutatenga, kambiranani ndi dokotala musanatenge Neupogen. Sipanakhale kafukufuku wokwanira kuti adziwe zotsatira za mankhwalawa pa mkaka wa m'mawere kapena mwana wa munthu.
Mfundo Yofunika Kwambiri
Neupogen (kapena Neulasta ) ikhoza kukhala yothandiza kwambiri kuti muwonjezere mlingo wa neutrophils mu thupi lanu kuti muchepetse chiopsezo chanu cha matenda. Zili zofunikabe, komabe, kusamala ndi kuchita zinthu zomwe zingachepetse chiopsezo chotenga kachilombo ka mankhwala monga mankhwala osamba m'manja komanso kupewa odwala.
> Zotsatira:
> Lee, K., Kim, J., Lee, M. et al. Phunziro lachidziwitso, la Multicenter, la Phase II / III Phunziro lokhazikitsa Phunziro lokhazikika ndi Kuwona Kuchita bwino ndi Chitetezo cha Pegteograstim pa Chemotherapy-Kuchokera kwa Neutropenia Poyerekeza ndi Pegfilgrastim M'chifuwa cha khansa ya m'mimba: KCSG PC10-09. Thandizo Lothandiza ku Khansa . 2016. 24: 1709-1717.