Zimene Kafukufuku Amasonyeza
Chimanga chogwiritsira ntchito zachipatala ndizovuta kwambiri, kuphatikizapo, mwalamulo, ndi ndale. Komabe, umboni wa sayansi ukupitirizabe kunena kuti ukhoza kukhala mankhwala otetezeka komanso othandiza kwa mazunzo ambiri, kuphatikizapo fibromyalgia .
Tili ndi mavitrahydrocannabinol (THC) omwe amagwiritsidwa ntchito pamsika, zomwe zimagwirizanitsa ndi "mkulu" wa chamba.
Komabe, kafukufuku akusonyeza kuti mankhwala ena a mmunda angakhale ndi mankhwala othandizira.
Musanakambirane za zotsatira zogwiritsira ntchito chamba cha mankhwala pa fibromyalgia, zimathandiza kudziwa pang'ono za chinachake chomwe chimatchedwa cannabinoid, kapena endocannabinoid.
Kodi Matenda a Endocannabinoid Ndi Chiyani?
"Wopanda" amatanthauza chinachake chomwe chimachokera mkati mwa thupi lanu-chinachake chimene mwachibadwa chimakhalapo.
"Cannabinoid" imachokera ku mawu akuti cannabis, omwe ndi dzina lenizeni la chomera cha marijuana, ndipo limatanthawuza ziwalo za thupi lanu zomwe zimachitidwa ndi khansa. Tonsefe tiri ndi zida zowonongeka m'thupi lathu, ndipo zambiri zingatheke chifukwa cha kusuta kapena kusuta mbodya kapena kusintha kwake.
Njira yamakono yowonjezereka ikuphatikizidwa mu njira zambiri, zomwe zambiri zimadziwika kapena zimawerengedwa kuti zimakhala zovuta mu fibromyalgia. Izi zikuphatikizapo:
- Mphamvu yamagetsi
- Chitetezo cha mthupi
- Kumbukirani
- Kupweteka kwachisoni
- Kugona
- Kusokonezeka maganizo
- Malamulo otentha
- Njira yowonongeka yaumadzi
Papepala la 2004 la dongosolo la endocannabinoid linanena kuti fibromyalgia, matenda opweteka a m'mimba, ndi zikhalidwe zowonjezereka zikhale "monga matenda odwala endocannabinoid a syndromes." Amatchulanso zofufuza zomwe zimayambitsa matendawa ndi chizindikiro cha schizophrenia, multiple sclerosis, matenda a Huntington, matenda ena a Parkinson, matenda ena a anorexia, ndi matenda aakulu.
Kafukufuku omwe akukula kuti chithunzithunzi cha fibromyalgia chikhoza kukhala chosowa m'maganizo otchedwa endocannabinoids chimadzutsa funso lodziwika bwino: kodi kuchulukitsa kuchulukitsa kwa mankhwalawa kumathandiza kusintha ntchito ndikuchepetsa zizindikiro? Ngati ndi choncho, ndi zizindikiro ziti zomwe sing'anga zamankhwala (kapena kupanga zofanana) zimachepetsa?
Kafukufuku wa Marijuana Zamankhwala & Fibromyalgia
Kuyambira chaka cha 2014, kafukufuku wa kafukufuku wamankhwala pa chamba cogwiritsira ntchito fibromyalgia, komanso zochitika zokhudzana ndi matenda a m'mimba ndi migraine, anati:
- Kuperewera kwa endocannabinoid kumathandiza pazinthu izi
- Nyamayi imatha kuletsa njira za m'mimba, m'mimba komanso m'mimba
- Chidziwitso chachipatala chikugwirizana ndi zotsatirazi
Kafukufuku amasonyeza kuti chamba chimatha kwambiri:
- Kuchepetsa ululu (kuphatikizapo kupweteka kwa nociceptive, yomwe ndi gawo la fibromyalgia)
- Pewani kuuma
- Kutupa Kwambiri (kuphatikizapo kutupa kwa myofascial, zomwe zingakhale ndi gawo mu fibromyalgia)
- Limbikitsani kumasuka
- Kuwonjezera kugona
- Kuonjezera maganizo a moyo wabwino
Kafukufuku wina adawonanso kuti ogwiritsira ntchito mankhwala osokoneza bongo ali ndi chiwongolero cha thanzi labwino kuposa osagwiritsa ntchito. Chimodzi, chomwe chinkawona zotsatira za mankhwala omwe amachitidwa ndi nabilone, amasonyeza kuti mlingo wotsika usiku ungathandize kugona mu fibromyalgia ndipo ukhoza kuwonedwa kuti ndi njira ina yowonjezera yodzitetezera amitriptyline.
