Lymphoma ya Mayesero
Kodi testicular lymphoma ndi yotani kusiyana ndi mitundu ina ya lymphoma yomwe si ya Hodgkin?
Mwachidule
Lymphoma ingakhudze ma testes m'njira zingapo. Kachilombo kamene kamayambitsa mayesero, omwe amatchulidwa kuti primary testicular lymphoma, kapena kuti lymphoma angaphatikizepo mayesero ngati mbali ya matenda ambiri omwe amaphatikizapo malo ena ambiri.
Kukula
Ma testes si malo wamba a lymphoma.
Ndipotu, mayesowa amapezeka kwambiri ndi khansa ina yotchedwa kachilombo khungu. Anthu osachepera 5% omwe ali ndi khansa m'mayesero ali ndi lymphoma. Kwa anthu opitirira zaka 50, komabe lymphoma ndi khansa yowopsa kwambiri ya ma testes monga maselo a majeremusi m'zaka zapakati pano ndi osowa.
Mitundu
Lymphoma ya ma testes nthawi zambiri imakhala mtundu wosakhala wa Hodgkin's lymphoma (NHL) . Mtundu wowonjezereka uli wofala kwambiri B-cell lymphoma . Mitundu ina ndi immunoblastic lymphoma, Burkitt lymphoma (mwa ana), ndi follicular lymphoma .
Pali mawu angapo omwe mungamve ngati mukupezeka ndi testicular lymphoma. Imodzi ndi " kuwonetsera kwamphamvu ." Primary predranodal lymphoma kumangotanthauza kuti lymphoma imapezeka koyamba (yotuluka) kunja kwa thupi la mimba, mwazinthu zina, imapezeka mu mayesero poyamba osati mu mitsempha yam'mimba, mphala, fupa, kapena thymus.
Ma testes (pamodzi ndi dongosolo loyamba la mitsempha) amatchedwanso malo opatulika .
Zimayambitsa
Sindikudziŵa chomwe zimayambitsa testicular lymphoma, koma pali zifukwa zingapo zomwe zimayambitsa matenda omwe si a Hodgkin lymphoma . Pali chiyanjano ndi matenda a tizilombo, makamaka EBV (Epstein-Barr virus yomwe imayambitsa mono) , CMV (matenda a cytomegalovirus) , parvovirus B19 (kachilombo kamene kamayambitsa matenda a "fifth" HIV.
Zizindikiro ndi Zizindikiro
Chizindikiro chofala ndikutambasula kwa mayesero awiriwa. Nthawi zambiri zimakhala zopweteka pang'ono kapena zopweteka zogwirizana ndi izi. The testis angakhale wolemetsa. Ngati lymphoma yafalikira kumbali zina za thupi, pakhoza kukhala zizindikiro zokhudzana ndi mbali zomwe zakhudzidwa. Pakhoza kukhala chimodzi kapena zingapo za B-zizindikiro za lymphoma - malungo, kutaya thupi kapena thukuta usiku.
Kudziwa
Chinthu chowonjezera chikhoza kukhala ndi zifukwa zambiri, ndipo dokotala wanu amatha kuzindikira mosavuta zinthu zomwe zimagwirizana komanso zosavuta. Ngati pali chikayikiro cha chotupa, pulogalamu ya ultrasound kapena CT ya testes idzavomerezedwa ngati mayeso oyambirira. Mayeso ena a magazi chifukwa cha zotupa zimatengedwa kuti apeze tizilombo toyambitsa matenda, tizilombo toyambitsa matenda. Njira yabwino yodziwira mtundu weniweni wa chotupa ndicho kuchotsa testis ndi opaleshoni yosavuta. Kuyezetsa singano kapena kachilombo kawirikawiri sikoyenera chifukwa cha chiopsezo cha "mbeu" - kufalikira maselo a khansa kuzungulira dera lomwe singano imayikidwa. Mitundu yonyamulira yamtunduwu imayang'aniridwa ndi microscope, ndipo matenda opatsirana amatha.
Mayesero Atatha Kudziwa
Ngati chotupa cha testicular ndi lymphoma, mayesero amafunika kuti chithandizo chisayambe. Izi nthawi zambiri zimaphatikizapo CT mapulogalamu a mimba ndi chifuwa komanso mayeso a mafupa .
Testicular lymphoma ikhozanso kufalikira mu cerebrospinal fluid (CSF) yomwe ikuyenda mkati mwa ubongo ndi msana. Kupuma kwapopu (pampopu wamtsempha) kungathetsedwe kuti kuchotserako kachilombo kameneka kuchokera kumsana kumbuyo kwake ndikuyesera maselo a lymphoma.
