Gulu la Mavuto Limene Limapweteka Mitsempha Yanu Pang'onopang'ono
Matenda a Charcot-Marie-Tooth (CMT) amaimira gulu la mavuto omwe amachititsa zofooka m'mitsempha ya manja ndi miyendo yanu. Matendawa amatha kupangitsa kuti minofu ikhale yofooka, atrophy , komanso kutayika.
Mitundu ya Matenda a Charcot-Marie-Tooth
Pali mitundu yambiri ya matenda a Charcot-Marie-Tooth (CMT). Mu matenda a mtundu wa CMT, matendawa amakhudza chidutswa cha myelin , chophimba chophimba m'mitsempha.
Mu Matenda a mtundu wa CMT 2, mitsempha yokha imakhudzidwa. Mtundu wa CMT (matenda a Dejerine-Sottas), mtundu wa CMT 4, ndi CMT X, monga mtundu wa 1, umakhudza chidutswa cha myelin.
CMT imapezeka padziko lonse, ikukhudza anthu amitundu yonse. Anthu pafupifupi 150,000 ku United States ali ndi CMT ndipo 1 pa 2,500 padziko lonse amakhala ndi vutoli. Jean-Marie Charcot, Pierre Marie, ndi Howard Henry Tooth mu 1886, anayamba kufotokozera kuti CMT inayamba kufotokozedwa ndi Charcot-Marie-Tooth. Nthaŵi zina bungwe la CMT limatchedwa kuti peroneal muscular atrophy kapena choloŵa choloŵa m'thupi komanso zokhudzana ndi ubongo.
Matenda ambiri a Charcot-Marie-Tooth amaperekedwa pa majini, monga vuto la chromosomal. Pafupifupi 15 peresenti ya milandu imapezeka popanda mbiri ya banja. Matendawa amawoneka pakati pa zaka 15 ndi 20.
Kodi Zizindikiro Ndi Ziti?
Zizindikiro zoyamba za CMT nthawi zambiri zimatchulidwa ndi mavuto a mapazi, izi zingaphatikizepo zipsinjo zowonongeka, kukwapula, kapena kuwonekera mwachidwi.
Pamene matendawa akupita, phazi la phazi likhoza kukhala lokwezeka komanso zala zakuthwa. Zingakhale zovuta kwa anthu omwe ali ndi CMT kukweza mapazi awo. Anthu omwe ali ndi CMT ayenera kuyenda mosamala kwambiri, akugwada kuti akweze phazi lawo akuyenda.
Kufooka kwa manja kungayambe ndi vuto ndi kulemba kapena kugwiritsa ntchito zippers kapena mabatani.
Ululu ndi kupweteka kwa minofu kungapangitse.
Ngakhale pakati pa mamembala a banja limodzi, kuuma kwa CMT kungasinthe. Mwachitsanzo, munthu mmodzi sangathe kuona zizindikiro pomwe wina ali ndi zofooka ndi kuyenda kovuta. Anthu omwe ali ndi CMT angakhale achidule m'miyendo ndipo ali ndi maso oyang'anitsitsa.
CMT sichimakhudza mbali zina za thupi monga ubongo kapena mtima, luso la kulingalira, ndi chiyembekezo cha moyo zonse. Chikhalidwe sichitha, koma palibe mankhwala.
Pafupifupi 15 peresenti ya anthu omwe ali ndi CMT ali ndi mawonekedwe a matenda omwe ali okhudzana ndi X chromosome (yotchedwa CMTX). Kafukufuku wasonyeza kuti anthu omwe ali ndi CMTX akhoza kukhala ndi zizindikiro zamkati za mitsempha zochepa pambali pa zizindikiro zowonjezereka. Mavuto aakulu a CMT angayambitsenso mavuto a kupuma.
Kodi CMT Yadziwika Bwanji?
Ngati dokotala akukayikira CMT chifukwa cha kufooka kwa dzanja, mwendo, ndi phazi, mayesero apadera a mitsempha ( nerve conduction velocity , kapena NCV) ndi minofu ( electromyogram , kapena EMG) ikhoza kutsimikiziridwa kuti atsimikizidwe. Mayeso apadera a zamoyo akhoza kudziwa mitundu ina ya CMT.
Kodi CMT Yotani?
Popeza palibe mankhwala kapena njira yothandizira kuchepetsa matendawa, chithandizochi chimayang'ana kuthetsa zizindikiro.
Zovala zapamwamba ndi nsapato zapadera zingathandize kuyenda, monga mankhwala othandizira . Nthawi zina opaleshoni yapamtunda ( osteotomy kapena arthrodesis ) ingafunikire kukonza mapazi opunduka. Mankhwala angathe kuperekedwa kuti athetse kupweteka kwa minofu ndi kupondaponda.
Zotsatira:
Muscular Dystrophy Association. Mfundo Zokhudza Charcot-Marie-Tooth Disease (CMT).
Kedlaya, D. (2002). Matenda a Charcot-Marie-Tooth. eMedicine.
National Institute for Neurological Disorders ndi Stroke. Tsamba la Chidziwitso cha Charcot-Marie-Tooth Disorder.
Zwipp, H., Rammelt, S., Dahlen, C., & Reichmann, H. (1999). Mgwirizano wa Charcot. Orthopade, 28 (6), 550-558.