Kuyeza magazi kumathandiza kumaneneratu zotsatira zaumoyo
Kuyeza CD4 T-maselo n'kofunikira powathandiza madokotala kudziwa momwe angapewere ndi kachilombo ka HIV. Ngakhale kuti sakugwiritsidwa ntchito kuti adziwe ngati kachilombo ka HIV kakuyambitsidwa-mankhwala ayenera kuyambika panthaŵi yomwe amadziwidwa- angapereke madokotala lingaliro lomveka bwino la momwe munthuyo alili ndi zomwe zingachitike kuti apititse patsogolo nthawi yake thanzi.
Kumvetsetsa CD4 ndi CD8 T-maselo
Poyamba, ma lymphocytes ndi mtundu wa maselo oyera omwe amathandiza thupi kulimbana ndi matenda. Pali mitundu iwiri ikuluikulu ya ma lymphocytes: B-lymphocytes ndi T-lymphocytes. Mwa izi, pali mitundu iwiri ya ma selo T omwe timayang'anitsitsa panthawi ya HIV:
- CD4 T-maselo omwe ali ndi T-lymphocytes omwe ali ndi molecule yotchedwa CD4 pamwamba pawo. Amayambitsa chitetezo cha mthupi mwa kuyika maselo ena otetezeka a chitetezo cha m'magazi kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda monga mabakiteriya ndi mavairasi.
- CD8 T-maselo omwe ali ndi mamolekyu pamtundu wawo wotchedwa CD8. Izi ndi "T-lymphocyte" zakupha zomwe zimayambitsa kuwononga maselo omwe ali ndi kachilombo komanso kupanga tizilombo toyambitsa matenda omwe amamenyana ndi tizilombo toyambitsa matenda.
Mtengo wa CD4 Count Absolute
Mtheradi wa CD4 chiwerengero ndi kuchuluka kwa magulu ochuluka a CD4 T-maselo omwe akuyenda m'magazi anu. Pansi pake CD4 count, yochepa mphamvu ya chitetezo cha mthupi.
Mtheradi wa CD4 umayesedwa ndi kuyesa magazi mosavuta, zotsatira zake zomwe zimawerengedwa ngati chiwerengero cha CD4 maselo pamtunda wamagazimita imodzi. Anthu omwe alibe kachilombo ka HIV amakhala ndi ma CD4 omwe alipo pakati pa 600 ndi 1200 maselo a CD4 pamakilogalamu imodzi. Mosiyana ndi zimenezi, anthu omwe ali ndi kachilombo ka HIV omwe ali ndi kachilombo ka HIV amakhala ndi zaka zosachepera 500, malingana ndi siteji ya matenda, pamene anthu omwe ali ndi kachilombo ka HIV angathe kukhala ndi CD4 T-maselo pamtunda wa mamitamita imodzi.
Chiwerengero chonse cha CD4 chimaonedwa kuti ndicho chithunzithunzi chabwino kwambiri chomwe chingafanane ndi chiopsezo chotenga kachilombo ka HIV.
Chimene CD4 Percentage Ikutiuza
Magawo a CD4 amaimira kuchuluka kwa ma lymphocytes omwe ali ndi CD4 maselo ndipo amayesedwa pogwiritsa ntchito magazi omwewo monga momwe aliri ndi CD4 count.
Kawirikawiri, anthu omwe alibe kachilombo ka HIV adzakhala ndi CD4 peresenti ya pafupifupi 40 peresenti, pomwe CD4 ya anthu omwe ali ndi kachilombo ka HIV ingakhale yochepa kwambiri poyerekeza ndi 25 peresenti. Mwachidziwikiratu, kupitirira kwa chiwerengerocho, kulimbana kwakukulu kwa chitetezo cha mthupi.
Ngati CD4 yanu ili yochepa kuposa momwe mukuyembekezera, peresenti ya CD4 ikhoza kuiyika bwino mukulongosola izi ngati izi zikusintha kapena kusintha.
CD4 / CD8 Chidule monga Snapshot ya Health Immune
Njira imodzi yodziwira bwino momwe wodwala amatetezera ndi kuwonjezera peresenti ya CD4 / CD8 ya wodwalayo , yomwe imayeza kuchuluka kwa CD4 T-maselo poyerekeza ndi chiwerengero cha CD8 T-seli. Ndi mayesero, tiwone ngati matendawa akukulirakulira potsata kuwonongeka kwa maselo a T-kill mu zitsanzo za magazi.
Kawirikawiri, polimbana ndi matenda, pamene chitetezo cha mthupi chimatopa , sichikhoza kutulutsa maselo T kuti adziteteze. Kuchuluka kwa CD4 / CD8 kumatithandiza kuona izi.
M'zaka zaposachedwapa, kulimbikitsidwa kwakukulu pa CD4 / CD8 mu mphamvu ya anthu okalamba omwe ali ndi HIV . Kafukufuku wam'chipatala posachedwa waganiza kuti odwala pa ART, omwe amakhala ndi nthawi yaitali, omwe ali ndi kachilombo ka CD4 / CD8, amakhala ndi chiopsezo chowonjezereka cha matenda osokoneza bongo omwe alibe HIV.
Chifukwa Chake Mayeserowa Ndi Ofunika
Mtheradi wamtundu wa CD4 ndi magawo a CD4 amapatsa dokotala chidziwitso cha thanzi la chitetezo cha thupi lanu, komanso momwe matenda anu akuyendera.
Mwachidule, timadziwa kuti ma CD4 ochepa kuposa 200 amaika munthu amene ali ndi kachilombo ka HIV pangozi ya matenda opatsirana . CD4 peresenti, panthawiyi, imaganizira chiwerengero cha ma lymphocytes ndipo ndizofanananso zowonjezereka za thanzi labwino komanso la nthawi yaitali.
Ngati, ngati CD4 chiwerengero chiri chapamwamba chifukwa chakuti chiwerengero cha lymphocyte chiwerengero chiri chapamwamba, tidzakhalabe ndi chifukwa chodera nkhawa za thanzi la wodwalayo. Ngati, ngati CD4 ili yochepa chifukwa cha kuwerengeka kochepa kwa thupi, tingathe kumasulira zotsatira mosiyana.
> Chitsime:
> Gompels, M .; Dunn, D .; Phillips, A .; et al. "Kodi Kuphatikizana pakati pa CD4 Kuchuluka ndi CD4 Peresenti ya anthu omwe ali ndi kachilombo ka HIV kumakhudza zotsatira za mankhwala opatsirana kwambiri a Antiretroviral?" J Wopatsa Dis Dis. 2012; 205 (4): 540-547.
> Kuthamanga, R .; Huang, R .; Ledergerber, B ;; et al. "CD4 / CD8 chiŵerengero cha CD8 ndi ma CD8 akulosera kuyankha kwa CD4 mwa mankhwala omwe ali ndi kachilombo ka HIV ndi 1 komanso odwala pulogalamu." Mankhwala. 2016; 95 (42): e5094.