Kufufuza kwa 2012 kunayang'ana kuchuluka kwa chamba chimagwiritsa ntchito fibromyalgia. Ofufuza apeza kuti pafupifupi 13 peresenti ya ophunzira anali kugwiritsa ntchito mankhwalawa kuti athetsere zizindikiro zawo. Mwa awa, oposa 80 peresenti anali kugwiritsa ntchito mosaloledwa.
Akatswiri ofufuza anapeza kuti kugwiritsira ntchito marijuana kunali kovuta kwambiri kwa odwala fibromyalgia omwe ali ndi matenda osagwedera. Chiyanjano cha mbidzi chimagwiritsidwa ntchito ndi matenda a m'magulu m'gulu lino sichidziwika.
Kugwiritsira ntchito mankhwala osokoneza bongo kunalinso kofala pakati pa amuna, osagwira ntchito, komanso omwe analandira malipiro olemala.
Zotsatira Zotsatira
Ndemanga ya 2011 inanena kuti zida zowonongeka zimakhala zotetezeka ndipo zimagwiridwa ndi zotsatira zoyipa kapena zochepa zomwe zinkakhala zolekerera, komanso kuti chiwongolero chotsitsa chifukwa cha zotsatira zake chinali chochepa.
Zotsatira zowonongeka zikuphatikizapo:
- Chizungulire
- Nausea
- Mlomo wouma
- Ataxia (kuchepetsa kuchepetsa kayendedwe ka thupi)
Komabe, phunziro la 2014 likusonyeza kuti tikusowa kafukufuku wa nthawi yayitali kuti tidziwe zomwe zingakhale zovuta kwa nthawi yayitali, komanso kuti zingakhale zoopsa za kugwiritsira ntchito molakwa ndi kusokoneza bongo.
Zochiritsira Zogwiritsira Ntchito Marijuana
Mankhwala ena amatsenga ali pamsika ku US Mankhwala awa ndi awa:
- Marinol (dronabinol)
- Cesamet (nabilone)
Chimanga chachipatala n'chovomerezeka m'mayiko ambiri. Mankhwalawa akhoza kusuta, kudyedwa (monga chakudya chophika), kapena kupukutidwa. Mafuta kapena mavitamini angakhale otetezeka komanso osavuta kuti anthu ena alolere.
Chifukwa chakuti amatha kukhala osokoneza bongo, anthu ena amavomereza kuti azidzisamalira mosasamala. Izi zimadza ndi zoopsa zake, kuphatikizapo:
- Kumangidwa, kuimbidwa mlandu ndi kumangidwa ndi mlandu
- Kulandira chamba ndi zinthu zomwe zingakhale zoopsa
- Kulandira mankhwala osakwanira
Anthu ogwiritsira ntchito chamba mosalongosoka angakhalenso osakayika kuti awawuze ogwira ntchito zawo zaumoyo za izo. Izi zingayambitse mavuto pogwiritsa ntchito mankhwala kapena, pokhapokha ngati akulephera kuchitapo kanthu, amachititsa madokotala kuti asamvetsetse vutoli. Kuti mukhale otetezeka, nthawi zonse muzidziwitsa dokotala ndi wamankhwala za mankhwala onse omwe mukuwatenga.
