Adriamycin-amadziwikanso kuti Rubex, Doxil, doxorubicin ndi Red Devil (mawu osamveka) -wa mankhwala a chemotherapy . Makamaka, ndi mtundu wa antithrotic anthracycline omwe ndi mankhwala oletsa kuteteza thupi. Zimapangidwa kuchokera ku bacterium Streptomyces.
Zimagwiritsa ntchito Adriamycin
Adriamycin ingagwiritsidwe ntchito pofuna kuchiza khansa ya m'mawere, kanseri ya m'mawere ya HER2, ndi matenda a metastatic.
Nthawi zina Adriamycin amaphatikizidwa ndi Cytoxan ndi / kapena 5-fluorouracil kuti azidyera mankhwala a khansa ya m'mawere.
Mankhwalawa amavomerezedwa kuti asamalidwe ndi khansa zina, kuphatikizapo mazira, chikhodzodzo, minofu yofewa ndi osteogenic sarcoma, khansa yaing'ono ya mapapo, kansa ndi kansa ya m'mimba, komanso neuroblastoma, lymphoma, khansa ya m'magazi, zotupa zam'mimba ndi Kaposi's sarcoma.
Mmene Adriamycin Amagwirira Ntchito
Adriamycin amakangana ndi khansa pochepetsa kapena kuchepetsa kukula kwa maselo a khansa. Mankhwalawa amalowa m'maselo a khansa, amalowerera mkati mwa DNA ndipo amaletsa kubwezeretsa maselo poletsa ntchito ya puloteni yotchedwa topoisomerase-II. Adriamycin imapangitsanso mpweya wosagwiritsa ntchito mpweya wabwino, umene umapangitsa kuti maselo osakanikirana ndi mapuloteni asokoneze komanso angakhudze mtima.
Kodi Adriamycin Amaperekedwa Bwanji?
Mankhwalawa amaperekedwa ndi jekeseni panthawi yophatikizidwa ndi chemotherapy . Ngati mlingo wa Adriamycin womwe ukupatsidwa uli wandiweyani kwambiri, ungaperekedwe ngati jekeseni "kupitiliza," m'malo mopyola muyeso.
Mankhwala ofiirawa amagawidwa mu siringi yaikulu ya pulasitiki, yomwe idzaphatikizidwa ndi matayala anu a catheter, ndipo namwino wanu kulowetsedwa adzachepetsa pang'onopang'ono manyowawo, kuti ayese Adriamycin mu mitsempha yanu.
Asanayambe Kuchiza
Chifukwa mankhwalawa angayambitse mavuto a mtima, muyenera kukhala ndi MUGa scan , LVEF (kumapeto kwa ventricular failure) kapena kufufuza kwa moyo wa moyo mutangoyamba kumene kuchipatala.
Kuyeza koyambirira kumeneku kudzagwiritsidwa ntchito kuyerekezera ndi ntchito yanu yamtima panthawi ndi chithandizo. Mayesero ena a impso ndi chiwindi ntchito angakhalenso osowa.
Malangizo pa Chithandizo
- Gwiritsani ntchito njira zothandizira kulera - kupewa mimba
- Imwani madzi ambiri, makamaka madzi, kuti mugwedeze impso zanu ndi chikhodzodzo
- Pewani kumamwa mowa ndi khofi - izi zimayika minofu yanu
- Musatenge aspirin, chifukwa imayambitsa magazi anu
- Musapezeke katemera
Ngozi
- Zomwe zimayambitsa matendawa ndi adriamycin
- Lembani mwana wamwamuna, ngati mutatenga mimba mukamachiza
- Kusabereka kwa m'tsogolomu kotheka
- Kutsika kwa magazi , chiopsezo chachikulu cha matenda
- Nthaŵi zina, pamakhala kuwonongeka kwa mtima
Zotsatira Zowonongeka Zotheka
- Mtsuko wofiira woyamba masiku awiri mutatha kuchiza
- Neutropenia (kuchuluka kwa maselo oyera a magazi, chiopsezo chachikulu cha matenda)
- Matenda a Chemotherapy-omwe amachititsa kuti magazi asapitirire kuchepa.
- Thrombocytopenia ( chiwerengero chochepa cha platelet )
- Kutayika tsitsi, kapena tsitsi lopweteka
- Nausea
- Kuthamanga
- Kutsekula m'mimba
- Kutopa
- Mucositis (inakwiyitsa mucous memphane mkamwa mwanu, m'mimba, ndi m'magazi)
- Amenorrhea (kumapeto kwa msambo kumasiya)
- Kusintha kwa misomali (yovuta kapena yachikasu)
Nthawi yoitanira Dokotala Wanu
Ngati muli ndi zizindikiro izi, dinani dokotala wanu:
- Kutentha kwa 100.5F kapena kuposa
- Ululu kapena wofiira pa tsamba lanu lojambulidwa
- Msuzi wamagazi kapena thukuta lofiira
- Kuvulaza kosazolowereka kapena kuika magazi mosalekeza
- Chifuwa chopitirira, pakhosi, chibayo
- Zozizira zowononga: kupuma kwafupipafupi, kutupa kwa mapazi kapena mabotolo, kuthamanga, kutupa khosi kapena lirime
Chonde dziwani kuti Extravasation zimachitika pokhapokha mu kulowetsedwa.
Zotsatira
US Food and Drug Administration. FDA Doxorubicin Proposed PI Update. Mayina Ovomerezedwa Otsiriza - May 8, 2003.
National Cancer Institute. Information Drug - Doxorubicin Hydrochloride.
Medline Plus. Mankhwala Osokoneza Bongo. Doxorubicin.