Kodi zizindikiro za B ndi ziti?

Funso: Kodi zizindikiro za B ndi ziti?

Yankho:

B-zizindikiro zingathenso kutchulidwa kuti "systemic systems" kapena "zizindikiro zowonekera," koma pankhani ya lymphoma, mawuwo amatanthauza zizindikiro zitatu zomwe zingagwiritse ntchito momwe matendawa angakhalire:

• Kutentha (kutentha, kutentha> 38 ° C [> 100.4 ° F]) kwa masiku atatu otsatizana
• Kutaya thupi mopanda kuyesera, kupitirira 10% ya kulemera kwa thupi mu miyezi isanu ndi umodzi

• Kutseka usiku kukuwombera

Munthu amene ali ndi lymphoma ndi chimodzi mwa zizindikiro zitatu pamwambapa akunenedwa kuti ali ndi zizindikiro B. Pali mitundu iwiri ikuluikulu ya lymphoma: Hodgkin lymphoma (HL) ndi osakhala Hodgkin Lymphoma (NHL). Odwala amtundu wa lymphoma akhoza kukhala ndi zizindikiro B. Chimodzi mwa zizindikiro zowopsa kwambiri za lymphoma, makamaka, ndikutambasula kwa ma lymph nodes. Zizindikiro B zingakhalepo pakakhala zosiyana siyana za lymphoma koma pomwe zilipo, zingathandize kuthana ndi momwe lymphoma idzachitira komanso mankhwala omwe angakhale abwino kuyamba nawo. Zizindikiro za B zimapezeka m'maymphini okula mofulumira kwambiri.

Zambiri pa Zizindikiro B ndi Zofunikira Zake

Nthawi zina, zizindikiro za B zikhoza kusonyeza kuti matendawa angakhalepo mbali zina za thupi kusiyana ndi kumene adapezeka poyamba. Kukhalapo kapena kusapezeka kwa zizindikiro za B panthaŵi ya kugonana kungaphatikizidwe mu kufotokoza kwa matenda a munthu.

Dokotala akamapanga siteji ya matendawa ndipo munthuyo ali ndi zizindikiro B, amawonjezera kalata B pambuyo pa siteji (yomwe ingakhale pakati pa ine ndi IV). Kotero ngati wina ali siteji yachiwiri ndi B-zizindikiro, sitejiyi imadziwika kuti II-B. Zigawo za omwe alibe zizindikiro za B zimatchedwa A.

Pali mitundu yosiyanasiyana ya lymphoma, ndipo mitundu yosiyanasiyana ya lymphoma ingakhudze odwala mosiyana. Mofananamo, kukhalapo kwa zizindikiro B kungakhale kofunikira kwambiri nthawi zina za lymphoma, koma mochepa mu mitundu ina ya lymphoma.

B-Zizindikiro Zogwirizana ndi Kusintha

Mitundu iŵiri ya mitundu yonse ya NHL ndi follicular lymphoma (FL) ndipo imakhala yaikulu kwambiri B-cell lymphoma (DLBL). Follicular lymphoma imaonedwa kuti ndi yopweteka kwambiri kapena yochedwa kukula, yomwe imatanthauza kuti "ikhoza" kwa zaka zambiri isanafike ku matenda oopsa komanso ofulumira kwambiri. Pamene FL imasintha kuchoka ku fungo, imatchedwa kusintha.

FL ingasandulike kukhala DLBCL, lymphoma yowopsya komanso yofulumira kwambiri. Nthawi zina, munthu yemwe ali ndi FL sanadziwe kuti ali ndi lymphoma ndipo amangopita kuchipatala kamodzi pamene matendawa asintha. Chimodzi mwa zinthu zomwe zingapangitse munthu kupeza chithandizo chamankhwala ndi kukhalapo kwa B-zizindikiro.

Posachedwapa kagulu ka ofufuza adawona zinthu zogwirizana ndi kusintha kwa FL pakati pa odwala 2,652. Pambuyo powayang'ana kwa zaka 6-7, pafupifupi 14 peresenti ya iwo adasinthidwa atangoyamba kumene kugonana, kuphatikizapo 147 biopsy-confirmed ndi 232 odwala milandu.

Iwo anaganiza kuti kuloŵerera kwa lymphoma kunja kwa maselo a mitsempha, kukwera kwa magazi chizindikiro chotchedwa lactate dehydrogenase, ndi zizindikiro za B zomwe zimagwirizanitsidwa ndi kusintha kwa chiopsezo.

_Zotsatira

_{Wagner-Johnston ND, Link BK, Byrtek M, et al. Zotsatira za transformed follicular lymphoma m'nthawi yamakono: lipoti la National LymphoCare Study (NLCS). Magazi . 2015; 126 (7): 851-857}

_{Kupenda Mankhwala ndi Opaleshoni mu Hematologic Malignancies yokonzedwa ndi Martin S. Tallman, Leo I. Gordon}

_{Matenda a Malignancies. Demos Kusindikiza Zamankhwala, Dec 17, 2012}