4 Zizolowezi Zowononga HIV

Momwe Mungasankhire Zomwe Mungapangire Moyo Wanu Zaka 15

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Kusagwirizana kwa mankhwala osokoneza bongo: Kutaya kwa zaka 10

Zakhala zatsimikizirika kuti matenda oyambirira ndi chithandizo cha kachirombo ka HIV angathe kuwonjezera chiyembekezo cha moyo . Ndipotu, kafufuzidwe kuchokera ku Multicenter AIDS Cohort Study (MAC) yatsimikizira kuti munthu amene amayamba mankhwala opatsirana pogonana (CD) pa CD4 amawerengera pamwamba pa maselo 350 / μL akhoza kukhala ndi moyo wautali wofanana kapena wamkulu kuposa wosagwidwa ndi HIV munthu aliyense. Ku US, zomwe zikutanthauzira ku moyo wa zaka pafupifupi 76 kwa amuna ndi zaka 81 kwa akazi.

Kulingalira lerolino ndikuti, pamene ART ikugwirizana ndi zopindulitsa kwambiri m'zaka za moyo, zizoloŵezi ndi zosankha za tsiku ndi tsiku zomwe timapanga zingathe kubwezeretsa zambiri-ngati sizinthu zonse-zapindulitsa. Chotsatira ndizo zizolowezi 4 zomwe zingachepetse moyo wanu zaka pafupifupi 15 komanso zomwe mungachite kuti muthe kusintha miyoyo yanu ngati muli ndi HIV.

Kuphonya mlingo wina uliwonse wa mankhwala anu omwe ali ndi kachilombo ka HIV ndi anthu okha. Kuchita chizoloŵezichi ndi chinthu china, osati kumangogwiritsira ntchito mankhwala osokoneza bongo, koma njira yomwe mukudwala.

Ngakhale mankhwala opatsirana pogwiritsa ntchito mankhwala opatsirana pogonana ali ovuta masiku ano kusiyana ndi kale, ndi mapiritsi ocheperapo, zotsatira zochepetsetsa zochepa, komanso zolembera zosavuta. Polephera kusunga nthendayi yosaoneka yomwe imapezeka , odwala amakhala osowa mankhwala pamene akutsutsana kwambiri ndi mankhwala awo. Zotsatira zake, zosankha zamtengo wapatali zimatayika, nthawi zambiri.

Kuchepetsa kusamalidwa kawirikawiri kumagwirizanitsidwa ndi kusamalidwa bwino kwa mankhwala , ngakhale pakati pa iwo omwe ali ndi kachilombo kochepa kwambiri. Kafukufuku wochokera ku yunivesite ya McGill ku Montreal wanena kuti odwala omwe ali ndi "mavitamini omwe ali pafupi" omwe amapezeka (mwachitsanzo, pakati pa 50 ndi 199 makope / mL) ali ndi chiopsezo chachikulu cha mankhwala osapatsirana ndi 400 peresenti kusiyana ndi omwe ali ndi kachilombo ka HIV.

Mu 2015, Ku United Collaborative HIV Cohort (UK CHIC) Phunziro linayang'ana momwe zimakhudzidwira ndi ma ARV pa moyo wa munthu ndipo zinatsimikizira kuti munthu wazaka 35 sangakwanitse kukwaniritsa chiwerengero cha tizilombo toyambitsa matenda pamene ART imatha kuyerekezera 10 zaka za nthawi yokhala ndi moyo, ngakhale CD4 chiwerengero chinali pamwamba pa maselo 350 / μL.

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Kugwiritsa Ntchito mankhwala osokoneza bongo: Kutaya kwa zaka 11

Kugwiritsira ntchito mankhwala osokoneza bongo sikungogwirizanitsa ndi chiopsezo chachikulu chotenga kachilombo ka HIV ndi matenda a chiwindi , komanso kungathe kupha imfa chifukwa cha matenda opatsirana ndi Edzi, ngakhale pakati pa iwo omwe angathe kuthandizira kupatsirana kachilombo ka HIV.

Kafukufuku wochokera ku British Columbia Center for Excellence ku HIV / Edzi ku Vancouver adafufuza mitengo ya moyo wa anthu 2,637 omwe amagwiritsa ntchito mankhwala osokoneza bongo omwe ali ndi kachilombo ka HIV, pa zaka 20, akusonkhanitsa nthawi ndi zifukwa za imfa ya anthu 200 omwe adamwalira pazaka zisanu ndi ziwiri. Ngakhale kuti anthu oposa 19 pa 100 alionse anafa chifukwa cha kupitirira malire ndi kudzipha, kachilombo ka HIV ndi matenda okhudzana ndi matendawa amachititsa kuti ambiri azikhala ndi moyo, mogwirizana ndi imfa ya zaka zoposa 11 zapadera mosasamala kanthu za chikhalidwe cha mankhwala.

