Nancy anali ndi mankhwala a chemotherapy kumayambiriro kwa zaka za m'ma 1980 kuti kansera yake ya m'mawere ibwererenso . Kalelo, mankhwala a chemo anaperekedwa mowonjezereka kuposa momwe akuchitira panopa, ndipo ocheperako amadziwika kuti amateteza zotsatira zake. Anayamba kudwala komanso kufooka panthawi yachipatala, ndipo chimodzi mwa mankhwalawa chinamupangitsa kukhala wosawona khungu. Zaka makumi awiri kenako, pamene ndinatenga chemo, mlingo wa mankhwalawo unali waung'ono ndipo chithandizo chamankhwala chisanayambe chinaperekedwa kuchoka ku zotsatira zoipa kwambiri.
Mankhwala a khemotherapy kwa khansa ya m'mawere yakula bwino, ndipo miyoyo ya anthu ikukhala bwino.
Pofuna kukuthandizani kumvetsetsa zofunikira za mankhwala a chemotherapy, momwe zingakhudzire inu ndi chisankho chanu, ndinayang'ana zomwe akatswiri amanena pa UpToDate - mawu ovomerezeka omwe amagwiritsidwa ntchito ndi ambiri oncologists omwe amachititsa odwala khansa ya m'mawere.
Mukhoza kapena simusowa chemotherapy. Koma muyenera kudziwa ngati chemotherapy idzapindulitsani inu pokhala ndi mwayi wopulumuka. Yambani mwa kuwerenga ichi kuti muwone chifukwa chake chemotherapy ikhoza kukhala yofunikira kwa inu.
Malinga ndi UpToDate, chemotherapy imatanthauza kugwiritsa ntchito mankhwala kuti asiye kapena kuchepetsa kukula kwa maselo a kansa. Chemotherapy amagwira ntchito mwa kusokoneza luso la maselo okula mofulumira (monga maselo a khansa) kugawa kapena kuchulukana. Chifukwa chakuti maselo ambiri akuluakulu samagawanika kapena akuchulukitsa, iwo samakhudzidwa ndi chemotherapy.
Komabe, mafupa (kumene maselo amagazi amawombera), mapuloteni a tsitsi, ndi kutsalira kwa tsamba la m'mimba (GI) onse akukula. Zotsatira za mankhwala a chemotherapy zimakhudzana ndi zotsatira pa izi ndi zina zotere.
Kodi Chemotherapy N'chiyani?
Chemotherapy angatanthauzidwe kuti ndi mankhwala opangira mankhwala kuti athetse kapena kulamulira matenda.
Chemotherapy pa khansa ya m'mawere ndi mankhwala osokoneza bongo, omwe amakhudza maselo ambiri m'thupi lanu. Mankhwala amphamvu ameneĊµa amagwiritsidwa ntchito kupha kapena kuchepetsa kukula kwa maselo a khansa mwa kusokoneza DNA, kupanga mapuloteni, kulepheretsa maselo osagawanika, kuwapatsa njala, kapena kuteteza ma receptors.
Kodi Ndi Mankhwala Otani Amene Amagwiritsidwa Ntchito Kwa Khansa ya M'thupi?
Mankhwala ambiri ndi ma regimens amalimbana ndi khansa ya m'mawere. Nawa ena mwa mankhwalawa:
- CMF: Cytoxan (cyclophosphamide), methotrexate, ndi 5-FU (5-fluorouracil)
- AC: Adriamycin (doxorubicin) ndi Cytoxan
- CAF kapena FAC: Cytoxan, Adriamycin, ndi 5-FU
- CEF kapena FEC: Cytoxan, Ellence (epirubicin), ndi 5-FU
- TC: Taxotere (docetaxel) ndi Cytoxan
Kodi Ndikufunikira Mankhwala Owonjezera Othandizira Kudwala Khansa Yanga?
Matenda ena amafunika kuwonjezeranso mankhwala ena, kuwunikira mapuloteni enieni kapena kuchepetsa kutuluka kwa magazi ndi zakudya ku chotupacho. Njira imeneyi imatchedwa biologic therapy. Izi zikuphatikizapo:
- Herceptin wa HER2 Wathanzi wa khansa yabwino
- Tykerb (lapatinib) ya HER2 Yabwino ya Metastatic Breast Cancer
Avastin savomerezanso kuti azisamalidwa khansa ya m'mawere.