Matenda ena a Endocannabinoid System
Kafukufuku amasonyeza kuti mankhwala ena ambiri, malemba ndi ena, amakhudza dongosolo la endocannabinoid. Izi zikuphatikizapo:
- Painkillers ( acetaminophen , NSAIDs , opioids , glucocorticoids)
- Mankhwala oletsa kuteteza thupi ( amitriptyline , duloxetine )
- Antipsychotics
- Kudandaula ndi mankhwala
- Mankhwala osokoneza bongo ( pregabalin , gabapentin)
Mankhwala osagwiritsa ntchito mankhwala omwe angakhale othandiza ndi awa:
- Kuchiza
- Myofascial manipulation
- Kupangidwanso
- Zakudya
- Mankhwala amitsamba
Zochita za moyo kuphatikizapo zakudya ndi zochita masewera olimbitsa thupi zingayambitsenso kusintha kwa dongosolo la endocannabinoid. Mofanana ndi njira iliyonse yothandizira kapena chithandizo, muyenera kulankhula ndi dokotala za zomwe mungachite bwino.
Zotsatira:
Benyamina A, Reynaud M. La revue wa practitioner. 2014 Feb; 64 (2): 165-8. (Nkhani mu Chifalansa. Zomwe zimatchulidwa.) Kugwiritsa ntchito mankhwala opangidwa ndi khansa.
Fiz J, et al. PLoS One. 2011 Apr 21; 6 (4): e18440. Mankhwalawa amatha kugwiritsa ntchito odwala omwe ali ndi fibromyalgia: zotsatira za kupuma kwa zizindikiro ndi umoyo wokhudzana ndi thanzi.
Lynch ME, Campbell F. British Journal ya zamankhwala zamankhwala. 2011 Nov; 72 (5): 735-44. Mankhwala osokoneza bongo omwe amachiza matenda osamva khansa osatha; kuwonongeka mwatsatanetsatane kwa mayesero osadziwika.
McPartland JM. Journal of bodywork ndi kayendetsedwe ka mankhwala. 2008 Apr; 12 (2): 169-82. Kufotokozera za endocannabinoid dongosolo mu fibroblasts ndi myofascial tissues.
McPartland JM, Guy GW, Di Marzo V. PLoS One. 2014 Mar 12; 9 (3): e89566. Kusamalira ndi kudyetsa njira yotchedwa endocannabinoid: kuwonetsetsa mwachidwi njira zothandizira zachipatala zomwe zimayendera dongosolo la endocannabinoid.
Russo EB. Neuro endocrinology makalata. 2004 Feb-Apr; 25 (1-2): 31-9. Kulephera kwachipatala kumapeto kwa (CECD): Kodi lingaliroli lingathe kufotokozera zachipatala phindu la nthendayi mu migraine, fibromyalgia, matenda osakondweretsa amagazi ndi zina zomwe zimakhala zosagwira ntchito?
Smith SC, Wagner MS. Malembo a Neoor endocrinology. 2014; 35 (3): 198-201. Kulephera kwachipatala kotchedwa endocannabinoid (CEC D) kubwereranso: kodi lingaliroli lingalongosole chithandizo cha mankhwala opatsirana pogonana mu migraine, fibromyalgia, matenda opweteka a m'mimba ndi zinthu zina zosagonjetsa mankhwala?
Ste-Marie PA, ndi al. Kusamalira nyamakazi ndi kafukufuku. 2012 Aug; 64 (8): 1202-8. Mgwirizano wa mankhwala a zitsamba amagwiritsa ntchito magawo osokoneza maganizo pa odwala omwe ali ndi fibromyalgia.
Ware MA, et al. Anesthesia ndi analgesia. 2010 Feb 1; 110 (2): 604-10. Zotsatira za nabilone pamene wagona mu fibromyalgia: zotsatira za mayesero olamuliridwa mwadzidzidzi.