Phunziro lofanana ndilo kuchokera ku Tufts-New England Medical Center linayang'aniranso ma 656 IDU pa zaka zisanu ndipo linatsimikizira kuti ambiri mwa anthu omwe ali ndi kachilombo ka HIV (66 peresenti) adatengedwa kuti ali ndi HIV kapena matenda ena, Wachitatu anali wogwirizana ndi kugwiritsa ntchito mankhwala osokoneza bongo kapena chiwawa.

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Kusuta: Kutaya kwa zaka 12

Kusuta , monga chinthu chodziimira, kumaonedwa kukhala ndi zotsatira zowopsa kwambiri pa matenda ndi imfa mwa anthu omwe ali ndi kachilombo ka HIV kuposa matenda ena onse omwe ali ndi HIV kapena omwe alibe HIV. Chomwe chimapangitsa ichi kukhala chovuta kwambiri ndi chakuti anthu omwe ali ndi kachirombo ka HIV amatha kusuta fodya kusiyana ndi anthu omwe alibe kachilomboka ndipo amayamba kukhala ndi matenda omwe amasuta fodya zaka 10 mpaka 15 poyambirira.

Phunziro la 2013 kuchokera ku Copenhagen University Hospital linanena kuti kusuta, komweko, kumachepetsa moyo wokhala ndi zaka 12 kwa anthu omwe ali ndi kachilombo ka HIV-kuphatikizapo chiopsezo cha matenda a mtima, kuphatikizapo chiopsezo cha imfa kuchokera ku matenda osokoneza bongo (COPD) ), komanso kuonjezera chiopsezo cha khansa ya m'mapapo ndi masentimita 1400 poyerekeza ndi anthu ambiri.

Mosiyana ndi zimenezi, kusuta fodya pakati pa anthu omwe ali ndi kachilombo ka HIV kumagwiridwa ndi kuchepetsa matenda a mtima wa 65 peresenti patatha zaka zitatu zokha komanso 50 peresenti akugwetsa chiwopsezo cha khansa yamapapo patapita chaka chimodzi.

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Kuchepetsa HIV Kuchiza: Kutaya kwa zaka 15

Kukonzekera ndi kupewa ndi zizolowezi ziwiri zomwe munthu yemwe ali ndi kachilombo ka HIV sangathe kuchita, makamaka pankhani ya kachilombo ka HIV. Mwa kuchedwa kwa chithandizo kwazaka zambiri, ngakhale zaka makumi ambiri, mumalola kuti kachilombo ka HIV kasateteze chitetezo chanu cha thupi pamene mukugonjetsa thupi lanu zaka zambirimbiri zomwe zimatha kuyambitsa matenda okalamba .

Akatswiri ochokera ku UK CHIC Studies anapeza kuti munthu amene amachedwa kumwa mpaka kachilombo ka CD4 kawiri kamene kakagwa pansi pa maselo 350 / μL akhoza kuyembekezera kukhala ndi moyo zaka 15 kupatula munthu amene ayambira pamwamba pa maselo 350 / μL. Pachilombochi, kuyamba mankhwala pa nthawi ya chidziwitso , mosasamala za CD4 count, sikungowonjezera mwayi wokhala ndi moyo wokhala ndi moyo wamba koma kumachepetsa chiopsezo cha matenda a HIV ndi omwe alibe kachilombo ka HIV mwa magawo 53 peresenti.

> Zotsatira:

> KUYAMBA KUYAMBIRA Gulu Lophunzira. "Kuyambitsidwa kwa mankhwala opatsirana pogonana ku Antiymmetomatic HIV Infection." New England Journal of Medicine. July 20, 2015; DOI: 10.1056 / NEJMoa1506816.

> Laprise, C ;; de Pokomandy, A .; Baril, J ;; et al. "Kulephera kwa virologic potsatira chidziwitso chochepa cha viremia mu gulu la odwala kachilombo ka HIV: zotsatira za zaka 12 zoziwona." Matenda opatsirana pogonana. November 2013; 57 (10): 1489-96

> May, M .; Gompels, M .; Delpech, V .; et al. "Ndili ndi chiyembekezo cha moyo wa anthu omwe ali ndi kachilombo ka HIV-1 omwe ali ndi kachilombo ka CD4 + komanso momwe amachitira ma ARV chifukwa cha mankhwala opatsirana pogonana." AIDS. May 15, 2014; 28 (8): 1193-1202.

> Helleberg M .; Afzal, S .; Kronborg, G ;; et al. "Kufa kumayambira chifukwa chosuta fodya pakati pa anthu omwe ali ndi kachilombo ka HIV. Matenda opatsirana pogonana. March 2013; 56 (5): 723-734.

> Clifford G ;; Lise, M .; Franceschi, S .; et al. "Khansa ya m'magazi m'maphunziro a gulu la HIV / Swiss: gawo la kusuta fodya, matenda a immunodeficiency ndi matenda a pulmonary." British Journal ya Cancer. January 12, 2012; 106 (3): 447-452.