Kuyambira Kuchiza Kuchiyambi kwa Kansa ya Prostate ya Metastatic

Mu 2010 a FDA adavomereza Katemera wa khansa ya prostate yowononga mahomoni. Kupereka ndi mankhwala omwe amathandiza kupititsa patsogolo chitetezo cha mthupi. Anthu ena otsutsa amachititsa kuti zitheke kuyankha mafunsowa chifukwa chakuti njira zambiri zothandizira khansa zimaonekera poyerekeza ndi PSA. Komabe, ndi makina a Provenge therapy PSA nthawi zambiri sasiya.

Popeza ndayang'anitsitsa ndekha anthu mazana angapo opatsidwa chithandizo, ndakhala ndikuwona zochitika zazikulu zomwe Njira zowonjezera PSA. Komabe, kuchepa kwa PSA sizomwe mukulamulira nthawi zambiri PSA ikupitirizabe kukwera pambuyo pa Provenge.

Ngati PSA sichitha, kodi mungatani kuti mupitirizebe kupulumuka nthawi yaitali? Ambiri amaiwala kuti ngakhale kuti mankhwala amatha kumapeto kwa milungu isanu ndi umodzi, chitetezo cha mthupi chitangotsekedwa zotsatira zake zimapitirirabe. Choncho, ngakhale kupatsa ndiko kungowonjezera matenda ochepa kwambiri, kukula kosalekeza kwa khansa kumakhudza kwambiri nthawi. Kwa zaka zambiri, ngakhale kuchepetsa kuchepa kungapangitse kuti phindu lalikulu likhalepo.

Kafukufuku

Ngati lingaliro lakuti Zopereka zimapangitsa kuti thupi likhale lofatsa, lokhalitsa ndi lolondola, ndiye amuna omwe amalandira chithandizo ndi Zopereka kale (omwe ali ndi nthawi yaitali yopulumuka) ayenera kulandira kupindula kwakukulu kuposa momwe amuna amachitira panthawi ina .

Poyesa izi, Dendreon, wopanga Zamagetsi anafufuza deta kuchokera ku maphunziro oyambirira omwe anatsogolera ku chivomerezo cha FDA. Chonde dziwani, ofufuza sanayerekeze kupulumuka kwa amuna omwe anachitidwa kale kusiyana ndi kupulumuka kwa amuna omwe anachitidwa mtsogolo. Mwachiwonekere, amuna omwe amachitira kale payekha amakhala moyo wautali.

M'malo mwake anafanizira kupulumuka kwa amuna opatsidwa mankhwala omwe ali ndi matenda oyamba kale omwe ali ndi amuna omwe amachititsa anthu odwala matendawa. Iwo anachitanso chimodzimodzi (Amuna opatsidwa mankhwala motsutsana ndi amuna ochiritsidwa ndi malo omwe amachitira operekera) amuna omwe ali ndi magawo osiyanasiyana a matenda osiyanasiyana kuyambira kumayambiriro mpaka kumapeto. Kwenikweni, anagawa amunawo m'magulu anayi: Kuyambira kale, sitepe yapakatikatikati, sitepe yapamwamba komanso sitepe. "Zigawo" zosiyana zimatanthauzidwa ndi momwe mkulu wa PSA analiri panthawi yomwe Chiyambi chinayambika. Mwachitsanzo, kumayambiriro koyamba anali PSA osachepera 22; Gawo laling'ono linali PSA pakati pa 22-50; malo apamwamba ndi PSA pakati pa 50-134; ndipo malo apamwamba anali PSA wamkulu kuposa 134.

Gome ili m'munsimu likufotokozera mwachidule zotsatira za kusanthula kwawo.

Monga momwe tikuonera kuchokera pa gome, magulu onse omwe adapatsidwa mankhwala, adawonetsera mwayi wopulumuka poyerekeza ndi siteji yomweyo omwe amachitira ndi placebo. Komabe, pamene Zopereka zinaperekedwa pachigawo choyambirira, zopindulitsa zapulumuka zinali zazikulu. Amuna omwe ali ndi gawo loyambirira (PSA <22) anakhala ndi miyezi 13 yaitali kuposa amuna ofanana nawo omwe anali opanga malo.

Amuna omwe ali ndi msinkhu wapamwamba amangokhala miyezi ingapo kuposa amuna ochiritsira malo omwe amapita patsogolo.

Njira imeneyi yopezera kupulumuka ndi matenda oyambirira akuoneka kuti ikugwirizana ndi lingaliro lakuti chiopsezo cha chitetezo cha chitetezo cha chitetezo cha chitetezo cha chitetezo cha mankhwala chimapangitsa kuti pang'onopang'ono chipulumutso chikhale chachikulu kwambiri pamene chiloledwa kuwonjezeka pa moyo wautali. Cholinga china chofotokozera deta iyi ndi chakuti kanthawi kakang'ono ka khansa ali ndi ma clones ochepa ndipo amamvera kwambiri mankhwalawa. Kaya ndilo lingaliro limodzi kapena lina, kapena zonsezi zitatengedwa pamodzi, umboni wakuti kale chithandizo cha mankhwala chikuthandizira zotsatira zikupitiriza kutsimikiziridwa nthawi zonse pamene mayesero amayesedwa.

Mosakayika, pogwiritsa ntchito detayi, munthu akhoza kungoganiza kuti Zopereka zimapindula kwambiri ngati ataperekedwa kale.