Kuchiza
Chithandizo cha khansa ya testicular chimaphatikizapo kuchotsa chotupacho, koma chithandizo chofunika chofunika kuti tipewe khansara kubwereranso mu ziwalo zina, pakatikati pa mitsempha, ndi malo ena otchedwa extranodal.
Opaleshoni - Kuchotsa tizilombo (orchiectomy) ndi gawo loyamba la mankhwala ndipo nthawi zambiri limakhala ngati gawo la matenda.
Chemotherapy - The chemotherapy regimen CHOP nthawi zambiri amaperekedwa pamodzi ndi Rituxan. Mankhwalawa mu regimen awa ndi Cytoxan (cyclophosphamide), Adriamycin (doxorubicin), Oncovin (vincristine), ndi prednisone.
Njira yothandizidwa - Rituxan (rituximab) ndi anti-monoclonal antibody omwe nthawi zambiri amaperekedwa pamodzi ndi chemotherapy. Thupi lathu limapanga ma antibodies kuti amenyane ndi mabakiteriya ndi mavairasi. Rituxan kwenikweni ndi mankhwala opangidwa ndi anthu opangidwa kuti amenyane ndi maselo a lymphoma.
Mafunde - Mvula imatchulidwa kawirikawiri kumadera amtunduwu, makamaka kuchepetsa mwayi wa khansa yomwe imabwereranso muzinthu zina.
Central nervous system prophylaxis - Chigawo chachikulu cha nervous system prophylaxis nthawi zambiri chimaphatikizidwa ngati gawo la chithandizo choletsa kuti mliriwu ulalikire kapena kubwereranso m'katikati mwa manjenje.
Kusunga Chonde
Kawirikawiri testicular imayenera kuchotsedwa, koma chemotherapy ndi mankhwala omwe amachititsa kuti tizilombo tizilombo tizilombo tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda. Mwamwayi banki yamabungwe ndi njira yabwino kwa amuna ambiri. Onetsetsani kuti mukulankhulana ndi dokotala wanu za kusungira chonde pa chithandizo cha khansa kotero mumadziwa zonse zomwe mungasankhe musanayambe mankhwala.
Kulimbana ndi Kuthandizidwa
Ngati mwapezeka kuti muli ndi testicular lymphoma mumakhala mukudandaula. Popeza ichi ndi chotupa chosadziwika kwambiri chomwe mumakhala nacho chokha, ndipo dzifunseni kuti mungathe kuyankhula ndi ndani. Pitani kwa achibale ndi abwenzi. Ganizirani kulumikizana ndi khansa pamudzi. Tikukhala mu nthawi yomwe mungapeze ena ndi testicular lymphoma kuzungulira dziko lapansi, ndipo angathe kupeza chithandizo ndi anthu kuti awononge maganizo pa 24/7. Fufuzani ndi kuphunzira za matenda anu , ndipo chitani mbali yogwira ntchito yanu. Mankhwalawa ndi owopsa, koma mosiyana ndi khansa zambiri zimapereka mpata wabwino wodwala matendawa kwa nthawi yaitali.
Zotsatira:
Khansa: Mfundo ndi Zolemba za Oncology 7th Edition. Okonza: DeVita VT, Hellman S, Rosenberg SA. Lipincott Williams & Wilkins 2005.
Chapuy, B., Roemer, M., Steward, C. et al. Zomwe zimayambitsa matenda a masewera oyambirira a testicular ndi oyambirira a mitsempha yam'mimba. Magazi . 2016. 127 (7): 869-81.
Cheah, C., Wirth, A., ndi J. Saymour. Primary testicular lymphoma. Magazi . 2014. 123 (4): 486-93.
Huang, Y., Zhang, Z., Tashkin, D., Feng, B., Straif, K., ndi M. Hashibe. Kufufuza za matenda osuta chamba ndi khansa. Khansa Epidemiology Zida ndi Kupewa . 2015. 24 (1): 15-31.
Vitolo, U., Chiappella, A., Ferreri, A. et al. Chithandizo choyamba cha primary testicular chimafalitsa kwambiri B-cell lymphoma ndi rituximab-CHOPD, CNS prophylaxis, ndi njira yotsutsana nayo: zotsatira zomaliza za mayesero apadziko lonse. Journal of Clinical Oncology . 2011. 29 (20): 2766-72.
Yousif, L., Hammer, G., Blettner, M., ndi H. Zeeb. Khansara ya Testicular ndi matenda opatsirana ndi mavairasi. Journal of Virology Medical . 2013. 85 (12): 2165-75.