Kodi Chemotherapy Amachiritsidwa Motani?
Mankhwala ambiri okhudza tizilombo toyambitsa matenda a khansa amaperekedwa m'madzi amadzimadzi, monga intravenous infusions, kapena jekeseni, koma amapezeka ngati mapiritsi kapena mapiritsi.
Mankhwala ena akhoza kuperekedwa okha, ndipo mankhwala ena amasonkhana kuti agwire ntchito limodzi. Pamene mankhwala a chemo amaperekedwa pamodzi, mankhwalawa amatchedwa regimen . Kuchotsa mankhwala m'thupi kumaphatikizapo kuponderezedwa kwa masiku 7 mpaka 21.
Kawirikawiri, chemo imaperekedwa kamodzi pa milungu itatu iliyonse, ndipo mufunika nthawi yowonjezera kuti mubwezere magazi anu ndikulola mankhwalawa kugwira ntchito. Mlingo wochepa wa chemo umaperekedwa mlungu uliwonse, ngati mlingo wa mankhwala osokoneza bongo udzafunika kuchepa nthawi. Chemo yamlomo ikhoza kutengedwa tsiku ndi tsiku, kapena monga momwe yakhalira. Majekeseni angaperekedwe kale, nthawi, kapena pambuyo pa kulowetsedwa kwa chemo.
N'chifukwa Chiyani Chemotherapy Amayambitsa Zovuta Zina?
Chikhalidwe champhamvu cha chithandizo cha chemo ndi mphamvu zake komanso chifukwa chake cha mbiri yake yoipa pambali za zotsatirapo.
Chemo imafuna maselo okula mofulumira monga khansa. Zingasokonezenso maselo anu omwe amakula mofulumira monga magazi, minofu mumatumbo anu m'thupi lanu, chala ndi ziwalo , ndi tsitsi la tsitsi . Zotsatirazi zidzatha ngati mutatsiriza mankhwala.
Kodi Ndingapeze Bwanji Thandizo Kulimbana ndi Chithandizo?
Pambuyo pa chemo kulowetsedwa, mumapatsidwa mankhwala kuti muteteze kusuta ndi kusanza . Izi zikhoza kukhala mapiritsi, ena akhoza kukhala amadzi omwe amayidwa mumatope anu opatsirana. Mutatha kulowetsedwa, mungafunikire kumwa mankhwala osokoneza bongo, choncho onetsetsani kuti mwalemba mankhwalawa musanayambe kumwa mankhwala. Mukhozanso kupatsidwa mankhwala oletsa antigengenic, kapena zinthu zina kuti muteteze matenda anu abwino. Onetsetsani kuti dokotala wanu ndi anamwino adziwe mavuto omwe mukukumana nawo, komanso kuti ndi otani. Funsani chithandizo kuthandizira zotsatira zake. Kawirikawiri, zizindikirozo zimachepetsedwa kapena kutetezedwa.
Chemotherapy Zimakhudza Zochitika Panu Pano Ndiponso Zotsatira Zam'tsogolo
Ngati ndinu mtsogoleri woyamba musanayambe kulandira chithandizo, dziwani kuti chemo ikhoza kukupangitsani kuti musakhalenso ndi nthawi yopuma . Nthawi yanu ingayime, ndipo mukhoza kuchipatala , zomwe zingakhale zosakhalitsa kapena zosatha. Mankhwala odziwika bwino a chemo amadziwika kuti amachititsa kuti asabereke.
Ngati muli ndi maganizo okhudza mimba yam'tsogolo, lolani oncologist wanu adziwe musanayambe mankhwala. Funsani zomwe mungasankhe ngati mukukonzekera kuwonjezera pa banja lanu. Malinga ndi msinkhu wanu, mankhwala ozunguza bongo, ndi mlingo, kubereka kwanu kungabwererenso pambuyo chithandizo. Koma ngati pali mwayi kuti mutha kukhala wosabereka, muyenera kudziwa musanayambe kukupatsani mankhwala.
> Chitsime
> Harold Burstein, MD, Ph.D. "Adjuvant chemotherapy ndi trastuzumab (Herceptin) kwa khansa ya m'mawere oyambirira." UpToDate.