Mankhwala atsopano Poyambirira Oyerekeza ndi Placebo
Pamene mankhwala atsopano atha kupezeka, ndi zachibadwa kukayikira momwe angafananire ndi zogwiritsira ntchito mankhwala omwe ali kale. Pankhani ya Hetlioz , yogulitsidwa pansi pa dzina la tasimelteon, ndikofunika kufufuza zothandiza pothana ndi Matenda Osapitirira 24-Kugona-Wake (Osati 24) . Kodi zikufanana bwanji ndi melatonin , chithandizo choyenera cha matendawa?
Kafukufuku Pakati pa Hetlioz ndi Melatonin
Panalibe mayesero ochita kafukufuku omwe amafanizira kugwiritsa ntchito Hetlio ndi melatonin pamutu wapamwamba. US Food and Drug Administration (FDA) inavomereza Hetlioz pogwiritsa ntchito mayesero olamulidwa ndi placebo. Izi zikutanthauza kuti Hetlioz, yomwe imagwira ntchito pa ubongo ku melatonin, inali yothandiza kwambiri pochiza Osati 24 kuposa mapiritsi a placebo. Mphamvu zake sizinafanane mwachindunji ndi kutenga melatonin yapamwamba, yomwe idakhala nthawi yoyang'anira chisamaliro ichi.
Malingaliro Aling'ono a Chithandizo
Mu malangizo ake omalizira kuchokera mu 2007, asanakhalepo ndi Hetlioz, American Academy of Sleep Medicine (AASM) imalimbikitsa kugwiritsa ntchito melatonin pochiza osakhala 24. Pofuna kutsimikiza kuti maseĊµera a circadian amadziwika bwino omwe angayambitse kugona ndi kugona mokwanira, melatonin ikhoza kukhala yothandiza kwambiri.
Kukhazikika uku kumatchedwa kuyendetsa. Zizindikiro za kugona ndi kugalamuka m'maso mwa anthu akhungu zimatha kugwirizana, kapena kuphunzitsidwa, ku machitidwe a usiku.
Izi zikhoza kuchitika ndi mlingo wotsika kwambiri wa melatonin yoposa. Ndikofunika kusankha munthu wolemekezeka yemwe amatsimikizira kuti zomwe zilipo ndi zabwino komanso zenizeni.
Kawirikawiri, mlingo wochepa (0,3 mg) ukhoza kugwiritsidwa ntchito popangira anthu akhungu omwe alibe 24. Poyerekeza, zambiri zowonjezera katundu zimakhala ndi 3 mg wa melatonin (nthawi 10 zofunikira) kapena zina zambiri. Mavitamini oterewa akhoza kusefukira, kusagwiritsanso ntchito zopindulitsa komanso zomwe zingabweretse mavuto.
Nthawi ya mlingo wa melatonin ndi yofunika kwambiri. Zingathenso kuthandizira katswiri wa kugona kuti atsimikizire kuti kuchuluka kwa mlingo ndi nthawi ndizoyenera.
Kuwona zotsatira za Chithandizo
Kodi mukudziwa bwanji ngati chithandizo chikugwira ntchito? Pambuyo pa kuwongolera kwazizindikiro, zingakhale zothandiza kufufuza momwe mankhwalawa akugwiritsidwira ntchito m'njira zina. Magalasi ogona ndi ma laboratory of circadian markers angakhale othandiza.
Chofunika kwambiri, kwa anthu omwe alibe 24 omwe sali akhungu, nthawi yowoneka bwino angakhale chithandizo chothandizira chothandizira.
Tikuyembekeza kuti kufufuza kwina kudzayesa kufanana pakati pa Hetlioz ndi melatonin, koma panthawiyi mungaganizire kukambirana za njira zomwe mungachite ndi katswiri wanu ogona kuti mupeze njira yabwino.
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